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Öğe Combined use of low-dose bupivacaine, colloid preload and wrapping of the legs for preventing hypotension in spinal anaesthesia for caesarean section(Cambridge Med Publ, 2007) Kaya, S.; Karaman, H.; Erdogan, H.; Akyilmaz, A.; Turhanoglu, S.We tested the hypothesis that using a combination of methods would result in a greater reduction in the incidence of hypotension due to spinal anaesthesia in caesarean sections compared with using each method on its own. A total of 120 patients were randomly allocated to the following four treatment groups: 10 mg bupivacaine 0.5% intrathecally plus 500 ml Ringer lactate solution (group B); 4 mg bupivacaine 0.5% plus 25 mu g fentanyl plus 500 ml Ringer lactate solution (group F); 4 mg bupivacaine 0.5% plus 25 mu g fentanyl intrathecally plus 500 ml Gelofusine (R) intravenously (group G); and 4 mg bupivacaine 0.5% plus 25 mu g fentanyl intrathecally plus 500 ml Gelofusine (R) intravenously plus tight wrapping of the lower extremities with an Esmarch bandage (group E). The Esmarch bandage was only loosely applied in groups B, F and G. Hypotension was detected in 100% of the patients in group B compared with 70.0%, 46.7% and 23.3% of those in groups F, G and E, respectively. Hypotension was thus reduced by using a combination of several methods.Öğe EFFECT OF MOBILE PHONES ON TRACE ELEMENTS CONTENT IN RAT TEETH(Taylor & Francis Ltd, 2008) Adiguzel, O.; Dasdag, S.; Akdag, M. Z.; Erdogan, S.; Kaya, S.; Yavuz, I.; Kaya, F. A.Widespread use of wireless communication made it necessary to investigate the long term effect of mobile phone, which is the most popular technological equipment in the earth. One of the important parts of body that absorbs, radiation emitted from mobile phones is oral tissue. However mobile phone users and also scientists usually do not pay attention on effect of mobile phone e exposure on oral tissue. Therefore, there is no epidemiological and experimental studies focused on this part of body. The aim of this study was to investigate the of GSM (Global System for Mobile Communication) -Modulated 900 MHz radiofrequency radiation 017 trace element content of rat teeth. Thirty one Wistar Albino adult male rats were divided into three groups: experimental group (each, n=14), shame group (n=7), and cage control group (n=10). Head of the rats in the experimental group were & exposed to GSH-Modulated 900 MHz radiofrequency radiation for 2 hours per day during ten months. At the end of the exposure period, the contents of some trace elements as Ca, Mg, Zn, and P were measured in the oral tissue. The measurements were performed by Atomic Absorption Spectrophotometry (AAS). However phosphorus content of teeth was measured h.); ultraviolet spectrophotometer (UVS). Changes of Mg, and Zn contents in the experimental group were found to be statistically significant according to the sham and cage control groups. Ca and P contents in the (experimental group were higher than the sham and cage control groups. Difference between the groups was not statistically significant (p>0.05). The results of the study showed that GSM-Modulated 900 MHz radiofrequency radiation can be a factor to alter the teeth trace elements' densities. However further studies are necessary to know whether GSM-Modulated 900 MHz radiofrequency, radiations affects the oral tissues such as the teeth.Öğe The effects of extremly low frequency magnetic field and mangan to the oral tissues(Diagnosis Press Ltd, 2008) Kaya, S.; Celik, M. S.; Akdag, M. Z.; Adiguzel, O.; Yavuz, I.; Turnen, E. C.; Ulku, S. Z.Exposure to extremely low frequency magnetic field (ELFMF) originating from daily electrical-electronic appliances and electric lines, is a common thing. Recently, the discussions focused on the topic whether ELFMF had any harmful effects over health or not. Several previous studies displayed that ELFMF significantly increased bone mineral density. The aim of the present study was to investigate the influence of ELFMF and manganese over mineral accumulation in head and jaw bones of rats. Previous studies showed that manganese plays a significant role over normal development of enamel and dentin alongside contributing to the calcium and phosphorous association. In the present study, the effects of exposure to ELFMF and manganese on mineral density and histology of teeth, were investigated. In the present study, 64 male Wistar albino rats were divided into 8 groups. Amount of mineral elevations were determined in head and jaw bones of the first 6 groups (p <.05) and histologic alterations were found in teeth of rats. The obtained results indicated that ELFMF plays an important role over mineral density and histologic structure of cranial and jaw bones in rats. In conclusion, further epidemiological and experimental laboratory studies are required for more detailed evaluation of the effects of ELFMF on cranial and jaw bones of rats.Öğe Effects of Potentilla fulgens on Tuba Uterina in Ovariectomized Rats(Soc Chilena Anatomia, 2016) Acar, Zuat; Deger, U.; Gorkem, U.; Togrul, Cihan; Deveci, E.; Kaya, S.; Ekinci, A.A total of 32 Wistar rats were divided into four equal groups: (I) sham, (II) ischemia, (III) reperfusion and (IV) Potentilla fulgens. In groups I and II, ovary torsion was not performed and no drug was administered. In group III, 1 h of ischemia and 2 h of reperfusion were performed and no drug was given. Group IV received 400 mg/kg/day Potentilla fulgens intraperitoneally 5 days before Ischemia-reperfusion. All the parameters were observed to be significantly decreased (P<0.05) in all the experimental groups compared to the control group. In the sections of the ischemia-reperfusion group, degeneration of epithelium, dilation of blood vessels were observed. Potentilla fulgens administration reduced the morphological changes by induced I/R; in particular, infiltration, hemorrhage and vascular dilatation were decreased. Potentilla fulgens application during torsion, it plays an important role in maintaining the epithelial structure with E-cadherin expression. We suggest that PECAM-1(CD31) are a regulator of the microvascular response of the tubal mucosa.Öğe Evaluation of Adults with Acute Viral Hepatitis A and Review of the Literature(Soc Editrice Univ, 2013) Tekin, R.; Yolbas, I.; Dal, T.; Demirpence, O.; Kaya, S.; Bozkurt, F.; Deveci, O.Aim. In developing countries HAV infection is very common in the first years of life and it is often asymptomatic. However especially in regions of intermediate endemicity, exposure to the virus may delay and outbreaks of hepatitis A may be encountered in adults. The aim of this study is to evaluate the clinical and laboratory findings and risk factors of adults with acute viral hepatitis A. Materials and Methods. In present study we evaluated 203 patient with acute viral hepatitis A, who were admitted to four different hospitals of three cities of Turkey between January 2000-December 2011, retrospectively. The diagnosis of acute viral hepatitis A was performed by laboratory findings and clinically. Results. In a total of 203 patients, 120 (59.1%) patients were male and 83 (40.9%) were female. Mean age of cases with acute viral hepatitis A was 24.7 + 11.8 years (ranged 15 to 82 years old). Acute viral hepatitis A were seen in patient who were 15-20 years and 21-30 years old, commonly. Jaundice (74%), fatigue (68%), nausea-vomiting (56%) and dark urine (48%) were the most common symptoms in cases. Prolonged cholestasis (6.8%) was the most common atypical manifestation. Prolonged jaundice was more frequent in the cases with positive HBsAg (P<0.001). Conclusions. Acute viral hepatitis A can cause atypical presentations such as prolonged cholestasis, acute kidney injury and fulminant hepatitis. Some precautions such as routine vaccination program, improvement of hygiene conditions and informing people about it, should be taken for reducing of acute viral hepatitis A infection incidence.Öğe Incisor trauma in a Turkish preschool population: Prevalence and socio-economic risk factors(F D I World Dental Press Ltd, 2011) Tumen, E. C.; Adiguzel, O.; Kaya, S.; Uysal, E.; Yavuz, I.; Ozdemir, E.; Atakul, F.Objective: This study aimed to assess the prevalence of traumatic injuries of the primary incisors in preschool children from 2 to 5 years old in South-Eastern Anatolia, Turkey. Additionally, the relationship between traumatic dental injuries, parents' education level, family income, size of incisal overjet and the presence of anterior open bite were examined. Basic research design: A cross-sectional survey Clinical settings: Data were collected through oral examinations and structured interviews, and included socio-economic indicators. Participants: A total of 727 children of both genders were included in the study. 122 of these children were aged 2; 183 aged 3; 178 aged 4 and 186 aged 5. Results: The prevalence of dental injuries was 8.0% (n=58). The highest frequency of trauma in the primary teeth was observed at the age of 4. Boys experienced more dental injuries than girls, 12.2% and 4.0%, respectively. The most common crown fracture was in enamel only (57%) followed by crown fracture of enamel and dentin (19%). Conclusion: The prevalence of dental injuries in Turkish preschool children was very low. The children with incisal overjet greater than 5mm and anterior open bite experienced more dental injuries in primary teeth than their counterparts with normal occlusion. Socio-economic indicators were not statistically significantly associated with the occurrence of traumatic dental injuries.Öğe Liver involvement in patients with brucellosis: results of the Marmara study(Springer, 2014) Ozturk-Engin, D.; Erdem, H.; Gencer, S.; Kaya, S.; Baran, A. I.; Batirel, A.; Tekin, R.Brucellosis is a zoonotic disease that primarily affects the reticuloendothelial system. But, the extent of liver damage in due course of the disease is unclear. This study included 325 brucellosis patients with significant hepatobiliary involvement identified with microbiological analyses from 30 centers between 2000 and 2013. The patients with a parts per thousand yen5 times of the upper limit of normal for aminotransferases, total bilirubin level a parts per thousand yen2 mg/dl or local liver lesions were enrolled. Clinical hepatitis was detected in 284 patients (87.3 %) and cholestasis was detected in 215 (66.1 %) patients. Fatigue (91 %), fever (86 %), sweating (83 %), arthralgia (79 %), and lack of appetite (79 %) were the major symptoms. Laboratory tests showed anemia in 169 (52 %), thrombocytopenia in 117 (36 %), leukopenia in 81 (25 %), pancytopenia in 42 (13 %), and leukocytosis in 20 (6 %) patients. The most commonly used antibiotic combinations were doxycycline plus an aminoglycoside (n = 73), doxycycline plus rifampicin (n = 71), doxycycline plus rifampicin and an aminoglycoside (n = 27). The duration of ALT normalization differed significantly in three treatment groups (p < 0.001). The use of doxycycline and an aminoglycoside in clinical hepatitis showed better results compared to doxycycline and rifampicin or rifampicin, aminoglycoside, doxycycline regimens (p < 0.05). However, the length of hospital stay did not differ significantly between these three combinations (p > 0.05). During the follow-up, treatment failure occurred in four patients (1 %) and relapse was seen in three patients (0.9 %). Mortality was not observed. Hepatobiliary involvement in brucellosis has a benign course with suitable antibiotics and the use of doxycycline and an aminoglycoside regimen seems a better strategy in select patients.Öğe A novel peptide-specific monoclonal antibody with a potential use for immunotherapy recognizes AMHR2 expressed by ovarian cancer cells(Elsevier Sci Ltd, 2016) Sakalar, C.; Aksu, H.; Turan, A.; Kaya, S.; Mustafa, C.; Busra, K.; Sedat, S.[Abstract Not Available]