Yazar "Kurt, Dogan" seçeneğine göre listele

Listeleniyor 1 - 6 / 6
  • [ X ]
    Öğe
    Assessment of Serum Mineral and Certain Biochemical Variables in Self-Sucking Dairy Cows
    (Medwell Online, 2008) Bademkiran, Servet; Yokus, Beran; Icen, Hasan; Cakir, Dilek Ulker; Kurt, Dogan
    Self-sucking, that is, a cow sucking on her own teats is an important and leading cause of economic loss. However, the causes of self-sucking are virtually unknown, although numerous possible influencing factors, such as feeding management, nutrient deficits, genetic factors and housing systems have been suggested. In this study, our main objective was to investigate the possible effects of mineral levels on self-sucking in dairy cows. Biochemical variables of blood serum were also investigated. Cows which self-sucked had significantly lower serum concentrations of Mn, Co, Zn, P, Na, Cl, K and total protein, compared with the control group. Levels of serum cholesterol, HDL-C, LDL-C and ALP activity were significantly increased in the self-sucking group. There were no significant differences in serum levels of Ca, Mg, Cu, Fe, saturated Fe, iron binding capacity, urea, creatinin, uric acid, total bilirubin, amylase, gamaglutmyl transaminase, lactate dehidrogenase, creatin kinase, creatine kinase-MB, alanine transaminase and aspartate transaminase activities between the self-sucking group and the control group. The findings provide novel information about whether macro and micro element deficiency may cause self-sucking in dairy cows. An evaluation of our results supports the hypothesis that energy deficiency is a possible cause of self-sucking. Although the explanation is not clear, it may be related to decreased Co, Mn and P levels, which are important in carbohydrate and energy metabolism.
  • [ X ]
    Öğe
    Effect of ovariectomy and female sex hormones administration upon gastric ulceration induced by cold and immobility restraint stress
    (Saudi Med J, 2007) Kurt, Dogan; Saruhan, Berna G.; Kanay, Zeki; Yokus, Beran; Kanay, Berna E.; Unver, Ozkan; Hatipoglu, Savas
    Objective: To investigate the protective effects of estrogen and progesterone administrations on gastric mucosal barrier of rats applied ovariectomy, cold and immobility stress. Methods: Seventy female Wistar rats, obtained from Medical Science Application and Research Center, Dicle University, Turkey on the year 2004, were divided into 10 separate groups (n=7). Nothing was applied to the animals of Group 1 (control); bilateral ovariectomy was performed on the animals of the Groups 2, 4, 5, 6, 7, 8, 9, and 10. Groups 5 and 6 was applied 5 mg/kg 17beta-estradiol and groups 7 and 8 was applied 10 mg/kg progesterone for 7 days. The animals in the Groups 9 and 10 were applied 2.5 mg/kg 17beta-estradiol and 5 mg/g progesterone during 7 days. The animals in the groups 3, 4, 6, 8 and 1 were exposed to cold and immobility stress for 4 hours at 4 degrees C. Results: The levels of mucus and phospholipids were decreased in the rats applied ovariectomy and stress as compared to the control groups (p<0.001). The increase determined the mucus and phospholipids levels in estrogen and progesterone administered rats as compared to stress applied group (p<0.001). While the cold and immobility stress causes important damages in gastric mucosa, estrogen and progesterone administrations has protective effects in ovariectomized rats. Conclusion: The estrogen and progesterone administration prevents the stress that caused decrease in the levels of mucus and phospholipids, thus females are more resistant to gastric ulcer rather than males due to their sex hormones.
  • [ X ]
    Öğe
    Effects of Lycopene and Vitamine E Administration Over Gastric Mucosal Damage Induced by Aflatoxin B1
    (Medwell Online, 2009) Kurt, Dogan; Saruhan, Berna Guney; Yokus, Beran; Cakir, Dilek Ulker
    In the present study, we aimed to determine, the changes induced by Aflatoxin B-1 (AFB(1)) administration on rat gastric mucosal barrier and gastric mucins alongside revealing the protective effects of lycopene and Vit E. Thirty-five Wistar-Albino male rats weighing 180-220 g, were divided into 7 groups as to include 5 rats in each group: control, lycopene (10 mg/kg/day lycopene for 15 days (Lycopene 10% FS), AFB(1) (single dose of 2.5 mg AFB(1) kg(-1) on the 12th day of the study), Lycopene + AFB(1) (10 mg lycopene/kg/day for 15 days and single dose of 2.5 mg AFB(1) kg(-1) on the 12th day of the study) and Vitamin E + AFB(1) (10 mg/kg/day Vitamin E for 15 days and single dose 2.5 mg AFB(1) kg(-1) on 12th day). Following the sacrifice of study subjects on the 15th day, gastric mucus and phospholipid levels were determined and their stomachs were examined histopathologically. Examination of mucus and phospholipid levels revealed a significant reduction in group 3-5, in which AFB(1) has been applied (respectively, p<0.001, p<0.001). When lycopene and vitamine E groups are compared with the AFB(1) group, a significant elevation was detected in mucus and phospholipid levels (respectively, p<0.001, p<0.001). Whereas, histopathological examination of gastric mucosas of the aflatoxin group showed degenerative changes, gastric mucosas of the control group and the remaining study groups were normal. Histochemically, while neutral mucins were predominant in general structure of stomach, mixed and sialomucins were observed, as well. Particularly acid mucins with suplhate and periodate reactive acid mucins were found to be more predominant in the aflatoxin group compared to control and other groups. Histochemical features of mucins were observed to be consistent with specific functions of the different regions of stomach. Lycopene and vitamine E administrations were found to be protective against the damage induced by aflatoxin on gastric mucosa.
  • [ X ]
    Öğe
    Evaluation of synergic effects of iodixanol and trehalose on cryosurvival of electroejaculated ram semen
    (Wiley, 2020) Ozmen, Mehmet Ferit; Cirit, Umut; Arici, Ramazan; Demir, Kamber; Kurt, Dogan; Pabuccuoglu, Serhat; Ak, Kemal
    The primary aim of the study was to investigate whether iodixanol and trehalose would have a synergic effect on the cryosurvival of electroejaculated ram semen. Tris-based diluter was used to prepare 9 different extenders by the addition of iodixanol or trehalose alone or varying combinations of these substances. Diluters were prepared as follows: Tris (control), Io5 (5% iodixanol), Tr25 (25 mmol/L trehalose), Tr50 (50 mmol/L trehalose), Tr50 + Io1.25 (50 mmol/L trehalose and 1.25% iodixanol), Tr50 + Io2.5 (50 mmol/L trehalose and 2.5% iodixanol), Tr50 + Io5 (50 mmol/L trehalose and 5% iodixanol), Tr25 + Io5 (25 mmol/L trehalose and 5% iodixanol) and Tr12.5 + Io5 (12.5 mmol/L trehalose and 5% iodixanol). Supplementation of the freezing extender with trehalose or iodixanol alone supported the protection of both morphological and functional integrity of ram spermatozoa and total motility at 1 and 4 hr post-thawing respectively. However, beyond these positive effects, the combination of trehalose (25 mmol/L) and iodixanol (5%) significantly increased post-thaw sperm longevity and motion properties at the end of 4-hr incubation. The results of the study clearly showed that there was positive synergic effect of iodixanol and trehalose on cryosurvival of ram semen.
  • [ X ]
    Öğe
    Protective Role of Lycopene on Aflatoxin B1 Induced Changes Sperm Characteristics and Testicular Damages in Rats
    (Kafkas Univ, Veteriner Fakultesi Dergisi, 2010) Tas, Muzaffer; Saruhan, Berna Gueney; Kurt, Dogan; Yokus, Beran; Denli, Muzaffer
    The aim of this study was to investigate if lycopene could diminish the adverse effects of aflatoxin B-1 (AFB(1)) on sperm characteristics, the testes, epididymis and oxidative stress in rats. A total of 28 adult male Wistar-Albino rats (8 weeks old weighing 180-220 g) were divided into four groups; Controls, lycopene treated rats (10 mg/kg BW, daily by gavage), AFB(1) treated rats (2.5 mg/kg BW, single dose intra peritonal) and lycopene (10 mg/kg BW, daily by gavage) + AFB(1) (2.5 mg/kg BW, single dose intra peritonal) treated rats. Traits of reproductive organs (testes and sperm characteristics, testicular histological findings and the testicular tissue oxidative status) were determined after 15 days of treatment. The sperm motility was significantly decreased while the rate of total abnormal sperms was significantly increased in rats treated with AFB(1) alone compared to their levels in controls (P<0.001). The level of testes malondialdehyde (MDA) in rats treated with AFB(1) was significantly higher than its level in controls (P<0.001). Treatment with AFB(1) significantly decreased testes diameter and seminifer epithelium thickness (P<0.0001) when compared with the others. Similarly, the thickness of the germinative cell layer at seminifer tubul (ST) in rats treated with AFB(1) was significantly smaller than controls. Treatment with lycopene significantly increased sperm motility (P<0.001) and alleviated the many negative effects of AFB(1) on sperm characteristic and testicular damage in rats. In conclusion our results showed that consumption of 10 mg of lycopene/BW given by gavage protected the rats to the toxicity of AFB(1) when it is administrated as a single dose intraperitoneally.
  • [ X ]
    Öğe
    Serum Paraoxonase-1 Activity in Dairy Cattle and its Association with Dystocia
    (Medwell Online, 2008) Bademkiran, Servet; Yokus, Beran; Cakir, Dilek Ulker; Durak, Mehmer Hanifi; Kurt, Dogan
    The aim of this study was to investigate possible changes in the serum paraoxonase-1 (PON1) activity at the prepartum and postpartum stages in Holstein cows and to examine the relation between PON1 activity and dystocia. The 2nd objective of this study was to describe prepartum and postpartum serum concentrations of other relevant blood parameters and their associations with dystocia risk. Initially, 200 Holstein and 65 Holstein x Black home crosbreed cows, aged 3-8 year, were selected for this study. Samples were taken both in the 7th month of pregnancy and within the first 15 min postpartum. At the end of pregnancy, the cows were divided into two groups according to the type of birth: Difficult labour and normal labour. PON1 activities measured in the prepartum samples were significantly higher than in postpartum samples from cows which had normal or difficult labour. Although, PON1 activity from cows with dystocia was lower both pre-and postpartum, this difference did not reach statistical significance. Furthermore, there was a tendency to decreased PON1 activities in the case of absolute birth weight and twins. Evaluation of cholesterol, HDL-C, LDL-C, albumin, globulin and alkaline phosphatase levels does not appear to be useful in the assessment of dystocia. However, increased serum creatine kinase and creatine kinase isoenzyme MB may be a parameter which could be used in diagnosing dytocia in pregnancy.