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Öğe Are sinus-track cultures reliable for identifying the causative agent in chronic osteomyelitis?(Springer, 2009) Ulug, Mehmet; Ayaz, Celal; Celen, Mustafa Kemal; Geyik, Mehmet Faruk; Hosoglu, Salih; Necmioglu, SerdarThe infection of bone that contains bone marrow called osteomyelitis, and is caused by different microorganisms. In this study, we aimed to determine the diagnostic value and accuracy of cultures of material from a sinus track compared with those of cultures of bone specimens that have been controversial. Prospective study was conducted at Hospital University of Dicle, a 1,090-bed university-based hospital located in DiyarbakA +/- r, Turkey. Between May 2005 and September 2006, sinus-track cultures were compared with those of bone cultures from 43 patients with chronic osteomyelitis. The patients' mean age was 30.6 +/- A 3.6 years, and 29 (67%) male and 14 (33%) female. Organisms isolated from bone cultures were Staphylococcus 69% (29/42), Escherichia coli 9.5% (4/42), Pseudomonas aeruginosa 9.5% (4/42), Proteus mirabilis 7% (3/42), respectively. Cultures of sinus track and bone specimens gave identical results in 38% of patients. The value of bone culture in the therapy of osteomyelitis must be emphasized; it is the only reliable means of determining the responsible agent, up on which the antibiotic therapy is based. The correlation between sinus track and bone cultures was 38%, i.e., failure in the treatment for 6 patients out of 10.Öğe Clinical and radiological results of posterior instrumentation without fusion for thoracolumbar fractures(Academic Journals, 2011) Sargin, Serdar; Ucar, Bekir Yavuz; Necmioglu, Serdar; Bulut, Mehmet; Gem, MehmetA retrospective study of clinical and radiological results of nonfusion operative treatment for thoracolumbar fractures. In this study, we aimed to demonstrate that fusion was not always required in the surgical treatment with posterior instrumentation for thoracolumbar vertebral fractures and to show the success of surgical treatment without fusion. Fusion was added considering failure of the implant and inability to maintain the corrected kyposis angle after posterior instrumentation for thoracolumbar vertebral fractures. Fusion related problems such as the fusion-induced loss of stability in posterior elements, graft donor site problems, increased blood loss, allograft associated infections, and prolonged operation time, focus attention on surgical treatment without fusion. We intended to demonstrate the alignment and stability of the spine in the coronal and sagittal planes after treatment without fusion. Kyphosis angle and the extent of the collapse were measured in preoperative, postoperative and final examination films of 60 patients with thoracolumbar vertebral fractures. Based on the computerized tomography and magnetic resonance images of the patients, we evaluated intracanal fragments, the presence of pedicle and laminar fractures, posterior ligamentous complex status and the presence of medullary edema. With an aim to evaluate pain and quality of life of the patients, the oswestry disability index (ODI) and Roland morris disability questionnairre were tested. The obtained results were evaluated and the final postoperative conditions of the patients were investigated. For the statistical analysis of local kyphosis angle, sagittal index and percentage of anterior collapse that were measured in preoperative, postoperative and final examinations of the patients, descriptive analysis and one way analysis of variance for related samples were conducted. And Pearson's correlation test was used for the analysis of the relationship between radiological measurements and clinical functions. It can be concluded that the patients derived radiological and statistically significant benefit from the surgery in terms of restoration of anterior column height and that postoperative radiological values were maintained with minimal reduction until the final examination (p>0.05) and that the surgery was effective in remodeling of the vertebral body. When evaluated in terms of the clinical results, a negative relationship (r = 0.300) between Oswestry scores and percentage of anterior collapse was found to be statistically significant (p<0.05). Our findings that the patients derived statistically significant benefit radiologically, in terms of local kyphosis angle and sagittal index correction from the posterior instrumentation without fusion and that postoperative radiological values were maintained with minimal increase (p>0.05) until the final examination, support our conclusion that fusion is not required. Hence, we can eliminate complications of fusion surgery.Öğe Clinical and radiological results of posterior instrumentation without fusion for thoracolumbar fractures(Academic Journals, 2011) Sargin, Serdar; Ucar, Bekir Yavuz; Necmioglu, Serdar; Bulut, Mehmet; Gem, MehmetA retrospective study of clinical and radiological results of nonfusion operative treatment for thoracolumbar fractures. In this study, we aimed to demonstrate that fusion was not always required in the surgical treatment with posterior instrumentation for thoracolumbar vertebral fractures and to show the success of surgical treatment without fusion. Fusion was added considering failure of the implant and inability to maintain the corrected kyposis angle after posterior instrumentation for thoracolumbar vertebral fractures. Fusion related problems such as the fusion-induced loss of stability in posterior elements, graft donor site problems, increased blood loss, allograft associated infections, and prolonged operation time, focus attention on surgical treatment without fusion. We intended to demonstrate the alignment and stability of the spine in the coronal and sagittal planes after treatment without fusion. Kyphosis angle and the extent of the collapse were measured in preoperative, postoperative and final examination films of 60 patients with thoracolumbar vertebral fractures. Based on the computerized tomography and magnetic resonance images of the patients, we evaluated intracanal fragments, the presence of pedicle and laminar fractures, posterior ligamentous complex status and the presence of medullary edema. With an aim to evaluate pain and quality of life of the patients, the oswestry disability index (ODI) and Roland morris disability questionnairre were tested. The obtained results were evaluated and the final postoperative conditions of the patients were investigated. For the statistical analysis of local kyphosis angle, sagittal index and percentage of anterior collapse that were measured in preoperative, postoperative and final examinations of the patients, descriptive analysis and one way analysis of variance for related samples were conducted. And Pearson's correlation test was used for the analysis of the relationship between radiological measurements and clinical functions. It can be concluded that the patients derived radiological and statistically significant benefit from the surgery in terms of restoration of anterior column height and that postoperative radiological values were maintained with minimal reduction until the final examination (p>0.05) and that the surgery was effective in remodeling of the vertebral body. When evaluated in terms of the clinical results, a negative relationship (r = 0.300) between Oswestry scores and percentage of anterior collapse was found to be statistically significant (p<0.05). Our findings that the patients derived statistically significant benefit radiologically, in terms of local kyphosis angle and sagittal index correction from the posterior instrumentation without fusion and that postoperative radiological values were maintained with minimal increase (p>0.05) until the final examination, support our conclusion that fusion is not required. Hence, we can eliminate complications of fusion surgery.Öğe The Diagnostic Value of Sinus-Track Cultures in Secondary Pediatric Chronic Osteomyelitis(Kuwait Medical Assoc, 2011) Ulug, Mehmet; Ayaz, Celal; Celen, Mustafa Kemal; Necmioglu, SerdarObjective: To determine and compare the diagnostic value and accuracy of culture of material from a sinus track with culture of material from bone specimens Design: Retrospective study Setting: Dicle University Medical School and Batman State Hospital, Turkey Subjects: Twenty-one patients with secondary chronic osteomyelitis (COM). Material for culture was taken from the sinus as well as the bone specimens Interventions: Surgery for COM Main outcome measures: The diagnostic value of sinus track culture Results: The mean age of patients was 8.5 +/- 3.8 years. 15 (71.4%) were male and six (28.6%) were female. Organisms isolated from bone cultures were Staphylococcus 71.4% (15 / 21), Pseudomonas aeruginosa 9.5% (2 / 21), Escherichia coli 9.5% (2 / 21), Proteus mirabilis 4.8% (1 / 21), Klebsiella pneumoniae 4.8% (1 / 21), respectively. Cultures of sinus track material and bone specimens gave identical results in 47.6% of patients. Conclusion: This study shows that if treatment of COM was planned according to the microbiological analysis of material from the sinus-track, it may not result in recovery every time. We found approximately 48% concordance between sinus-track and bone cultures. In other words, antimicrobial therapy guided by antibiograms of bacteria isolated from sinus-track would be inappropriate in 52% of patients with COM and result in treatment failure.Öğe Gaucher's Disease Presenting with Massive Hepatic Fibrosis and Skeletal Abnormalities: A Case Report with Review of the Literature(Ortadogu Ad Pres & Publ Co, 2011) Yalcin, Kendal; Ucmak, Feyzullah; Bestas, Remzi; Unal, Hakan Umit; Necmioglu, Serdar; Mizrak, BulentThe case presented in this manuscript is a 32-year-old female referred to our clinic with massive hepatosplenomegaly, thrombocytopenia, anemia and avascular necrosis at the head of right femur. Gaucher's disease was diagnosed upon observation of specific blood cells in bone marrow and liver. Homozygote N370S mutation was established in the Gaucher's mutation screening. Glycocerebrosidase enzyme level of the patient was quite low (0.66 nmol/hour/mg). Additionally, histological examination of the liver revealed massive hepatic fibrosis without any clinically significant signs of cirrhosis or portal hypertension. Other significant signs of the patient were severe skeletal involvement with stage V/c avascular necrosis of the femoral head and Erlenmeyer flask paralysis. Glycocerebrosidase enzyme replacement therapy was initiated at 60 units/kg after the diagnosis was established. The case presented here is a female patient with signs of hepatic, bone marrow and skeletal system involvement. This rare non-neuropathic type 1 Gaucher's case with massive hepatic fibrosis and pathogonomic skeletal signs has been evaluated in the light of literature.Öğe Is varus osteotomy necessary in one-stage treatment of developmental dislocation of the hip in older children?(British Editorial Soc Bone Joint Surgery, 2007) Arslan, Huseyin; Kapukaya, Ahmet; Bekler, H. Ibrahim; Necmioglu, SerdarPurpose Innominate osteotomy, varisation-derotation osteotomy, and shortening osteotomy are the most common surgical procedures used to achieve pelvifemoral realignment in the treatment of children over three years of age with developmental hip dislocation. It is well known that varus osteotomy can improve the acetabular index but it does have some disadvantages. The aim of this study was to discuss the results obtained with patients treated only with Salter osteotomy, derotation osteotomy, and shortening, without varus osteotomy, and to evaluate the need for varisation on the basis of these results. Methods Between 1996 and 2001, twenty-four hips, sixteen unilateral and four bilateral, of a total of twenty patients treated with this method and available for final controls were evaluated. The study included sixteen female and four male patients with a mean age of 4 years 2 months (ranging between 2 years 10 months and 8 years). The mean follow-up period was determined as 6.57 years (range 5-10 years). McKay's clinical criteria, Sever's radiological criteria, and the evaluation system modified by Trevor et al. were used for evaluation of the results. Results Based on McKay's clinical criteria, eighteen hips (75%) were classified as type I, four hips (16%) as type II, and two hips (9%) as type III. According to Sever's radiological criteria, thirteen hips (54%) were graded as grade I, nine hips (37.5%) as grade II, and two (8.5%) as grade III. According to the modified evaluation system of Trevor et al. the results were categorized as excellent in thirteen hips, good in nine hips, and moderate in two hips. Pre-operative mean acetabular index was measured as 37.3 degrees (28 degrees-50 degrees) and early post-operative mean acetabular index as 26 degrees (18 degrees-38 degrees). In the final radiological examination the mean acetabular index was measured as 18.3 degrees and the mean CE angle as 30.1 degrees (15 degrees-38 degrees). Avascular necrosis affecting the results developed in five hips. Conclusion It is concluded that in older children with developmental dislocation of the hip (DDH) treated with one-stage combined surgical intervention, adequately stable concentric reduction can be achieved without varisation and that varus osteotomy is not always necessary.Öğe Open Ankle Dislocations Without Associated Fracture(Sage Publications Inc, 2012) Ucar, Bekir Yavuz; Necmioglu, Serdar; Bulut, Mehmet; Azboy, Ibrahim; Demirtas, AbdullahBackground: This study aimed to clarify the intermediate followup results of reduction without soft tissue repair in open ankle dislocations without fracture. Methods: We retrospectively reviewed cases of open isolated ankle dislocations without associated fracture. Five male patients treated between January 2005 and July 2009 were enrolled in this study. Debridement and reduction with primary wound closure of the skin were performed without suture of the capsule or repair of the ligaments. The outcome was evaluated by the American Orthopaedic Foot & Ankle Society score (AOFAS). The time period for returning to previous level of activity was also recorded. Results: The average age of the patients was 34 (range, 27 to 44) years, and the average followup was 4 (range, 2 to 6) years. The average of the last control AOFAS score was 90 (range, 84 to 98) points. Two ankles were rated as excellent, and the other three were rated as good. Patients returned to their previous levels of physical activity at an average of 9 weeks. Conclusion: Favorable long-term results were obtained for reduction without ligament repair in pure ankle dislocations.Öğe Post therapeutic lower extremity rotational profiles in children with DDH(British Editorial Soc Bone Joint Surgery, 2008) Arslan, Huseyin; Ersoz, Huseyin; Kisin, Bulent; Kapukaya, Ahmet; Necmioglu, SerdarPurpose The purpose of this study was to investigate post-therapeutic lower extremity rotational profiles in children with developmental dislocation of the hip (DDH), the differences between these values and those of normal children, and the relationship between these differences and clinical and radiological results. Methods In 82 lower extremities of 64 patients, the footprogression angle was measured clinically and the transmalleolar axis angle photographically, and hip rotations and thigh-foot angle were measured both clinically and photographically. The data obtained were compared with Staheli's data for normal children. In addition, clinical and radiographic data were compared within subgroups and with Staheli's data. Student's t-test and one-way ANOVA were used for statistical evaluation. Results The medial rotation of the hip, the average clinical value was 44.668, and the photographic value was 42.288. Lateral rotation of the hip, the average clinical value was 38.018, and the average photographic value was 37.298. Thigh-foot angle, his angle was clinically 8.238 and photographically 9.688. Angle of the transmalleolar axis, the photographic average was 21.598. Foot-progression angle, the clinical average was 10.708. It was determined that the lower extremity rotational profiles of children with DDH treated after walking did not differ from those of normal children, but that the internal and external hip rotations of McKay type III and IV patients were below those of normal children and of McKay type I and II patients. Conclusion Lower extremity rotational profiles in children with DDH who received appropriate treatment were the same as those for normal children.Öğe Treatment of intertrochanteric femur fractures with 95A° fixed-angle blade plate in elderly patients(Springer, 2010) Kesemenli, Cumhur Cevdet; Memisoglu, Kaya; Necmioglu, Serdar; Kayikci, CumaIn this study, we aimed to evaluate the results of treatment of intertrochanteric femur fractures fixation with a 95A degrees fixed-angle blade plate in elderly patients. Fifty-eight patients with intertrochanteric femoral fractures were treated with 95A(0) fixed-angle blade plate. There were 32 female and 26 male patients. The fractures resulted from a simple fall in 42 patients, a motor vehicle accident in 6, and a fall from a height in 10 patients. The mean clinical follow-up was 27 months. Clinical outcomes were evaluated according to the American Academy of Orthopeadic Surgeons' criteria. Shortening greater than 2 cm was noted in these patients at last follow-up as a result of varus malunion, plate bending developed only in 3 patients, and the loss of reduction developed in two patients, but reoperation was not needed. According to these criteria, results were poor in 2 patients, fair in 6, good in 16 and excellent in 31 patients. Consequently, 95A degrees fixed-angle blade plates could be thought as a proper alternative technique due to their easy applicability, low learning curve and complication rates.