Yazar "Kara, Ismail Hamdi" seçeneğine göre listele
Listeleniyor 1 - 12 / 12
Sayfa Başına Sonuç
Sıralama seçenekleri
Öğe Bacteremia caused by Stenotrophomonas maltophilia in a dialysis patient with a long-term central venous catheter(Univ Chicago Press, 2006) Kara, Ismail Hamdi; Yilmaz, Mehmet Emin; Sit, Dede; Kadiroglu, Ali Kemal; Koekoglu, Oemer Faruk[Abstract Not Available]Öğe Chronic Fatigue Syndrome among nurses and healthcare workers in a research hospital in Turkey(Soc Personality Res Inc, 2008) Kara, Ismail Hamdi; Demir, Dogan; Erdem, Oezguer; Sayin, Guelfer Topcu; Yildiz, Nuran; Yaman, HakanChronic fatigue syndrome (CFS) among nurses and healthcare workers was evaluated via a questionnaire examining CFS, sociodemographic factors, lifestyle, work capacity and education. The criteria of the Centers for Disease Control were applied. One hundred and eighty-three nurses and 18 healthcare workers (mean age 29.04 +/- 5.31 years) participated. More than half of cases (n = 116, 57.7%) complained of fatigue. Thirty-six cases (17.9%) fully matched the criteria of the CDC for CFS. High income level (> $400/month) (p = 0.005) and overworking (> 8 hr/day) (p = 0.017) had a significant effect on CFS [high income (OR: 9.60, CI, 95%: 1.98 - 46.54) and overworking (OR: 7.66, CI, 95%: 1.44 - 40.92), respectively]. CFS was also related to being under 35 years old.Öğe The Comparing of the sociodemographic features, anthropometric and biochemical parameters of the cases with Metabolic Syndrome, Type 2 Diabetes Mellitus and healthy controls(Duzce Univ, 2010) Demir, Dogan; Bucaktepe, Gamze Erten; Kara, Ismail HamdiAim: In this study, it was aimed to compare the sociodemographic features and biochemical parameters of the patients with Metabolic Syndrome (MS) and Type 2 Diabetes Mellitus (DM) with control group. Material and Method: In this study, among the patients who applied to Dicle University Faculty of Medicine Family Practice outpatient policlinic, 32 patients with MS, 21 patients with Type 2 DM were taken and 21 patients were selected for control group. Patients with MS and Type 2 DM were compared with control group according to their sociodemographic, anthropometric and biochemical parameters. Results: Of 74 patients applied to the study, 29 were female and 45 were male. There weren't any statistical differences about gender, education, diet and exercise between the three groups (respectively, p=0,224, p=0,216, p=0,234 and p=0,504). W/H ratios, BMI and ages were statistically meaningful between three groups (respectively p=0,001, p=0,005 and p=0,0001). Patients with MS had higher W/H ratios and BMI values. HOMA-IR values were increasing with age (r=0,295, p= 0,011), also there was a positive correlation between HOMA-IR and T. CHOL/HDL ratios (r=0.296, p=0.010). Conclusion: While HOMA-IR values were significantly higher in Type 2 DM group, any differences between MS and control group were not detected. Also in both two study groups, HOMA-IR values were increasing with age and there was a positive correlation between HOMA-IR and T. CHOL/HDL ratios. BMI values were positively correlated with systolic and diastolic blood pressures and also W/h ratios. TG values were increasing with W/H ratios.Öğe Delirium With a Single Dosage of Acyclovir in a Continuous Ambulatory Peritoneal Dialysis Patient: Case Report(Turk Nefroloji Diyaliz Transplantasyon Dergisi, 2007) Kayabasi, Hasan; Kadiroglu, Ali Kemal; Kara, Ismail Hamdi; Sit, Dede; Yilmaz, M. EminValacyclovir is an effective oral agent for the treatment of herpes virus infection, however, the pharmacokinetics of the drug are altered in renal failure. It is increasingly recognized that dose adjustment of oral valacyclovir in renal failure is necessary to avoid neurotoxicity. We studied this drug in a continuous ambulatory peritoneal dialysis (CAPD) and immunocompromised patient. She developed neurotoxicity with an adjustment dosage of valacyclovir for a cutaneous zoster infection. The elimination half-time (15 h) was similar to that reported for end-stage renal disease patients, while the steady-state volume of distribution (85 l) and the area under the curve concentration (127 mg/l.h) were greater. The mean CAPD dialysance was only 5.27 ml/min with less than 1% of an administered dose being recovered in the 24-hour dialysate. 48 h after interrupting treatment, she recovered normal neurological status and 500 mg of valacyclovir every 2 days was effective and well tolerated.Öğe Effects of Photodynamic Therapy With Verteporfin for the Treatment of Chronic Central Serous Chorioretinopathy: An Uncontrolled, Open-Label, Observational Study(Elsevier, 2010) Sakalar, Yildirim Bayezit; Keklikci, Ugur; Unlu, Kaan; Alakus, Mehmet Fuat; Kara, Ismail HamdiBACKGROUND: Central serous chorioretinopathy is an idiopathic disorder that leads to serous neurosensory retinal detachment. The disorder is usually self-limited and resolves spontaneously; however, sometimes neurosensory retinal detachment persists. This form of the disorder is called chronic central serous chorioretinopathy (CCSC). OBJECTIVE: The aim of this study was to assess the effects of photodynamic therapy (PDT) on visual acuity with full-dose verteporfin for CCSC. METHODS: The eyes of patients with CCSC were included in the study. Ophthalmic examination including best-corrected visual acuity (BCVA), fundus examination, fluorescein angiography, and optical coherence tomography was performed before treatment and at 1, 3, 6, 9, and 12 months. PDT with full-dose verteporfin (6 mg/m(2) of body surface area) was applied only to areas of active leakage. BCVA was converted to a log of the minimum angle of resolution (logMAR) equivalent for statistical analysis. Central foveal thickness and BCVA between baseline and follow-up were compared. RESULTS: Seventeen eyes of 16 patients (13 males, 3 females; mean [SD] age, 39.75 [7.51] years; mean duration of follow-up, 13.06 [1.82] months) were used in the study. The mean (SEM) logMAR BCVA was 0.26 (0.07) at baseline and 0.04 (0.02) at 12 months. Mean logMAR BCVA values at baseline (0.259) and after treatment (0.112, 0.053, 0.047, 0.041, and 0.041 at 1, 3, 6, 9, and 12 months, respectively) differed significantly (P = 0.006, P = 0.005, P = 0.005, P = 0.005, and P = 0.005). There was a significant difference in the mean central foveal thickness at the final visit (169 pm) compared with the baseline value (383 pm; P < 0.001). BCVA decreased in one eye (20/20 vs 20/25) and persisted during follow-up; in the other 16 eyes, BCVA either increased (n = 10) or remained stable (n = 6). CONCLUSIONS: In this small, open-label study, patients with CCSC treated with a single course of PDT with full-dose verteporfin had significant improvement from baseline in BCVA and resolution of subretinal fluid accumulation and active leakage. Treatment was generally well tolerated, but one patient had worsening in BCVA. (Curr Thor Res Clin Exp. 2010;71:173-185) (C) 2010 Excerpta Medica Inc.Öğe Effects of Ramadan Fasting on Biochemical and Hematological Parameters and Cytokines in Healthy and Obese Individuals(Mary Ann Liebert Inc, 2011) Unalacak, Murat; Kara, Ismail Hamdi; Baltaci, Davut; Erdem, Ozgur; Bucaktepe, P. Gamze ErtenBackground: The typical nutritional plan in Ramadan may have beneficial influences on the inflammatory state, as well as on metabolic and anthropometric parameters. We aimed to investigate the effects of Ramadan fasting on biochemical and hematological parameters and cytokines in healthy and obese individuals. Methods: This study was performed during the Ramadan holy month (September and October 2007). The study group consisted of 10 obese males and the control group consisted of 10 males with a normal body mass index (BMI), who were admitted to the Family Medicine Outpatient Clinic of Dicle University Medical Faculty in Diyarbakir, Turkey, and who indicated that they were going to fast throughout the entire month of Ramadan. Individuals with any acute or chronic disease or medication during the study were excluded. Height, weight, BMI, and waist and hip circumferences were measured. High-density lipoprotein cholesterol (HDL-C) and low-density lipoprotein cholesterol (LDL-C), triglyceride (TG), urea, creatinine, insulin, total protein, albumin, C-reactive protein (CRP), lactic dehydrogenase (LDH), alanine aminotransferase (ALT), aspartate aminotransferase (AST), and cytokine levels were evaluated. Results: The average age of the participants was 27.4 +/- 5.2 years. Of the study group, 7 fulfilled the criteria of metabolic syndrome. Significant weight reduction, significant decrease in BMI, and significant decrease of homeostasis model assessment of insulin resistance (HOMA-IR) and fasting blood glucose (FBG) were observed in study group; weight and BMI reduction were insignificant and no significant change was observed in FBG levels, but a significant increase was observed in HOMA-IR in the control group. Post-Ramadan systolic and diastolic blood pressure values, serum white blood cells (WBC) count, interleukin-2 (IL-2), IL-8, tumor necrosis factor-alpha (TNF-alpha, TG, and ALT levels were significantly lower in both groups compared to pre-Ramadan values. Conclusion: Ramadan fasting has beneficial influences on the inflammatory state, as well as metabolic and anthropometric parameters.Öğe The evaluation incidence and risk factors of mortality among patients with end stage renal disease in Southeast Turkey(Taylor & Francis Ltd, 2008) Sit, Dede; Kadiroglu, Ali Kemal; Kayabasi, Hasan; Kara, Ismail Hamdi; Yilmaz, Zulfukar; Yilmaz, M. EminAim. End stage renal disease (ESRD) presents with higher morbidity and mortality with respect to the general population. In recent study, the causes of mortality and associated risk factors in ESRD have been evaluated. Materials and Methods. In this study, 1538 patients diagnosed with ESRD in 10-year period were evaluated retrospectively. The patients were divided as dead (group 1) and alive (group 2). The patients' demographic features, causes of death, comorbidity at hospitalization, hematological and biochemical analyses, creatinine clearance at the beginning of hospitalization, daily urine volume, blood gas results, CRP value as inflammatory marker, ejection fraction, interventricular septum diameter, left ventricle posterior wall end-diastolic diameter, and left atrium diameter determined with echocardiography were recorded. Results. Mortality ratio of ESRD patients in a 10-year period was 14.1%. While the general mean age of all patients was 54.7 +/- 16.6 and male/female ratio was 781/757, these ratios were 66.3 +/- 21.8 and 114/103 in Group 1 and 52.8 +/- 21.7 and 667/654 in Group 2. One or more comorbid pathologies were present in 82.9% of Group 1. The most common cause of mortality was cardiovascular diseases (CVD), and the most common cause of comorbidity was infections. Older age, anemia, absence of residual renal function, hypoalbuminemia, inflammation, impaired Ca and P metabolism, and left ventricular hypertrophy were significantly higher in Group 1 than in Group 2. Conclusion. CVD are the most important preventable causes of morbidity and mortality in all stages of chronic kidney disease. Taking precaution against CVD and the associated complications will provide a positive contribution in reducing morbidity and mortality among ESRD patients.Öğe An evaluation of articles in international peer-reviewed publications in Turkish family medicine(Int Scientific Literature, Inc, 2007) Yaman, Hakan; Kara, Ismail HamdiBackground: Scientific publication in Turkish family medicine (FM) has currently increased and a systematic assessment of the qnantity and quality of the published research is the aim of this study. Material/Methods: The data were obtained from the Institute for Scientific Information Citation Databases (SCI, SCI-Expanded, SSCI, and A&HSCI) and the period between 1975-2005 was searched. Key words such as family practice, family medicine, primary care, primary medical care, and Turkey were used and publications were classified according to the type of research, the number of authors, first authorship, the number of citations, and address. The classification was performed by two investigators and the inter-rater-reliability was found to be Cramer's V=0.79 (p < 0.05). Results: One hundred five publications were found. Publications were evident since the year 1991 and showed all increase with the year 2001. The median number of authors of the publications was five (range 1-8), and family physicians were generally the second authors (range: 1-7). The predominant types of publication was research articles (n=72, 69%), and the leading types of research were surveys (n=29, 28%) and case-control studies (n=21, 23%). The median citation number of publications per article was 0.89 (range: 0-13). Conclusions: A recent increase in publication in international peer-reviewed journals was observed. Mostly research articles were published, but randomized controlled trials were in the minority. More emphasis on developing a research capacity in family medicine might help to optimize research activities in Turkey.Öğe Habitual tea drinking and bone mineral density in postmenopausal Turkish women(Verlag Hans Huber, 2007) Kara, Ismail Hamdi; Aydin, Serpil; Gemalmaz, Ayfer; Akturk, Zekeriya; Yaman, Hakan; Bozdemir, Nafiz; Kurdak, HaticeAim: In this epidemiological report, we assessed the prevalence of osteopenia and osteoporosis (OP) in postmenopausal Turkish women and the relationship between body mass index (BMI), and some nutritional factors (habitual tea, coffee, tobacco, and milk product consumption) with OP. Methods: This multicenter study was done in postmenopausal women residing in five big cities, in four different regions of Turkey between August and November 2005. An inclusion criterion was being in the postmenopausal period for at least 12 months. A semi-structured questionnaire was completed by face-to-face interview, consisting of closed- and open-ended questions about demographic characteristics, nutritional status, and habits with two or more choices as possible responses. Bone mineral density (BMD) measurements were performed with a MetriScan (R) Densitometer (Alara Inc., Ca, USA). Results: Seven hundred twenty-four women were included in the study. The mean age was 57.6 +/- 9.6 years, and mean age at natural menopause was 46.4 +/- 5.6 years. Of the participants, 51% were illiterate. According to WHO classification; 42.5% were normal in terms of BMD, 27.2% had osteopenia, and 30.2% had OP. Women with high education levels had better T-scores (p = 0.0 19). Increase in BMI also had a positive effect on T-scores (p < 0.0001). A linear correlation was found between age (r= -0.386, p < 0.000 1), BMI (r = -0.175, p < 0.0001), and education (r = -0.317, p < 0.0001), with T-scores. The T-scores of women who consumed tea on a regular basis were found to be higher than non-consumers (-1.51 +/- 1.68 vs. -1.09 +/- 1.66; p = 0.070) [when smokers, those who received hormonal therapy (HT), and those > 65 years were excluded]. Conclusion: OP was determined in 1/3 of the women. Advanced age (> 65) and being illiterate were negative factors, while high education levels, being overweight, and being treated with HT had a positive effects on BMD. Habitual tea drinking also may have a positive effect on BMD. However, tea drinking was not found to be a statistically significant factor in the present study.Öğe The prevalence and the characteristics of tuberculosis patients undergoing chronic dialysis treatment: Experience of a dialysis center in southeast Turkey(Taylor & Francis Ltd, 2008) Kayabasi, Hasan; Sit, Dede; Kadiroglu, Ali Kemal; Kara, Ismail Hamdi; Yilmaz, Mehmet EminTuberculosis remains a significant health problem for patients receiving chronic dialysis. The purpose of this study was to evaluate the prevalence, clinical characteristics, and outcomes of tuberculosis among patients with end-stage renal failure (ESRF) undergoing chronic hemodialysis and continuous ambulatory peritoneal dialysis. Between 1999 and 2006, we diagnosed 21 active tuberculosis patients among a total of 674-dialysis patient in our dialysis center (582 patients on hemodialysis and 92 patients on continuous ambulatory peritoneal dialysis program). Fourteen patients developed extrapulmonary tuberculosis (generally tuberculous lymphadenitis, n = 8) and seven patients developed pulmonary tuberculosis. All patients who developed tuberculosis after starting dialysis had low creatinine clearances and, in general, anemia and hypoalbuminemia. Three of patients greater than 40 years died. In conclusion, tuberculous lymphadenitis was the most frequent form of extrapulmonary tuberculosis in our dialysis population. If no cause is found despite extensive investigations in an end stage renal failure case with fever, loss of weight, and/or atypical lymphadenopathy, the physician should consider the possibility of tuberculosis. Finally, it was considered that ESRF is associated with depressed immune system and elevated risk of tuberculosis; thus, in this population, clinicians must evaluate patients carefully.Öğe QUS measurements in dialysis patients(Medi+World Int, 2005) Kara, Ismail Hamdi; Yilmaz, Mehmet Emin; Turgutalp, Kenan; Tuzcu, Alparslan; Kadiroglu, Ali KemalBackground: It was aimed to evaluate the bone measurements by quantitative heel ultrasound (QUS) in patients undergoing chronic haemodialysis (HD) and continuous ambulatory peritoneal dialysis (CAPD), and healthy controls. It was also aimed to investigate the relationship between weight, body mass index (BMI), smoking and parathyroid hormone (PTH) with QUS parameters. Method: Present study included 25 patients on chronic HD (Group 1), 16 patients treated by CAPD (Group 2) and 32 controls (Group 3). QUS (Hologic, Sahara bone sonometer) measured broadband ultrasound attenuation (BUA; dB/Mhz), quantitative ultrasound index (QUI; g/cm(2)), speed of sound (SOS; m/s). The WHO (1997) classification of BMI was used for weight classification. The smoking criterion was defined as smoker and non-smoker. Results: Mean age of cases was 40.2 +/- 15.5, 36.0 +/- 9.9 and 36.6 +/- 12.4 years, in groups 1, 2 and 3 (p>0.05), and mean dialysis duration time was 31.8 +/- 12.6 and 42.8 +/- 12.8 months, in groups 1 and 2 (p=0.015). Depending on the QUS parameters, both osteoporosis and osteop zenia were diagnosed in five (56%) of women and in 11 (69%) of men in HD vs in two (33%) of women and in four (40%) of men in CAPD, respectively (p=0.584). QUS measurements were not correlated with serum PTH and BMI in both HD and CAPD groups, respectively. In HD group, we found SOS to be lower ( 1526 +/- 27 vs. 1548 +/- 19 m/s, p=0.016) in smokers compared to non- smokers. There were negative correlations between smoking and QUS parameters ( r=-0.34; p=0.044). Conclusion: Our findings suggest that there is an unfavorable influence of HD and smoking on bone mineralization compared to CAPD.Öğe The ratio of HBsAg and AntiHCV Seropozitivity in pregnant and other patients admitted to Department of Obstetrics and Gynecology and their relationships with the other risk factors(Duzce Univ, 2012) Yildiz, Bahri; Bucaktepe, P. Gamze Erten; Yildiz, Ismail; Kara, Ismail HamdiObjective: In this study, it has been aimed to define and compare sociodemographic properties of patients with positive HBsAg and AntiHCV who had hospitalized between January and December 2010 at Department of Obstetrics and Gynecology, Dicle University Faculty of Medicine (DUFM). Method: In this retrospective and descriptive study, HBsAg and/or AntiHCV positive 132 patients were detected among a total of 4491 scanned patients by using chemiluminescent microparticle immunoassay (CMIA) method. Admission diagnoses, ages, sociodemographic characteristics, obstetric histories, biochemical values, babies' conditions-if they are pregnant, lengths of hospital stay and risk factors for hepatitis of these patients were identified. AntiHCV and HBsAg-positive patients were compared according to their properties listed above. Results: 46.2% of studied patients (n=61) were between the ages of 26-35 years, 67.4% (n=89) of them were admitted from rural areas and 62.9% of them had green card (n=83). Fourty six of the patients (34.9%) were admitted due to problems relating to the pregnancy complications or baby. HBsAg and AntiHCV positivity rates were determined to be 2.63% (n=118) and 0.29% (n=13), respectively. Among the pregnant women admitted to the clinic, HBsAg and AntiHCV positivity rates were determined to be 2.66% and 0.20%, respectively. Conclusion: Since taking infection at birth will increase the risk of developing a fatal complication in advancing ages, all pregnant women should be examined against preventable disease HBV. This should be done as routine antepartum examination. Carrier mothers should be enlightened on the importance of passive and active immunization after delivery of the baby.
