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Öğe Acupuncture stimulation causes earlier increase in the size and blood flow of corpus luteum and progesterone levels in dairy cows(Wiley-Blackwell, 2015) Kucukaslan, I.; Aslan, S.; Ay, S. S.; Kaya, D.; Findik, M.; Kacar, C.; Wollgarten, B.[Abstract Not Available]Öğe Beneficial effects of Beta-carotene injections prior to treatment with PGF2? on the fertility of postpartum dairy cows(Ecole Nationale Veterinaire Toulouse, 2012) Ay, S. S.; Kaya, D.; Kucukaslan, I.; Agaoglu, A. R.; Emre, B.; Handler, J.; Findik, M.This study examined the effects of Beta-carotene (beta C) injections before estrus synchronization with PGF(2)alpha on fertility parameters in cows. A total of 124 postpartum (pp) cows were used. In GI (n=25), beta C (Carofertin (R), 0.4 mg/kgBW, i.m.) was injected on d 15 and 45 pp. In GII (n=25), beta C was administered on d 15 pp. In GIII (n=25), beta C was administered on d 45 pp. In GIV (n=25), beta C was injected on d 35 and 45 pp. GV (n=24) was set aside as a control group. All animals received PGF(2)alpha (Iliren (R), 0.0015 mg/kgBW, i.m.) on d 50 and 61 pp. Blood samples were collected on d 15,48 and three days after each beta C injection. The overall pregnancy rate was determined to be higher in GI (100%) and GIV (88.0%) than GV (70.8%) (P<0.01). The number of services per conception was the lowest in GI (1.4) and GII (1.4), while days of first service were lower in GIII (90.3 d) and GIV (90.8 d) (P<0.05). The insemination index was found to be lowest in GI (1.4). These results suggest that two administrations of beta C in the early and late pp period before administering PGF(2)alpha can improve fertility. It was concluded that when serum beta C concentrations remain high for a long time (30d) as a results of beta C injections, fertility can be improved.Öğe Clinical and endocrinological effects of two different treatments for the induction of abortion in bitches(Wiley-Blackwell, 2011) Kaya, D.; Kucukaslan, I.; Agaoglu, A.; Ay, S.; Schafer-Somi, S.; Emre, B.; Bal, Y.[Abstract Not Available]Öğe The effect of acupuncture application during diestrus periods on the size and blood flow of corpus luteum and hormonal parameters in dairy cows(Wiley-Blackwell, 2014) Kucukaslan, I.; Ay, S. S.; Kaya, D.; Findik, M.; Aslan, S.[Abstract Not Available]Öğe The effectiveness of combined preventive treatment with Ceftiofur, Oxytocin and PGF2? on fertility parameters in cows(Ecole Nationale Veterinaire Toulouse, 2012) Kaya, D.; Ay, S. S.; Kucukaslan, I.; Beceriklisoy, H. B.; Agaoglu, A. R.; Findik, M.; Ozyurtlu, N.The present study is aimed at evaluating the effectiveness of combined preventive treatment with Ceftiofur Hydrochloride (CHR), Oxytocin (OXT) and PGF(2 alpha) on fertility parameters and puerperal disorder rates in postpartum (pp) dairy cows. A total of 191 Holstein-Friesian cows were divided into four groups. The cows in group I (GI; n=37) and II (GII; n=69) were treated on a daily basis with CHR and OXT for five and three days pp, respectively. Group III (GIII; n=52) was designed as the PGF(2 alpha) group, and group IV (GIV; n=33) served as a control group. The animals in GI, GII, and Gill were given a PGF(2 alpha) analogue on days 15 and 26 pp. Each group was further divided into subgroups of normal parturition (np) and dystocia (d) when the study results were evaluated. It was found that the first service pregnancy rates for the subgroup of dystocia were significantly higher (P<0.05 and P<0.01) in subgroup GII (76.9%) than in GI (30.0%) and GIV (37.5%). Furthermore, the median time to first service and the median time to pregnancy were longer for cows in subgroup GIVd as compared with subgroups GId, GIId, and GIIId (P<0.001; P<0.01). Group II was found to have the lowest endometritis rates after treatment of subgroups-d and -np. No statistically significant difference was found between the groups with regard to cystic ovary rates after treatment (P>0.05). As the treatment with CHR-OXT combined with PGF(2 alpha) on days 15 and 26 was associated to improved uterine involution patterns and reproductive performance, our results suggest that administration of this preventive treatment would be useful, especially for cases of dystocia.Öğe Effectiveness of Thuja occidentalis and Urtica urens in pseudopregnant bitches(B W K Publishing Solutions & Verlag, 2008) Beceriklisoy, H. B.; Ozyurtlu, N.; Kaya, D.; Handler, J.; Aslan, S.The aim of this study was to investigate the effectiveness of Thuja occidentalis and Urtica urens in pseudopregnant bitches. Clinically pseudopregnant bitches (n=38) were assigned per random to groups as follows: Group I: Thuja occidentalis D30 (8 globules, 3 times a day, per os, n=15); Group II: Urtica urens D6 (8 globules, 3 times a day, per os, n=15); Group III: naloxone (control group, 0.01 mg/kg, twice daily, s.c., n=8). Treatments were continued until clinical signs resolved. Animals were classified as no, mild, moderate, and severe (score -, +, ++, and +++) according to the clinical signs of mammary glands and behavioural signs during the study. Bitches were examined at 3-5 days intervals by means of adspection and palpation until clinical signs resolved. Successful recovery rates (100 %) were found in Group I and II. Application of naloxone was found to be successful in only 3 of 8 bitches (37.5 %). Mean duration of treatments in Group I, II and III was 11.6 +/- 4.6 (min-max: 3-18) days, 13.5 +/- 3.7 (min-max: 6-19) days and 14.3 +/- 5.9 (min-max: 10-21) days, respectively. During treatment with Thuja occidentalis D30 and Urtica urens D6, the percentages of bitches with behavioural problems significantly decreased within 3-5 days from 33.3 % to 6.7 % (p=0.033) and from 66.7 % to 33.3 % (p=0.050), respectively. All bitches treated with Thuja occidentalis D30 or Urtica urens D6 showed normal behaviour within 10 days after onset of treatments but 2 bitches in the naloxone group kept showing behavioural signs until Days 15-20 of treatment. Concerning mammary gland scores, treatments yielded significantly higher success rates in Group I and Group II (100 in both groups) compared to the success rate observed in Group III (37.5 %; p=0.012). No side effects were observed during the study. In conclusion, the homeopathic agents Thuja occidentalis D30 and Urtica urens D6 proved to be effective and safe in pseudopregnant bitches.Öğe The effects of aglepristone alone and in combination with cloprostenol on hormonal values during termination of mid-term pregnancy in bitches(Elsevier Science Bv, 2014) Kaya, D.; Kucukaslan, I.; Agaoglu, A. R.; Ay, S. S.; Schaefer-Somi, S.; Emre, B.; Bal, Y.This study was designed to assess endocrine changes associated with termination of midterm pregnancy after use of two different protocols. For this purpose we compared the effects of aglepristone (AGL) alone and in combination with cloprostenol (CLO) on serum concentrations of progesterone (P-4), estradiol (E-2) and relaxin (RLN) measured at shortterm intervals during the abortion period in bitches. Fourteen pregnant bitches between day 25 and 32 of gestation were used in the study. In the AGL group (n = 7), aglepristone was administered solely (10 mg/kg body weight (BW), subcutaneously, once daily on two consecutive days) whereas in the AGL-CLO group (n = 7), aglepristone (dosage as in AGL group) and cloprostenol (1 mu g/kg BW, subcutaneously, same with aglepristone) were combined. All pregnancies were successfully terminated 5.2 1.6 days after initiation of treatments, which was significant in both groups (P> 0.05). At the time of the start of abortion (SA) and the end of abortion (EA), the mean P4 concentrations were 26.6 7.3 and 12.0 6.4 ng/ml in AGL group, and 2.7 0.7 and 0.9 0.1 ng/ml, in AGL-CLO group, respectively (P< 0.01). Serum E-2 concentrations were significantly higher (P< 0.05) in AGL group at 42, 48, 54 hand SA after initiation of treatment. In the AGL-CLO group, serum RLN concentrations did not significantly change from the initiation of treatment to EA (P> 0.05). However, markedly higher RLN concentrations (P< 0.05) were observed in the AGL group at 48 h (1.5 0.7 ng/ml) and at SA (1.6 0.5 ng/ml). The results of the present study indicate that changes in the hormonal concentrations affect the mechanism of abortion in different ways. Further in depth studies investigating changes in the expression of hormone receptors inside the ovary, endometrium and placenta might be helpful to our understanding of the endocrinological differences observed in this study. (C) 2014 Elsevier B.V. All rights reserved.Öğe Evaluation of endometrial echotexture and cervical cytology in cows during and after treatment of endometritis(Georg Thieme Verlag Kg, 2014) Kucukaslan, I.; Kaya, D.; Emre, B.; Bollwein, H.; Ozyurtlu, N.; Mulazimoglu, S. B.; Aslan, S.Objective: The aim of this study was to evaluate changes in the endometrium by using echotexture parameters during and after treatment of endometritis with intrauterine administration of an intrauterine antiseptic solution (Lotagen (R), 3% metacresolsulphonic acid and formaldehyde) in cows which became pregnant after treatment. Material and methods: According to the severity of endometritis 21 cows were divided into three groups: El (slight, n = 7), E2 (moderate, n = 8), E3 (severe, n = 6). The control group (C, n = 11) consisted of cows without endometritis that did not receive an intrauterine medication. A software (Bs200 Pro (R)) was used to evaluate echotexture parameters Contrast (CON), Gradient (GR), Homogeneity (HUM), Mean Gray Level (MGL) of images taken during the examinations at hours (h) 0, 1 and 6 and days (d) 2, 3, 5 and 10. Results: At 0 h, GR was significantly lower in group E2 than in groups El and C (p < 0.05). There was an increase in GR values between 0 h and 10 d in group E2 and E3, but a decrease during the same time interval in group C (p < 0.05). In contrast, CON values of group E2 were lower (p < 0.05) at 0 h compared to other timepoints of examination and lower than in group C. HOM values were lower (p < 0.05) in groups El, E2 and E3 than in group Con d 5 and d 10. HUM values were higher at 1 h compared to 6 h, d 2 and d 10 in group E3 (p < 0.05). By contrast to GR values, HUM values were higher in group C at 6 h and d 10 than they were in group E3. MGL values of group E2 were higher (p < 0.05) than in group C until d 10 and higher (p < 0.05) in group E3 than in group C at 6 h after treatment. In group E2 an increase of MGL values until d 2 was followed by a decrease (p < 0.05). Conclusion: Echotexture parameters determined by the evaluation of sonographic B-mode images reflect changes in the endometrium and could be used for the evaluation of the recovery period after treatment of endometritis.Öğe Serum IL-27, IL-23 and IL-35 Levels in Neuromyelitis Optica Spectrum Disorders with Aquaporin-4 and Multiple Sclerosis(Sage Publications Ltd, 2018) Idiman, Egemen; Kaya, D.; Hasankoyoglu, O.; Keskin, A. O.; Tasdemir, N.; Altun, Z.[Abstract Not Available]Öğe Use of Echo-texture Parameters for the Determination of Different Degree Endometritis in Cows and Evaluation of the Recovery Period after Treatment(Wiley-Blackwell Publishing, Inc, 2009) Kucukaslan, I.; Kaya, D.; Emre, B.; Ozyurtlu, N.; Aslan, S.[Abstract Not Available]
