Yazar "Oguz, Fatih" seçeneğine göre listele

Listeleniyor 1 - 3 / 3
  • [ X ]
    Öğe
    Effects of acute exercise on the diameter of the spermatic vein, and duration of reflux in patients with varicocele
    (Informa Healthcare, 2013) Atar, Murat; Soylemez, Haluk; Oguz, Fatih; Beytur, Alt; Altunoluk, Bulent; Kahraman, Bayram; Islamoglu, Yahya
    Objective. The aim of this study was to investigate the effects of acute exercise on the diameter of the spermatic vein, and on the duration of reflux in patients with varicocele. Material and methods. The study included 38 patients with complaints of infertility and scrotal pain between 2009 and 2010. The diagnoses were made by physical examination and colour Doppler ultrasound, with both performed before and after exercise tests. Results. The mean age of the participants was 25.7 +/- 4.9 years. During the first examination, the grades of the varicoceles detected were as follows: grade I, n = 7; II, n = 10; and III, n = 21. The diameters of veins in patients with grades I, II and III varicocele were 2.1 mm, 2.9 mm and 4.2 mm, respectively, before exercise, whereas they were 2.6 mm, 3.2 mm and 4.3 nun, respectively, after exercise. In patients with grade I varicoceles, compared with pre-exercise values, the diameter of the left spermatic vein and duration of reflux measured during Valsalva manoeuvres were increased significantly after exercise (p = 0.042 and p = 0.034, respectively); similar results were obtained for the patients with grade II varicoceles (p = 0.007 and p = 0.008, respectively). However, the minimal relative increase in cases with grade III varicoceles was not statistically significant (p > 0.05). Conclusions. This study demonstrates that acute exercise increases the spermatic vein diameter and reflux time in patients with varicoceles. These outcomes demonstrate that acute exercise may be an aggravating factor for varicocele, as seen in chronic exercise.
  • [ X ]
    Öğe
    Evaluation of antioxidant effect of resveratrol on testicular tissue in rats that were exposed to cigarette smoke
    (Aves, 2011) Soylemez, Haluk; Ugras, Yahya Murat; Beytur, Ali; Oguz, Fatih; Kurus, Meltem; Karabulut, Aysun Bay
    Objective: The aim of this study was to investigate the negative effects of cigarette on testicular biochemistry and histology of rats and to evaluate if resveratrol could alter these effects. Materials and methods: Thirty-two male Wistar Albino rats were divided into 4 grups for an experiment of 6 weeks. Group 1 was used as control; Group 2 was only exposed to cigarette smoke. Group 3 only received intraperitoneal injections of resveratrol (10 mg/kg/day). Group 4 was exposed to both cigarette smoke and resveratrol (10 mg/kg/day). At the end of the experimental period, the rats were sacrified and testes of all rats were removed. Malondialdehyde (MDA), glutathione (GSH), and nitric oxide (NO) levels were measured on testicular tissue and histopathologic examination was performed with light microscope. Results: Weight follow-up of rats revealed no significant difference among groups. MDA level was lower in cigarette smoke and resveratrol group than that of only cigarette smoke group. GSH level showed significant decrease in only cigarette smoke group, while GSH level increased in cigarette smoke and resveratrol group. Differences in NO levels were not statisticaly significant among groups. The histological evaluation revealed that Johnsen score which indicates spermatogenesis was significantly lower only in cigarette smoke rats than all other groups. Conclusion: Oxidative stress develops in testis of rats that were exposed to cigarette smoke, and resveratrol has preventive effects on this damage with direct or indirect antioxidant activity.
  • [ X ]
    Öğe
    Evaluation of children with inguinoscrotal ectopic adrenal tissues
    (Tubitak Scientific & Technological Research Council Turkey, 2013) Oguz, Fatih; Yildiz, Turan; Beytur, Ali; Soylemez, Haluk; Altintas, Ramazan; Samdanci, Emine; Alan, Saadet
    Aim: To evaluate 6 cases of inguinoscrotal ectopic adrenal nodules, which were detected in 2 hospitals. Materials and methods: A total of 296 male patients who had inguinoscrotal surgery between 2009 and 2011 were retrospectively evaluated. Bright yellow nodular lesions, resembling the adrenal tissue, were excised during surgery. Histopathologic examination of these samples was performed and the clinical data of the patients were evaluated. Results: Ectopic adrenal tissue was detected in 6 patients (2.02%). The mean age of the patients was 4.6 years (range: 3 months to 9 years) years. Ectopic adrenal nodules were localized in the spermatic cord, in the vicinity of the epididymis and appendix testis, on the epididymis, and on the tunica albuginea of an atrophic testis undergoing orchiectomy due to intraabdominal localization. Adrenal cortex cells were found in 5 patients, and both cortex and medullar cells were found in 1 patient. No malign transformation was detected. Hormonal, biochemical, hematologic, and urinary analyses did not yield any significant results. Conclusion: Inguinoscrotal ectopic adrenal tissues are incidentally detected lesions during surgical interventions. They are benign lesions associated with no significant symptoms. Nevertheless, it is considered to be of benefit to remove these tissues in order to perform histopathological evaluation for differential diagnosis.