Yazar "Karakoc, Mehmet" seçeneğine göre listele
Listeleniyor 1 - 12 / 12
Sayfa Başına Sonuç
Sıralama seçenekleri
Öğe Assessment of sexual function and quality of life in patients with lower limb amputations(Ios Press, 2019) Em, Serda; Karakoc, Mehmet; Sariyildiz, Mustafa Akif; Bozkurt, Mehtap; Aydin, Abdulkadir; Cevik, Remzi; Nas, KemalBACKGROUND: Diseases causing disabilities lead to sexual dysfunction. However, studies that evaluate sexual functions in patients with traumatic lower limb amputations (LLA) are limited and controversial. OBJECTIVE: The objective is to evaluate sexual functions in male patients with LLA and to identify factors that might contribute to sexual dysfunction. The hypothesis is that male patients with LLA would experience worse sexual and emotional functioning and consequently emotional impairment that consequently influenced the sexual function. METHODS: Sixty men with traumatic LLA and 60 healthy men were assessed according to the International Index of Erectile Function (IIEF) scoring system. Emotional state was assessed by the Beck Depression Inventory (BDI) and Beck Anxiety Inventory (BAI), and the quality of life by the Short Form-36 Health Survey (SF-36). RESULTS: Patients had significantly lower scores in the IIEF total score and subscores in comparison with the controls. Intercourse satisfaction scores were significantly higher (p < 0.05) in patients with trans-tibial amputation than in those with trans-femoral amputation. BDI and BAI scores negatively correlated with erectile function, sexual desire, intercourse satisfaction, overall satisfaction and total IIEF scores. The mental and physical scores of SF-36 significantly correlated with some of the sub scores and IIEF total scores. The power of statistical analysis for study population was 100% according to the given effect size (alpha = 0.01). CONCLUSION: The present study suggests that the LLA leads to impairments in the sexual function and quality of life in male patients. Also, sexual dysfunction in patients is strongly associated with emotional state, pain, level of amputation and quality of life.Öğe Association between Serum Follistatin-Like Protein 1 Levels and Disease Activity in Behçet's Disease(Georg Thieme Verlag Kg, 2023) Demir, Mesut; Batmaz, Ibrahim; Sariyildiz, Mustafa Akif; Ekinci, Aysun; Akar, Zeynel Abidin; Batmaz, Oznur; Karakoc, MehmetIntroduction This study sought to determine the serum levels of follistatin-like protein 1 (FSTL-1), a glycoprotein of mesenchymal origin shown to be involved in the pathogenesis of many inflammatory diseases, for example Behcet's disease (BD), and to investigate its association with disease activity.Material and Methods The study included 45 patients followed for newly diagnosed Behcet's disease who met the 1990 International Study Group criteria for BD and a control group of 36 healthy volunteers who were age- and gender-matched. Peripheral blood samples were collected from the patients and control groups. Serum FSTL-1 levels were measured using an enzyme-linked immunosorbent assay. The disease activity was assessed using the Behcet's Disease Current Activity Form (BDCAF).Results A comparison of serum FSTL-1 levels in the patient and control groups found significantly higher levels of FSTL-1 in the patient group. Serum FSTL-1 levels were significantly higher in female patients compared with male patients. Female patients exhibited significantly higher BDCAF scores compared with male patients (p=0.008). Erythrocyte sedimentation rate and serum FSTL-1 levels were positively correlated.Conclusion Serum FSTL-1 levels may play a role in the aetiopathogenesis of BD and can also be a useful biomarker for determining disease activity.Öğe Effects of the use of conventional versus computer-aided design/computer-aided manufacturing sockets on clinical characteristics and quality of life of transfemoral amputees(Derman Medical Publ, 2019) Aydin, Abdulkadir; Atic, Ramazan; Aydin, Zekiye Sevinc; Alemdar, Celil; Karakoc, Mehmet; Nas, Kemal; Em, SerdaAim: Amputee mobilisation requires prosthetic device use regardless of the amputation level and type. The socket is the most important part of the prosthesis and is manufactured by conventional methods worldwide. Recently, computer-aided design/computer-aided manufacturing systems have been frequently used in Europe and the United States for socket design. Use of the computer-aided design/computer-aided manufacturing method for socket production is increasing day by day. Are the sockets produced by this method advantageous or disadvantageous for amputees compared to the sockets produced by the conventional method? These results will provide guidance for units and centres that produce both above-knee and below-knee prostheses. For this purpose, we investigated whether there are differences between amputees fitted with conventional sockets and those fitted with computer-aided design/computer-aided manufacturing sockets in terms of their clinical characteristics and quality of life. Material and Method: In total, 56 patients, 28 fitted with a conventional socket (CS group) and 28 fitted with a computer-aided design/computer-aided manufacturing socket (CAD/CAM group), were included in the study. The duration of daily prosthetic use, walking time with the prosthesis, walking distance with the prosthesis, walking time with the prosthesis without pain, time of adaptation to the prosthesis, causes of amputation, and manufacturing and fitting time of the prosthesis were investigated. Quality of life was evaluated using the 36-item Short-Form Health Survey (SF-36) and Turkish version of the Trinity Amputation and Prosthesis Experience Scales (TAPES). Pain was evaluated using the visual analogue scale (VAS). Results: General and mental health statuses were somewhat better in the CAD/CAM group. Results were more favourable in the CAD/CAM group for the other items of the Short-Form 36 (SF-36) questionnaire (p > 0.05). The CAD/CAM group performed better in restriction of activity subscale (p m 0.012). There were no statistically significant differences between the groups regarding other parameters of TAPES (p > 0.05). The daily walking time with the prosthesis was higher in the CAD/CAM group than in the CS group (statistically significant; p = 0.020). The manufacturing and fitting time of the prosthesis was significantly different between the CAD/CAM and CS groups (p = 0.017). The VAS pain score was significantly lower in the CAD/ CAM group (p < 0001). Discussion: Prosthetic sockets manufactured for above-knee amputees using the CAD/CAM method yielded some better outcomes than those manufactured with conventional methods in terms of quality of life.Öğe Frequency of fibromyalgianess in patients with rheumatoid arthritis and ankylosing spondylitis: A multicenter study of Turkish League Against Rheumatism (TLAR) network(Turkish League Against Rheumatism, 2023) Kozanoglu, Erkan; Kelle, Bayram; Alayli, Gamze; Kuru, Omer; Firat, Sibel cubukcu; Demir, Ali Nail; Karakoc, MehmetObjectives: This study aimed to evaluate the frequency of fibromyalgianess, fibromyalgia syndrome (FS), and widespread pain in patients with rheumatoid arthritis (RA) and ankylosing spondylitis (AS) and their relationship with clinical and demographic parameters.Patients and methods: This cross-sectional multicenter trial was performed in 14 centers across Turkiye between June 2018 and November 2019. Out of 685 patients recruited from the accessible population, 661 patients (342 RA, 319 AS; 264 males, 397 females; mean age: 48.1 +/- 12.9 years; range, 17 to 88 years) met the selection criteria. In these cohorts, those who did not meet the criteria for FS and had widespread pain (widespread pain index >= 7) were evaluated as a separate group. Clinical status and demographic parameters of patients in both cohorts were evaluated as well as the evaluations of RA and AS patients with widespread pain (widespread pain index >= 7) and RA and AS patients with FS groups. In addition, correlations between polysymptomatic distress scale (PSD) scores and Visual Analog Scale (VAS), Simplified Disease Activity Index (SDAI), Clinical Disease Activity Index (CDAI), and Disease Activity Score using 28 joint counts for RA patients and VAS, Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), and Ankylosing Spondylitis Disease Activity Score (ASDAS) for AS patients were analyzed.Results: Frequencies of patients with FS and patients who had PSD scores >= 12 were 34.1% and 44.4% in all RA patients, respectively. Moreover, FS and PSD scores >= 12 were found in 29.2% and 36.9% of all AS patients, respectively. PSD scores of RA patients with FS were higher than all RA patients and RA patients with widespread pain. SDAI and CDAI scores of RA patients with FS were higher than all RA patients and RA patients with widespread pain. Similarly, PSD scores of AS patients with FS were higher than all AS patients and AS patients with widespread pain. ASDAS-erythrocyte sedimentation rate and BASDAI scores of AS patients with FS were found higher than all AS patients and AS patients with widespread pain.Conclusion: Disease activity scores, including pain in RA and AS, were higher in the presence of FS or fibromyalgianess. It may be related to clinical parameters, but cohort studies with long-term follow-up are needed to reveal causality. Additionally, to avoid overtreatment, coexistence of fibromyalgianess should be kept in mind in patients who have inflammatory diseases such as RA and AS, particularly with intractable widespread pain.Öğe HIGH OCCURRENCE OF METABOLIC SYNDROME IN PATIENTS WITH RHEUMATOID ARTHRITIS(Oxford Univ Press, 2011) Karakoc, Mehmet; Batmaz, Ibrahim; Tahtasiz, Mehmet; Nas, Kemal; Cevik, Remzi; Tekbas, Ebru; Yildiz, Ismail[Abstract Not Available]Öğe Metabolic Syndrome in Patients With Ankylosing Spondylitis(Elmer Press Inc, 2011) Batmaz, Ibrahim; Karakoc, Mehmet; Sariyildiz, Mustafa Akif; Yazici, Selma; Tahtasiz, Mehmet; Atilgan, Zuhal; Cevik, RemziBackground: The objective of this study is to investigate the presence of metabolic syndrome (MS) in patients with ankylosing spondylitis (AS) and to evaluate its relationship with the clinical parameters. Methods: Fifty patients who presented to the Dicle University School of Medicine, Physical Therapy and Rehabilitation Outpatient Clinic and were diagnosed with AS according to the 1984 New York criteria were enrolled in this study. The control group consisted of 44 healthy control subjects. Assessment of the MS was made according to the diagnostic criteria specified in the National Cholesterol Education Program Adult Treatment Panel III Report (NCEP ATP III). Functional status and disease activity were evaluated using the Bath Ankylosing Spondylitis Functional Index (BASFI) and the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) for AS. Results: MS was observed in 6 out of the 50 AS patients (12%) and in 2 out of the 44 controls (4.5%) (P > 0.05). However, the HDL cholesterol level (P = 0.006) was found as significantly lower in AS patients than the controls. No statistically significant differences were observed in the disease duration and functional and clinical activity indices between the AS patients with and without MS. Conclusions: Although the frequency of MS was observed to be higher in patients with AS than the controls in this study, the differences were statistically insignificant between the two groups.Öğe METABOLIC SYNDROME IN PATIENTS WITH ANKYLOSING SPONDYLITIS(Oxford Univ Press, 2011) Batmaz, Ibrahim; Karakoc, Mehmet; Yazici, Selma; Cevik, Remzi; Nas, Kemal; Sarac, Aysegul Jale; Atilgan, Zuhal[Abstract Not Available]Öğe Rehabilitation in spinal infection diseases(Baishideng Publishing Group Inc, 2015) Nas, Kemal; Karakoc, Mehmet; Aydin, Abdulkadir; Ones, KadriyeSpinal cord infections were the diseases defined by Hypocrite yet the absence of modern medicine and there was not a real protocol in rehabilitation although there were many aspects in surgical treatment options. The patients whether surgically or conservatively treated had a lot of neurological, motor, and sensory disturbances. Our clinic has quite experience from our previous researchs. Unfortunately, serious spinal cord infections are still present in our region. In these patients the basic rehabilitation approaches during early, pre-operation, post-operation period and in the home environment will provide significant contributions to improve the patients' sensory and motor skills, develop the balance and proriocaption, increase the independence of patients in daily living activities and minimize the assistance of other people. There is limited information in the literature related with the nature of the rehabilitation programmes to be applied for patients with spinal infections. The aim of this review is to share our clinic experience and summarise the publications about spinal infection rehabilitation. There are very few studies about the rehabilitation of spinal infections. There are still not enough studies about planning and performing rehabilitation programs in these patients. Therefore, a comprehensive rehabilitation programme during the hospitalisation and home periods is emphasised in order to provide optimal management and prevent further disability.Öğe Serum relaxin levels in benign hypermobility syndrome(Ios Press, 2015) Em, Serda; Oktayoglu, Pelin; Bozkurt, Mehtap; Caglayan, Mehmet; Karakoc, Mehmet; Ucar, Demet; Verim, SabahattinOBJECTIVE: In this study, we investigated the activity of serum relaxin in female patients with benign joint hypermobility syndrome (BJHS), locomotor system findings accompanying BJHS, and its relation to relaxin. METHODS: Into the study, female patients with BJHS and healthy women as the control group were included. The patients were diagnosed by using the Brighton 1998 criteria. Examination of the locomotor system for study groups were performed. Serum relaxin levels of both patient and control group were measured. RESULTS: There were 48 female patients with BJHS and 40 healthy women in the study. With respect to the control group, the level of serum relaxin was higher in the patients (47.1 +/- 20.3, 34.4 +/- 22.1; p > 0.05). Again compared with the control group, arthralgia (p = 0.00), myalgia (p = 0.01), shoulder impingement syndrome (p = 0.05), pes planus (p = 0.01), and hyperkyphosis (p = 0.000) were higher in the patients. The level of relaxin median was significantly higher in the patients with pesplanus and hyperkyphosis than those who did not have them (p = 0.05, p = 0.01, respectively). CONCLUSIONS: Although serum relaxin level is not considered a causative factor for BJHS, the significant increases found in those patients with hyperkyphosis and pes planus suggest the hypothesis that relaxin has a limited and indefinite role in patients with BJHS.Öğe Sleep quality and associated factors in ankylosing spondylitis: relationship with disease parameters, psychological status and quality of life(Springer Heidelberg, 2013) Batmaz, Ibrahim; Sariyildiz, Mustafa Akif; Dilek, Banu; Bez, Yasin; Karakoc, Mehmet; Cevik, RemziThe aim of this study is to investigate sleep quality in patients with ankylosing spondylitis (AS) and to evaluate the relationship of the disease parameters with sleep disturbance. Eighty AS patients (60 males and 20 females) fulfilling the modified New York criteria, and 52 age- and gender-matched controls (33 males and 19 females) were enrolled in the study. Sleep quality was assessed using the Pittsburgh Sleep Quality Index (PSQI). Pain was measured by visual analogue scale. The disease activity and functional status were assessed by the Bath AS disease Activity Index and the Bath AS Functional Index. The Bath AS Metrology Index was used to evaluate mobility restrictions, and the Bath AS Radiology Index was employed to evaluate the radiological damage. The psychological status and quality of life were assessed with the hospital anxiety-depression scale and AS quality of life scale. The patients with AS had significantly more unfavourable scores in the subjective sleep quality, habitual sleep efficiency domains (p < 0.001) and the total PSQI score (p < 0.05). Poor sleep quality (total PSQI score) was positively correlated with increased pain, poor quality of life, higher depressed mood, higher disease activity and mobility restrictions. Pain was also an independent contributor to poorer sleep quality (p = 0.002). The sleep quality is disturbed in patients with AS. The lower quality of sleep is greatly associated with the pain, disease activity, depression, quality of life and increased limitation of mobility.Öğe Sockets Manufactured by CAD/CAM Method Have Positive Effects on the Quality of Life of Patients With Transtibial Amputation(Lippincott Williams & Wilkins, 2017) Karakoc, Mehmet; Batmaz, Ibrahim; Sariyildiz, Mustafa Akif; Yazmalar, Levent; Aydin, Abdulkadir; Em, SerdaObjective Objective: Patients with amputation need prosthesis to comfortably move around. One of the most important parts of a good prosthesis is the socket. Currently, the most commonly used method is the traditional socket manufacturing method, which involves manual work; however, computer-aided design/computer-aided manufacturing (CAD/CAM) is also being used in the recent years. The present study aimed to investigate the effects of sockets manufactured by traditional and CAD/CAM method on clinical characteristics and quality of life of patients with transtibial amputation. Design The study included 72 patients with transtibial amputation using prosthesis, 36 of whom had CAD/CAM prosthetic sockets (group 1) and 36 had traditional prosthetic sockets (group 2). Amputation reason, prosthesis lifetime, walking time and distance with prosthesis, pain-free walking time with prosthesis, production time of the prosthesis, and adaptation time to the prosthesis were questioned. Quality of life was assessed using the 36-item Short Form Health Survey questionnaire and the Trinity Amputation and Prosthesis Experience Scales. Results Walking time and distance and pain-free walking time with prosthesis were significantly better in group 1 than those in group 2. Furthermore, the prosthesis was applied in a significantly shorter time, and socket adaptation time was significantly shorter in group 1. Except emotional role limitation, all 36-item Short Form Healthy Survey questionnaire parameters were significantly better in group 1 than in group 2. Trinity Amputation and Prosthesis Experience Scales activity limitation scores of group 1 were lower, and Trinity Amputation and Prosthesis Experience Scales satisfaction with the prosthesis scores were higher than those in group 2. Conclusion Our study demonstrated that the sockets manufactured by CAD/CAM methods yield better outcomes in quality of life of patients with transtibial amputation than the sockets manufactured by the traditional method.Öğe TRACE ELEMENTS LEVELS AND THEIR RELATIONS WITH CLINICAL FINDINGS AND QOL IN FIBROMIYALGIA(Oxford Univ Press, 2011) Nas, Kemal; Demircan, Zeynep; Karakoc, Mehmet; Yuksel, Uyan; Cevik, Remzi[Abstract Not Available]
