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Öğe Audiological Findings in Acromegaly Patients(Mediterranean Soc Otology & Audiology, 2011) Baylan, Muzeyyen Yildirim; Gokalp, Deniz; Celik, Yusuf; Tuzcu, Alpaslan; Meric, Faruk; Topcu, IsmailObjective: The aim of this study was to evaluate otologic problems in patients with acromegaly. Materials and Methods: This retrospective study was performed on 26 patients with acromegaly and 27 age-matched healthy controls. Otoscopic examination, pure tone odiometry, tympanometry, otoacoustic emissions, and stapes reflex were performed in all cases. Hearing thresholds of air and bone conduction (AC and BC), middle ear function, cochlear function, tympanic membrane compliance, gradient, peak pressure, and external ear canal volume were researched in patients with acromegaly. Results: The hearing thresholds for all frequencies except Right-AC 4000 frequencies were found to be significantly higher in patients with acromegaly as compared to the control group (p<0.05). Also significant correlation coefficients were calculated among disease duration, hearing thresholds, and tympanometric variables (p<0.05). There was a significant difference in tympanometry results between the two groups in regard to external ear canal volumes of the right and left ears (p <= 0.05). No differences were observed between the two groups in their type of tympanometry, stapes reflex, and otoacoustic emissions (OAE) (p>0.05). Conclusions: We have determined that patients with acromegaly have lower levels of hearing in both bone and air conduction compared with the normal population. This may be ascribed to deformation of hearing physiology related to hypertrophy in the temporal bone.Öğe Congenital os vomer agenesis: Case report and literature review(Vendome Group Llc, 2012) Yorgancilar, Ediz; Yildirim, Muzeyyen; Gun, Ramazan; Meric, Faruk; Topcu, IsmailDefects of the nasal septum occur as a result of a variety of causes, including tuberculosis, irritation, neoplasia, trauma, infection, and chronic inflammatory diseases. Congenital os vomer agenesis as a cause is very rare. We report the case of a 28-year-old man with a defect in the posteroinferior part of the nasal septum that was discovered incidentally during a routine endoscopic examination. The patient was diagnosed with congenital os vomer agenesis, and the diagnosis was confirmed by computed tomography We discuss the features of this case and review the literature on this rare anomaly.Öğe Does Radiofrequency Exposure Affect Hearing of Children?(Aves, 2009) Meric, Faruk; Dasdag, Suleyman; Dasdag, M. MutluObjective: The effects of radio frequency (RF) and microwave radiation on humans have been the subjects of continuous investigation. Since one of the major group of children exposed to RF/microwave radiation includes those living in the employee residential houses of radio broadcasting station, this study investigates whether RF affects auditory systems of children living in the houses close to a 1,062 kHz medium wave radio broadcasting station. Materials and Methods: The study is carried out on twenty-five volunteer children (Boys: 13, Girls: 12) living in employee residential houses close to a broadcasting stations. All subjects in the control group were similar in age, socioeconomic status, but they were not exposed to radiofrequencies. Brainstem Evoked Response Audiometer (BERA) and Pure Tone Audiometry (PTA) were used to measure the effects of RF under investigation on hearing thresholds of the subjects. I-III, III-V and IN inter peak intervals were measured in BERA. Hearing thresholds at 250 Hz, 500 Hz, 1,000 Hz, 2,000 Hz, 4,000 Hz and 8,000 Hz were measured in pure tone audiometric measurement. Results: Statistically insignificant sensory neural hearing loss was observed in six children living in residence of broadcasting station at 4,000 and 8,000 Hz frequencies (p > 0.05). However, no difference was observed between the children in the residence of broadcasting station and control (p>0.05). BERA results also indicated no significant differences (p>0.05). Conclusion: Our results showed no actual hearing loss in the RF exposed children living in employee residential houses. However, we suggest monitoring of hearing function.Öğe EFFECT OF EXTREMELY LOW FREQUENCY MAGNETIC FIELD AND MOBILE PHONE EXPOSURE ON NASAL MUCOSA AND NOSE SKIN(Diagnosis Press Ltd, 2011) Dasdag, Suleyman; Akdag, Mehmet Zulkuf; Meric, Faruk; Uzunlar, Ali Kemal; Celik, Mustafa Salih; Gun, RamazanThe increasing usage of wireless comunication systems and electric-electronical systems in daily life has caused a concern over possible adverse effects of radio frequency radiation (RFR) and Extremely Low Frequency Magnetic Fields (ELF-MF) on biological systems. The aim of the study was to investigate the long-term effect of 900 MHz RFR and ELF-MF exposure on nasal mucosa and nose skin of rats. In this study two different exposure systems were used to get information about the effects of RFR emitted from mobile phones and ELF-MF on nose. In the first part of the study Twenty one Wistar Albino adult male rats (sham: 7, exposure: 14) were used to determine the effects of 900 MHz RFR on nose. For the exposure group, rat heads were exposed to the 900 MHz RFR 2 h per day (7 days in a week) for 10 months. For the sham group, same process was applied to the rats, except that the generator was turned off In the second part of the study 30 male Sprague-Dawley rats (Mona: 10, first exposure: 10, second exposure: 10) were used to determine the effects of 100 mu T and 500 mu T extremely low frequency magnetic field (ELF-MF) which complies to the safety standards for public and occupational exposure. The rats in the exposure groups of this part of the study were exposed to 100 mu T and 500 mu T ELF-MF for 2 hours per day (7 days in a week) during 10 months in a Plexiglas cage. For the sham group, the same experimental process was applied to the rats but ELF-MF generator was turned off The results of the present study showed that 10 months of exposures of mobile phones and ELF-MF do not affect the mucous membrane and skin of nose. In conclusion, radiofrequency and ELF-MF used in this study do not affect nasal skin and mucosa of rats exposed to 900 MHz RFR, 100 mu T and 500 mu T ELF-MF.Öğe Histopathological Evaluation of the Polyps with and without the Presence Cholesteatoma(Aves, 2010) Baylan, Muzeyyen Yildirim; Koc, Ersar Evren; Kilic, Nihal; Meric, FarukObjective: To determine if there were any differences between the histopathological structures of the polyps with or without cholesteatoma Materials and Methods: In our study, 41 patients underwent operation with complaints of chronic otitis media with polyp. The patients were divided into those who had cholesteatoma and those who did not, so that discriminatory features were identified. Chronic otitis media with polyp was associated with cholesteatoma in 21 patients. Cholesteatoma was not found in 20 patients with chronic otitis media with polyp. Specimens removed from the both of patients groups were evaluated and compared between the groups in according to histopathologic features. Results: We observed that specimens of polyps with cholesteatoma were comprised of keratinized masses, keratinized tissue layers, and abundant immature granulation tissue, whereas, specimens of the polyps without cholesteatoma consisted of copious glandular stroma bordered by smooth epithelium (p<0,05). Conclusion: Our study showed that histopathologic features of the polyps suggest the presence or absence of cholesteatoma.Öğe LONG-TERM EFFECT OF 900 MHz RADIOFREQUENCY RADIATION EXPOSURE ON COCHLEAR FUNCTIONS(Taylor & Francis Ltd, 2012) Yorgancilar, Ediz; Dasdag, Suleyman; Akdag, Mehmet Zulkuf; Gun, Ramazan; Meric, FarukThe purpose of this study was to investigate the effect of 900 MHz radiofrequency radiation on the cochlear function. Fourteen Wistar albino adult male rats were equally divided into two groups: sham control and exposure groups. Rat heads in the carousel were exposed to 900 MHz microwave radiation (power output: 2 W) emitted from generator The rats in the study group were exposed to the radiofrequency radiation 3 h per day (7 days a week) for 6 months. For the sham group, the same procedure was applied to the rats (3 h per day, 7 days a week for 6 months), except that the generator was turned off Distortion Product Otoacoustic Emissions (DPOAE) values of rats were measured at the beginning of the study (baseline), 3rd and 6th month of the exposure. There were no significant DPOAE changes either in the exposure or sham control groups (P > 0.05). In conclusion, according to the results for the DPOAE values obtained in this study we can state that long-term exposure to 900 MHz radiofrequency radiation, which is 3 h a day (during 6 months), did not affect the cochlear function of rats. However, the DPOAE values obtained in this study do not constitute an example for subjects who talk on the mobile phone for a long time. Biotechnol. & Biotechnol. Eq. 2012, 26(6), 3397-3401Öğe Long-term effect of radiofrequency turbinoplasty in nasal obstruction(Taylor & Francis Ltd, 2014) Akdag, Mehmet; Dasdag, Suleyman; Ozkurt, Fazil Emre; Celik, Mehmet Yusuf; Degirmenci, Aydin; Demir, Huseyin; Meric, FarukThe aim of this retrospective study is to investigate long term (two years) effect of radiofrequency tissue volume reduction (RFVTR) on nasal obstruction associated with inferior turbinate hypertrophy, which is not respond to medical treatment. This retrospective study carried out on 98 patients with nasal obstruction treated by RFVTR (56 males, 42 females, from 17 to 70 years of age). Visual analogue scales (VAS) and nasal endoscopic view score (NES) were used for nasal obstruction to evaluate the efficacy of the treatment. Results of one, three, six, twelve and twenty four months after RFVTR treatment were compared with pre-exposure values. Turbinate edema and nasal obstruction in the treated patients were recovered after one month of treatment (p < 0.01). Maximum improvement were determined at the end of third month (p < 0.01). However, eficacy of RFVTR declined twelve months after treatment. Final percentage of imrovement was found as 51 % at the end of second year of treatment because of co-factors was not eliminated by some patients. On the other hand, no statistical significant difference was observed between the right and left nasal cavity (p < 0.001). In conclusion, the result of this study indicated that patients who have not eliminate co-factors such as smoking, obesity and allergic rhinitis may need re-application of RFTVR. However, further studies on radiofrequecy energy level and elimination of other co-factors are necessary to illuminate the eficacy of RFVTR.Öğe Middle Ear Pressure and Factors Affecting It in Intubated Patients Hospitalized in Intensive Care(Galenos Yayincilik, 2014) Akdag, Mehmet; Cetin, Muzeyyen; Baysal, Zeynep Yildirim; Kadiroglu, Ali Kemal; Celik, Mehmet Yusuf; Meric, FarukObjective: To assess the probable agents affecting middle ear pressure in intubated patients hospitalized in intensive care units with various diagnoses. Methods: Middle ear pressure of 38 patients hospitalized in intensive care units within our faculty hospital was measured using portable tympanograms and acoustic reflectometry. The mode of the device to which each patient was attached and patients' blood pressure, Glasgow Coma Score, and additional disease parameters other than admission diagnosis were recorded. All data collected were subjected to statistical analysis to determine whether or not they affected middle ear pressure. Results: Septal deviation, survey, and mode of automatic respiratory device emerged as factors affecting middle ear pressure (odds coefficient 4.796, 3.745, 2.557, respectively, with 95% CI). Although aged over 60, additional disease and nasogastric tube also compromised middle ear pressure; the levels involved were not statistically significant. Conclusion: Middle ear pressure in patients hospitalized in intensive care units may change, particularly after the seventh day. This may particularly involve septal deviation, survey, and mode of automatic respiratory device, and tympanograms and reflectometry may be added to the patient-monitoring protocol in terms of changes in middle ear pressure.Öğe Prevalence and risk factors of otitis media with effusion in primary school and kindergarten children in provincial and district centers of Diyarbakir(Deomed Publ, Istanbul, 2012) Guzel, Recep; Meric, Faruk; Toprak, Serdar Ferit; Yorgancilar, Argun Ediz; Gun, RamazanObjective: The aim of the present study was to determine the prevalence of otitis media with effusion (OME) among primary school and kindergarten children in provincial and district centers of Diyarbakir. Methods: The study was conducted at 4 primary schools and 3 kindergartens in the city center, and at 13 primary schools in district centers. Using the combined physical examination and otoscopic and tympano-metric evaluations, 256 children out of 1,763 (14.5%) were diagnosed with OME. Results: Among total OME cases (119 girls, 137 boys) 118 (46.1%) had bilateral while 138 cases (53.9%) had unilateral effusion (89 on left and 49 on right ear). The prevalence of OME among primary school students were 12.6% at the city center, 16.3% at district level schools and 15.2% among kindergarten students. Higher OME prevalence is associated with passive smoking and allergic rhinitis. Age, sex, attending kindergarten and socioeconomic status were not significantly related with OME. Conclusion: In conclusion, because of high prevalence of otitis media and its possible severe complications screening equipment should be ensured at primary level health institutions. Screening for OME should be a part of preventive health services particularly for all kindergarten and early elementary school students; and should be performed by ENT specialist or pediatricians/general practitioners trained in pneumatic otoscopic and tympanometric evaluation.Öğe Radiologic and Surgical Findings in Chronic Suppurative Otitis Media(Lippincott Williams & Wilkins, 2014) Gul, Aylin; Akdag, Mehmet; Kinis, Vefa; Yilmaz, Beyhan; Sengul, Engin; Teke, Memik; Meric, FarukOur aim in this study was to evaluate the efficiency of preoperative temporal bone computed tomography (CT) in detecting pathologic conditions in patients with chronic suppurative otitis media (CSOM). The intraoperative findings and temporal bone CT results of 350 patients who were diagnosed with CSOM between September 1, 2010, and June 1, 2013, were compared. Comparison parameters were as follows: the presence of cholesteatoma, erosion of the outer ear bone canal, erosion of the middle ear chain, erosion of the dural plate, erosion of the lateral semicircular canal, erosion of the sigmoid sinus wall, and dehiscence of the facial canal. The contribution of CT was limited in showing the outer ear canal destruction, dural plate destruction, facial canal destruction, lateral semicircular canal destruction, and destruction of the sigmoid sinus wall. However, CTwas more sensitive in detecting cholesteatoma and erosion of the ossicular chain. These results indicate that preoperative CT of patients with CSOM serves as an important guide for otolaryngologists, although there are limitations in the evaluation of the CT results.Öğe Thyroid Nodule Demonstrating Itself as Calcified Lung Lesion(Derman Medical Publ, 2010) Yorgancilar, Ediz; Yildirim, Muzeyyen; Gun, Ramazan; Meric, Faruk; Topcu, IsmailMultinodular goiter (MNG) is the most prevalent thyroid pathology. Thyroid gland enlarge as a result of MNG, the initial extension is typically outward. After this cervical enlargement, expansion may extend in to the mediastinum. As substernal goiters enlarge within the mediastinum, vascular and visceral structures may slowly became compressed. The most common symptoms of substernal goiter result from compression of the trachea and/ or esophagus and include dyspnea, choking sensation, cough, and dysphagia. Progressive hoarseness and superior vena cava syndrome are less common symptoms. Substernal goiters can remain asymptomatic for many years and it may be diagnosed incidentally. For example, routine chest radiography may reveal a mediastinal mass or tracheal deviation. Many authors have advocated surgical removal of all substernal goiters, even when these goiters are asymptomatic. In this article, we report a case of substernal MNG which demonstrating itself as a nodular calcification on chest X-Ray radiography.
