Yazar "Kurt D." seçeneğine göre listele
Listeleniyor 1 - 8 / 8
Sayfa Başına Sonuç
Sıralama seçenekleri
Öğe Comparison of Pelargonium sidoides, placebo and antibiotic treatment of chronic endometritis in dairy cows: A field trial(2009) Bademkiran S.; Kurt D.; Yokus B.; Celik R.We compared the effects of the intrauterine application of an extract of Pelargonium sidoides (EPs 7630) to parenteral antibiotic injection in the treatment of chronic endometritis, which is commonly encountered postpartum in cows. Forty six cows diagnosed with chronic endometritis 21-27 days postpartum were selected and divided into 3 groups. Cows in Group I (n = 16) received a physiological parenteral injection of 10 mL of serum per day for 3 days. Similarly, cows in Group II (n = 15) received 1 mg kg-1 ceftiofur (Ceftivil®) parenterally. Those in Group III (n = 15) received an 8 mg (10 mL)/cow intrauterine dose of EPs 7630 (Umca®) for 3 days. When examined between the 35th and 41st day, clinical recovery rates were found to be as follows: for Group 1,1/16 (6.2%); for Group II, 8/15 (53.3%) and for Group II, 4/15 (26.69%). After this examination, cows whose chronic entrometritis symptoms persisted according to clinical and rectal examination received a further 3 days of the treatment appropriate to their group. Later on various parameters were identified thus, for Groups I-III, respectively: insemination rate 87.5, 66.6 and 93.3%; days to 1st service 103.5, 91.0 and 96.0; 1st service conception rate 28.5, 40.0 and 35.7%; days open 140,120 and l31 and cows pregnant within 250 DIM 56.25, 80.0 and 66.6%. © Medwell Journals, 2009.Öğe The effect of exogen glutathione administration on the gastric mucosal barrier in rats under stress(1998) Kanay Z.; Sert C.; Isik B.; Kurt D.; Guzel C.; Mete N.We investigated the effect of glutathione (GSH) on the gastric mucosal barrier of rats under stress. Twenty two swiss Albino rats weighing between 150-200 g were used and stress was induced by cold and immobilisation. GSH was administered in 300 mg/kg doses to the study group and oral saline was given to a control group. Mucus and phospholipid levels of the gastric mucosal barrier were then measured using come and Baur's methods. These important components of the gastric mucosal barrier were found to be decreased (p<0.05), but levels were higher in rats given GSH than in the control group (p<0.01, p<0.05 respectively). To conclude, GSH was found to be effective in preventing gastric mucosal barrier damage caused by stress.Öğe The effects of age and gender on some biochemical serum parameters in Zom sheep raised in the vicinity of Karacadağ(Israel Veterinary Medical Association, 2015) Durak M.H.; Erkan R.E.C.; Çelik R.; Yokuş B.; Kurt D.; Gürgöze S.A hundred and seventy three clinically healthy Zom sheep aged 1-6 years and grazed on grassland under similar conditions in six villages of the Karacadağ and Ovabağ towns of the central, Bismil and Çınar districts of Diyarbakır province. The effect of gender in the evaluation for serum glucose, ?~glutamyltransferase, and alkaline phosphatase were observed for Zom sheep. The effect of age on the assessment made by taking into consideration the serum cholesterol, direct bilirubin, very low-density lipoprotein, alkaline phosphatase, ?~glutamyltransferase and direct bilirubin and high-density lipoprotein were also observed. In conclusion the age and gender of the Zom sheep needs to be taken into consideration in order to ensure an accurate clinical diagnosis and prognosis. © 2015, Israel Veterinary Medical Association. All rights reserved.Öğe Effects of lycopene and vitamine E administration over gastric mucosal damage induced by Aflatoxin B1(2009) Kurt D.; Saruhan B.G.; Yokus B.; Cakir D.U.In the present study, we aimed to determine, the changes induced by Aflatoxin B1 (AFBj) administration on rat gastric mucosal barrier and gastric mucins alongside revealing the protective effects of lycopene and Vit E. Thirty-five Wistar-Albino male rats weighing 180-220 g, were divided into 7 groups as to include 5 rats in each group: control, lycopene (10 mg/kg/day lycopene for 15 days (Lycopene 10% FS), AFB, (single dose of 2.5 mg AFBj kg-1 on the 12th day of the study), Lycopene + AFB1 (10 mg lycopene/kg/day for 15 days and single dose of 2.5 mg AFB1 kg-1 on the 12th day of the study) and Vitamin E + AFB1, (10 mg/kg/day Vitamin E for 15 days and single dose 2.5 mg AFB1, kg-1 on 12th day). Following the sacrifice of study subjects on the 15th day, gastric mucus and phospholipid levels were determined and their stomachs were examined histopathologically. Examination of mucus and phospholipid levels revealed a significant reduction in group 3-5, in which AFB1 has been applied (respectively, p<0.001, p<0.001). When lycopene and vitamine E groups are compared with the AFB1 group, a significant elevation was detected in mucus and phospholipid levels (respectively, p<0.001, p<0.001). Whereas, histopafhological examination of gastric mucosas of the aflatoxin group showed degenerative changes, gastric mucosas of the control group and the remaining study groups were normal. Histochemically, while neutral mucins were predominant in general structure of stomach, mixed and sialomucins were observed, as well. Particularly acid mucins with suplhate and periodate reactive acid mucins were found to be more predominant in the aflatoxin group compared to control and other groups. Histochemical features of mucins were observed to be consistent with specific functions of the different regions of stomach. Lycopene and vitamine E administrations were found to be protective against the damage induced by aflatoxin on gastric mucosa. © Medwell Journals, 2009.Öğe The effects of octreotide on gastric lesions and gastric mucosal barrier in rats which applied stress(1999) Guzel C.; Kanay Z.; Onen A.; Kurt D.; Denli O.; Canoruc F.The aim of this research was to investigate the effects of octreatide on gastric lesions and mucosal barrier in rats exposed cold +immobilisation stress. Twenty four Swiss Albino rats (approx 150-200 g) were used for this study. Feeds were witheld from to rats for 24 hours, after which they were divided in to three groups. Each group consisted of seven rats; I (n=7) non/stress-induced control group, 2 (n=7): cold and immobilisation stress was induced, 3 (n=7): 100 ?g/kg octreatide was administered subcutaneously one hour prior to stress induction. The rats were then killed and their stomachs examined for ulcerative lesions and ulcer indexes considered. The amounts of mucus and phospholipid, important components of the gastric mucosal barrier, were then rated using Corn and Baur methods and were found to be significantly decreased (p<0.05, p>0.05) in rats exposed to stress. In the third group given sandostatin, it was found that gastric lesions had been prevented. Moreover, mucus and phospholipid levels were higher in this group than the stress exposed control group. (p<0.05, p<0.05 respectively). According to our findings, octreatide is effective in preventing acute hemorrhagic gastric lesions caused by stress and in maintaining gastric mucosal barrier parameters.Öğe An Investigation of the Copper (Cu), Zinc (Zn) and Selenium (Se) Levels of Blood Serum and the Cu and Zn Levels of Wool of Akkaraman Ewes in the Diyarbakir Region(2001) Kurt D.; Denli O.; Kanay Z.; Güzel C.; Ceylan K.The aim of this study is to determine the copper, zinc and selenium levels of blood serum and the Cu and Zn levels of wool of healthy Akkaraman ewes grazed in the meadows in the Diyarbakir region. A total of 60 units of blood and wool samples from various villages in different counties of Diyarbakir (Bismil, Çinar, Ergani, Silvan, Kocaköy and some Diyarbakir villages) were studied. The Cu, Zn and Se levels of sera and the Cu and Zn levels of wool were analyzed by flameless atomic absorption spectrophotometer. We found significant differences in Cu and Se levels of sera, in Cu levels of wool (p<0.01) and in Zn levels of wool (p<0.05) in ewes from various counties, whereas no significant differences were observed in Zn levels of sera (p>0.05). Although there were considerable differences from county to county, the avarage values of these counties and herds that indicated the lowest values in respect to Cu and Zn contents were found to be either simillar to or just over the normal values. However, in the case of the selenium content, the average serum Se level of the Akkaraman ewes from various counties of Diyarbakir, except the central county, was found to be remarkably lower than the normal values. In the light of these findings, the rations of animals grazing in meadows are recommended to be reinforced with Se content.Öğe Protective effects of L-Arginine and pentoxifylline on mucosal barrier in ischemia-reperfusion induced gastric injury in rats(2003) Önen A.; Kanay Z.; Kurt D.Aim: To determine the effects L-Arginine (L-Arg) and pentoxifylline (Ptx) on mucosal barrier in ischemia-reperfusion (IR) induced gastric injury in rats. Method: Twenty-eight males, adult Wistar Albino rats (200-250 g) were used in the study. The rats were anesthetized by ketamine hydrokloride. Laparotomy only was applied in control group (n=7). In other three groups, coeliac artery was occluded for a period of 30 minutes followed by a reperfusion period of 60 minutes. No drug was given in IR group (n=7). In Ptx+IR group (n=7), 50 mg/kg Ptx was administered intraperitoneally before reperfusion. In L-Arg+IR group (n=7), 3 mg/kg/minute L-Arginine was increased immediately before refursion. The amounts of mucus and phospholipid were determined by Corne and Baur's methods. Ulcer index was measured via counting macroscopical petechial hemorrhage. Results: Mucus and phospholipid levels in gastric mucosa were significantly lower in IR group compared to control group (p<0.01). The amount of phospholipid was significantly higher in both Ptx+IR and L-Arg+IR groups when compared to those of IR group (p<0.01), while there were no significant differences between Ptx+IR and L-Arg+IR and IR group in terms of mucus amount (p>0.05). Phospholipid level was significantly higher in L-Arg+IR group when compared to Ptx+IR group (p<0.01), while there was no significant difference between these two groups from the point of mucus amount (p>0.05). Ulcer index was significantly higher in IR group than Ptx+IR and L-Arg+IR groups (p<0.05, p<0.01). Conclusion: Gastric IR breaks mucosal barrier through significantly decreased mucus and phospholipid levels and results in gastric mucosal damage via increased ulcer index. Ptx and L-Arg diminish barrier breakage and mucosal damage induced by IR. L-Arg seems to protect the gastric mucosal barrier better than Ptx does.Öğe Protective role of lycopene on aflatoxin B1 induced changes sperm characteristics and testicular damages in rats(2010) Taş M.; Güney Saruhan B.; Kurt D.; Yokuş B.; Denli M.The aim of this study was to investigate if lycopene could diminish the adverse effects of aflatoxin B1 (AFB1) on sperm characteristics, the testes, epididymis and oxidative stress in rats. A total of 28 adult male Wistar-Albino rats (8 weeks old weighing 180-220 g) were divided into four groups; Controls, lycopene treated rats (10 mg/kg BW, daily by gavage), AFB1 treated rats (2.5 mg/kg BW, single dose intra peritonal) and lycopene (10 mg/kg BW, daily by gavage) + AFB1 (2.5 mg/kg BW, single dose intra peritonal) treated rats. Traits of reproductive organs (testes and sperm characteristics, testicular histological findings and the testicular tissue oxidative status) were determined after 15 days of treatment. The sperm motility was significantly decreased while the rate of total abnormal sperms was significantly increased in rats treated with AFB1 alone compared to their levels in controls (P<0.001). The level of testes malondialdehyde (MDA) in rats treated with AFB1 was significantly higher than its level in controls (P<0.001). Treatment with AFB1 significantly decreased testes diameter and seminifer epithelium thickness (P<0.0001) when compared with the others. Similarly, the thickness of the germinative cell layer at seminifer tubul (ST) in rats treated with AFB1 was significantly smaller than controls. Treatment with lycopene significantly increased sperm motility (P<0.001) and alleviated the many negative effects of AFB1 on sperm characteristic and testicular damage in rats. In conclusion our results showed that consumption of 10 mg of lycopene/ BW given by gavage protected the rats to the toxicity of AFB1 when it is administrated as a single dose intraperitoneally.
