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Öğe Etiologic, Clinical and Laboratory Evaluation of Acute Respiratory Tract Infections in Childhood(Reial Acad Medicina Illes Balears, 2024) Onur, Hakan; Karabel, Musemma Alagoz; Mermutluoglu, Nihat; Onu, Arzu RahmanaliAim: We aimed to assess the agents causing acute respiratory tract infections in both outpatient and inpatient settings during the pandemic period, considering etiological, clinical, and laboratory findings. Materials and methods: Our study was a prospective single-center and epidemiologic study and included children admitted to the emergency department or outpatient clinic of our hospital with respiratory tract infection findings between 2020 and 2023. Children (up to seven years of age), who presented to the emergency / outpatient clinic with respiratory tract infection findings were included in the study. The children's clinical, demographic, epidemiological, laboratory, and clinical data were retrieved via our hospital's computerized medical registration system. The demographic information of the patients was noted from the hospital records. Data from laboratories on children were compared. Results: A total of 377 children were included in the study. 308 patients received inpatient treatment, while 69 children were followed up as outpatients. Among the cases, respiratory PCR analysis revealed no isolated pathogens in 154 instances, classified as pathogen-negative. When inpatients and outpatients were compared, it was observed that hospitalizations were less frequent, especially in younger patients (p<0.001). There was a weak correlation between pathogen positivity and platelet count. In hospitalized patients, platelet count and lymphocyte count increases were again weakly correlated with hospitalization (r=0.113, p:0.047 and r=0.228, p<0.001, respectively). In the evaluation of all patients, it was found that there was an increase in the number of pathogens grown in respiratory PCR with a decrease in PDW value. (p=0.015). Platelet count was higher in pathogen positive children (p<0.001). PDW value was lower in pathogen positive cases (p=0.003). Conclusion: when diagnosing children with severe respiratory infections, the detectability of viral nucleic acids plays a significant role. For these highly sensitive diagnostic tests to be used optimally, primary viral infections must be distinguished from bacterial superinfectionÖğe The Evaluation of Patients with Cystic Fibrosis in Terms of Depression(Reial Acad Medicina Illes Balears, 2024) Ucar, Fesih; Karabel, Musemma Alagoz; Sen, Velat; Uzel, Veysiye Hulya; Ipek, Rojan; Akar, AsumanIntroduction and Objective: Cystic Fibrosis (CF) is a chronic, progressive and fatal genetically inherited severe disease. Major depressive disorder (MDD) is a serious mental disorder that sometimes involves suicidal thoughts and death can occur when suicide is committed. The prevalence of depression has increased in CF patients. In our study, CF patients who were followed up monthly were investigated in terms of depression. Materials and Methods: The study group consisted of children aged 10-18 years with CF and the control group consisted of age- and gender-matched healthy children. Demographic data and depression status of the groups were analysed prospectively. The depression scale for children (DSC), which has been proven to be valid and reliable, was used for the diagnosis of depression. The total score obtained according to the DSC and the presence of depression according to the DSC were recorded. Results: Sixty per cent of the study group (n=30) and 70 per cent of the control group (n=30) were male (n=21), and the distribution was similar. History of psychiatric outpatient clinic, total score of the DSC, body mass index (kg/m(2)), consanguinity status between parents and total sleep duration were statistically significantly different between the groups (p<0.05). There was no statistically significant difference in the presence of depression, suicidal ideation, educational status, family type, place of residence, smoking exposure and parental psychiatric history. Although not statistically significant, there were numerically increased depressive symptoms and tendencies in the study group compared to the control group. Conclusion: CF is a chronic disease and the risk of depression is increased in CF patients. In addition to medical treatments, it is important to protect mental health. Adequate mental health support improves the physical symptoms of the disease and increases patient and family compliance with treatment. In conclusion, we think that it is important to perform routine mental health screening during the disease process.