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Öğe Assessment of anticoagulant medication use and stroke risk in patients with valvular atrial fibrillation; results from atrial fibrillation in Turkey: Epidemiologic Registry (AFTER)(Oxford Univ Press, 2013) Kaya, H.; Ertas, F.; Gedik, S.; Eren, N. K.; Yuksel, M.; Koroglu, B.; Kose, N.[Abstract Not Available]Öğe Circadian variation of blood Pressure is impaired in normotensive pregnant women with gestational diabetes mellitus(Oxford Univ Press, 2012) Soydinc, E.; Davutoglu, V.; Sak, E.; Evsen, S.; Kaya, H.; Ercan, S.; Sari, I.[Abstract Not Available]Öğe Comparing the results of PET/CT, CT and Tc-99m Aerosol scintigraphy in malign pleural mesothelioma and asbestozis(Springer, 2011) Aguloglu, N.; Kaya, H.; Komek, H.; Kaplan, M.; Bogatekin, G.[Abstract Not Available]Öğe Comparision computerized tomography and brain SPECT in patients with acute ischemic stroke diagnosis(Springer, 2009) Kaya, H.; Altunci, G. Kaya; Tamam, Y.; Karahan, C. Can[Abstract Not Available]Öğe A comparison of oral glucose and GIK infusion with F18 FDG PET study in evaluation of myocardial viability(Springer, 2010) Kaya, H.; Balci, T. Ansal; Komek, H.; Bellur, B. Kizilkan; Bellur, G.[Abstract Not Available]Öğe Diagnostic value of IGF-1 and IGFBP-3 in prostate cancer and benign prostate hyperplasia(Springer, 2008) Kaya, H.; Altunci, G. Kaya; Ar, S.; Dag, Y.; Gedik, A.[Abstract Not Available]Öğe Effects of treatment regimens on survival in patients with malignant pleural mesothelioma(Verduci Publisher, 2013) Abakay, A.; Abakay, O.; Tanrikulu, A. C.; Sezgi, C.; Sen, H.; Kaya, H.; Kucukoner, M.BACKGROUND AND OBJECTIVE: In this study, we aimed to investigate the factors affecting the survival of patients with malignant pleural mesothelioma (MPM) according to their treatment regimens, including best supportive care (BSC), chemotherapy, surgical group and multimodality (MM) therapy. PATIENTS: A retrospective analysis was performed on clinical data and treatment outcomes of 400 patients registered in our hospital with MPM between January 1989 and April 2010. RESULTS: Mean age (p < 0.001), presence of asbestos exposure (p = 0.0014), presence of smoking history (p < 0.001), Karnofsky performance status (p < 0.001), histological subtype (p = 0.034) and stage (p < 0.001) variables were found to be significantly different among the four treatment regimens. Mean survival time of all patients was 12.32 months. Mean survival time 10.5 months for the BSC group, 15.7 for the surgical group, 16.02 for the chemotherapy group, and 26.55 for the MM group. There were significant differences in mean survival time among the four treatment regimens. In addition, a significant difference was found in survival time between the two chemotherapy groups (p = 0.032). Mean survival time for cisplatin + gemcitabine was found to be 14.49 months and for cisplatin + pemetrexed, 18.34 months. CONCLUSIONS: The MM group had better survival rates than the other groups. The new chemotherapy combination, cisplatin + pemetrexed, can be helpful in improving survival time.Öğe Evaluation of primary and recurrent colorectal cancer patients with Tc99m IMMU-4(Fab' fragment) radioimmunoscintigraphy(Springer, 2008) Ar, S.; Kaya, H.; Girgin, S.; Altunci, G. Kaya; Gedik, E.[Abstract Not Available]Öğe Evaluation of Rivastigmine Therapy with Tc99m HMPAO Brain Perfusion SPECT and MMSE Scores in Alzheimer's Disease(Springer, 2005) Cerci, S. S.; Kaya, H.; Yildiz, M.; Tamam, Y.; Arslan, S.[Abstract Not Available]Öğe Family functioning and its clinical correlates in overweight and obese patients(Editrice Kurtis S R L, 2011) Bez, Y.; Ari, M.; Gokce, C.; Celik, M.; Kaya, H.AIM: Our aim is to evaluate the differences in family functioning and anxiety between normal, overweight, and obese subjects. METHOD: Overweight and obese patients were selected from the outpatient clinic of internal medicine department of a university hospital. Patients were classified into three groups as normal weight (N=82), overweight (N=33) and obese (N=50) patients. The normal weight group included healthy subjects. The individuals were examined by the same psychiatrist (MA). Beck Anxiety Inventory and Family Assessment Device were applied to all groups. RESULTS: When compared to normal weight patients, obese and overweight patients had significantly higher anxiety scores and higher scores in general functions, problem solving, communication, roles, affective responsiveness, and behavior control dimensions which reflect increased dysfunctions in their families. The total level of dysfunction that patients experience was predicted by alcohol dependence in the family during childhood period, any medical disorder in the current family, anxiety level and body mass index. CONCLUSION: When treating them clinicians should keep in mind that families of obese and overweight patients may have higher levels of dysfunctions. (Eating Weight Disord. 16: e257-e262, 2011). (C)2011, Editrice KurtisÖğe Gamma probe-guided surgery for completition thyroidectomy(Springer, 2009) Kaya, H.; Karahan, C. Can; Altindag, S.; Gedik, E.; Cetinkaya, O.[Abstract Not Available]Öğe Implantable cardioverter defibrillator pocket infection caused by Klebsiella pneumonia(Makerere Univ, Fac Med, 2012) Ertas, F.; Acet, H.; Kaya, H.; Kayan, F.; Soydinc, S.Like any other foreign bodies, implanted cardiac devices can become infected. Staphylococcus aureus and coagulase-negative Staphilococci are the most common causes of infections of pacemaker and defibrillator systems. In this case an implantable cardioverter defibrillator pocket infection caused by an extremely rare microorganism, Klebsiella pneumonia, is presented.Öğe Increased echocardiographic epicardial fat thickness is related to impaired diurnal blood pressure profiles(Oxford Univ Press, 2013) Ertas, F.; Kaya, H.; Acet, H.; Cil, H.; Akyuz, A.; Islamoglu, Y.; Tekbas, E.[Abstract Not Available]Öğe An Index Proposal for the Evaluation of Myocardial Viability(Springer, 2011) Kaya, H.; Balci, T. A.; Komek, H.; Bellur, B. Kizilkan[Abstract Not Available]Öğe Lower serum free tri-iodothyronine levels are associated with presence and severity of coronary artery disease in the euthyroid patients(Oxford Univ Press, 2012) Ertas, F.; Kaya, H.; Cil, H.; Akil, M. A.; Atilgan, Z. A.; Islamoglu, Y.; Oylumlu, M.[Abstract Not Available]Öğe Noncompaction of the left ventricular myocardium diagnosed during ventriculography(Verduci Publisher, 2012) Elbey, M. A.; Atilgan, Z.; Kaya, H.; Ertas, F.[Abstract Not Available]Öğe The predictors of poor outcomes in patients with femoral artery injuries(Verduci Publisher, 2013) Yavuz, C.; Demirtas, S.; Caliskan, A.; Ertas, F.; Kaya, H.; Aydin, M.; Benli, E. D.PURPOSE: This study investigated the predictors of poor outcomes, including limb loss and death, in patients with femoral artery injuries. PATIENTS AND METHODS: The study included 158 patients aged 2-82 (mean age 28.4 +/- 16.5) with femoral arterial injury (common, deep, and superficial femoral artery) that were treated surgically between 2000 and 2010. Isolated venous injuries were excluded. Demographic and clinical data of the patients, including age, gender, admission time, pulse rate and blood pressure, hematocrit value, reason of injury, associated injury, and Mangled Extremity Severity Score (MESS) were recorded. RESULTS: Of the 158 patients, the death and amputation rates were 5.7% (9) and 5.1% (8), respectively. In logistic regression analysis, four variables (pulse rate, MESS, hematocrit, and bone trauma) were found to be independent predictors for poor outcomes. The Odd's ratios and confidence interval values of these variables were as follows: 7.24 (1.94-26.92), 21.75 (5.4187.48), 5.93 (3.04-11.54) and 7.46 (2.09-9.56), respectively. CONCLUSIONS: The MESS value, presence of bone fracture, hematocrit, and pulse rate on admission are predictive risk factors for poor outcomes in patients with femoral artery injury. Therefore, in these patients, prompt intervention by experienced surgeons is crucial for limb salvage and decreased mortality.Öğe Prognostic factors influencing survival in 35 patients with malignant peritoneal mesothelioma(Aepress Sro, 2014) Kaya, H.; Sezgi, C.; Tanrikulu, A. C.; Taylan, M.; Abakay, O.; Sen, H. S.; Abakay, A.Malignant mesothelioma is a rare but highly lethal form of cancer that affects the serosal membranes. Malignant peritoneal mesothelioma (MPM) is the second most common form of malignant mesothelioma (pleural mesothelioma is the most common). The aim of this study was to evaluate prognostic factors influencing the survival of patients with MPM. A retrospective analysis was performed on 35 patients who were admitted to our hospital between March 2005 and July 2013. The patients' demographic and clinical data, laboratory results, radiological signs, Eastern Cooperative Oncology Group (ECOG) performance status (PS), and treatment outcomes were evaluated. The mean age of the 35 patients was 59.0 +/- 14.4 years, the mean survival time was 16.2 +/- 12.9 months, and the majority of the histopathological types of MPM were epithelial (68.6%). 82.9% of the patients had been exposed to asbestos, and the mean duration of exposure was 28.3 +/- 14.5 years. The most frequent symptoms were abdominal distention/pain, weight loss, dyspnea, and chest pain. The mean interval between the onset of symptoms and the diagnosis was 4.6 +/- 3.3 months. Platinum-based combination chemotherapy in combination with supportive care was used in the treatment of 68.6% of the patients, while supportive treatment alone was used in the others. Our results revealed that patients who were >60 years old (p=0.019), who were exposed to asbestos >20 years (p=0.033), who had an ECOG PS of 3 (p=0.000) were more likely to have a poor MPM prognosis. In conclusion, increased age, duration of environmental asbestos exposure and ECOG PS are important factors that influence the prognosis of MPM patients.Öğe Radioimmun therapy with (90)Y-Ibritumomab tiuxetan in patients with non-hodgkin's lymphoma(Springer, 2009) Kaya, H.; Ayyildiz, O.; Altunci, G. Kaya; Bellur, B. Kizilkan; Isikdogan, A.[Abstract Not Available]Öğe Relationship between endothelial dysfunction and prosthetic heart valve thrombosis: a preliminary investigation(Verduci Publisher, 2013) Kaya, H.; Ozkan, M.; Yildiz, M.AIM: The etiopathogenesis of prosthetic heart valve thrombosis (PHVT) is multifactorial. Since the relationship between PHVT and endothelial function is never studied, we aimed to analyze the role of endothelial function in patients with PHVT. PATIENTS AND METHODS: Twenty-two patients with PHVT (14 female, 31.8% with atrial fibrillation, mean age 46.0 +/- 12.2) and 22 controls with prosthetic heart valves (17 female, 36.4% with atrial fibrillation, mean age 45.7 +/- 11.5) were prospectively evaluated. Two groups had similar demographic and echocardiographic characteristics. Endothelial function was evaluated in all patients by the non-invasive measurement of flow mediated dilatation (FMD) of brachial artery. High-resolution ultrasound was used to measure brachial artery diameter at rest, during reactive hyperemia (endothelium-dependent, FMD), and following sublingual administration of nitroglycerin (endothelium-independent, nitroglycerin-mediated vasodilatation, NMD). RESULTS: Functional capacity at presentation determined as mean NYHA functional capacity class was worse in patients with PHVT than in control group (2.1 +/- 0.6 vs. 1.3 +/- 0.6; p < 0.0001). FMD was significantly reduced in patients with PHVT compared with control group (4.01 +/- 1.52 vs. 8.48 +/- 3.37; p < 0.0001). NMD did not differ between two groups (11.77 +/- 2.30 vs. 13.38 +/- 3.50; p = 0.08). FMD level of < 5.65 predicted prosthetic valve thrombosis with an 82% sensitivity and 77% specificity (area under the curve = 0.888, p < 0.0001). CONCLUSIONS: This study demonstrated the endothelial dysfunction in patients with PHVT compared with well-matched control group. In this study, we found that patients with PHVT have endothelial dysfunction which might contribute to the development of thrombosis.
