Yazar "Karapinar, Hekim" seçeneğine göre listele

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    Evaluation of the long-term effect of percutaneous balloon valvuloplasty on the right ventricular function using tissue Doppler imaging in patients with mitral stenosis
    (Turkish Soc Cardiology, 2014) Kaya, Zekeriya; Karapinar, Hekim; Kaya, Hasan; Esen, Ozlem Batukan; Akcakoyun, Mustafa; Acar, Goksel; Esen, Ali Metin
    Objectives: We investigated the long-term effects of percutaneous mitral balloon valvuloplasty (PMBV) on the right ventricular function using tissue Doppler imaging. Study design: Twenty-seven patients who underwent successful PMBVs were enrolled in the study. Echocardiographic examination, including color tissue Doppler imaging, was done from the lateral tricuspid ring 24 hours before the intervention. The echocardiographic examination was repeated 24 hours, and 6 months after the intervention. Results: At 24 hours after the intervention, significant increases were observed in S, and A' wave velocities (9.52 +/- 1.85 cm/s vs. 10.92 +/- 1.20 cm/s, p= 0.012; -10.44 +/- 2.64 cm/s vs. -11.73 +/- 2.05 cm/s, p= 0.029, respectively). E' wave velocity and E'/A' ratio did not change significantly (p> 0.05 for both). At 6. postprocedural month, S wave velocity was similar to the value in the early postoperative period, but higher than the baseline level (9.52 +/- 1.85 cm/s vs. 10.69 +/- 1.72 cm/s, p= 0.023). However, A' wave velocity in the late postoperative period was decreased compared to the early period and was not significantly different from the baseline level (-10.44 +/- 2.64 cm/s vs. -10.74+/- 2.63 cm/s, p> 0.05). The increase in E' wave velocity in the late period when compared to the baseline level was found to be statistically significant (7.85 +/- 1.54 cm/s vs. -9.21 +/- 1.81 cm/s, p= 0.046). Conclusion: Right ventricular systolic function improved in the early period, and this improvement was seen to continue in the late post-PMBV period.. Diastolic function did not improve in the early period, but did improve in the late period. Right atrium systolic function improved in the early period; however, in the late period, levels returned to baseline levels.
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    Öğe
    A multicenter study on experience of 13 tertiary hospitals in Turkey in patients with infective endocarditis
    (Turkish Soc Cardiology, 2013) Elbey, Mehmet Ali; Akdag, Serkan; Kalkan, Mehmet Emin; Kaya, Mehmet G.; Sayin, M. Rasit; Karapinar, Hekim; Bulur, Serkan
    Objective: The aim of this retrospective multicenter study was to investigate the clinical manifestations, microbiological profile, echocardiographic findings and management strategies of infective endocarditis (IE) in Turkey. Methods: The study population consisted of 248 Turkish patients with IE treated at 13 major hospitals in Turkey from 2005 to 2012 retrospectively. All hospitals are tertiary referral centers, which receive patients from surrounding hospitals. Data were collected from the medical files of all patients hospitalized with IE diagnosed according to modified Duke Criteria. Results: One hundred thirty seven of the patients were males. Native valves were involved in 158 patients while in 75 participants there was prosthetic valve endocarditis. Vegetations were detected in 223 patients (89%) and 52 patients had multiple vegetations. Mitral valve was the most common site of vegetation (43%). The most common valvular pathology was mitral regurgitation. The most common predisposing factor was rheumatic valvular disease (28%). Positive culture rate was 65%. Staphylococci were the most frequent causative microorganisms isolated (29%) followed by enterococci (11%). In-hospital mortality rate was 33%. Conclusions: Compared to IE in developed countries younger age, higher prevalence of rheumatic heart disease, more frequent enterococci infection and higher rates of culture negativity were other important aspects of IE epidemiology in Turkey.
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    Öğe
    Neutrophil to Lymphocyte Ratio is Predictor of Atrial Fibrillation Recurrence After Cardioversion With Amiodarone
    (Sage Publications Inc, 2015) Karavelioglu, Yusuf; Karapinar, Hekim; Yuksel, Murat; Memic, Kadriye; Sarak, Taner; Kurt, Recep; Yilmaz, Ahmet
    Background: In this study, our aim is to examine the role of the neutrophil to lymphocyte ratio (NLR) in the predictions of recurrence under long-term follow-up in patients whose sinus rhythms (SRs) were restored with amiodarone in acute atrial fibrillation (AF). Methods: Retrospectively, patients with acute AF, which successfully converted to the SR with amiodarone treatment, were recruited into the study. Patients experiencing the first AF attack were enrolled to the study and followed up for 5 years (median 23 months, 25-75 percentiles 12-24 months). Neutrophil to lymphocyte ratio was computed as absolute neutrophil count divided by lymphocyte count. Results: A total of 218 patients were recruited into the study and followed up for 21.6 13.9 months; 87 (40%) patients had 1 recurrent AF attack within this period. The follow-up of 131 (60%) patients resulted in persisted SR without any other AF attack. Groups were similar in terms of age and gender. Left atrium (LA) diameter and NLR were increased, and platelet count and lymphocyte count were decreased in patients with AF recurrence in univariate analysis (P < .05 for all). Only LA diameter (for per mm, 1.077 [1.021-1.136], P = .006) and NLR (1.584 [1.197-2.095], P = .001) were independent predictors of AF recurrence in the multivariate analysis. Conclusion: Increased NLR is a marker of increased inflammation and may serve as simple, cheap, and readily available predictors of recurrence in the long-term follow-up of patients admitted with acute AF and successfully converted to SR with amiodarone.