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    The effect of periodontal therapy on serum CRP, IL-6 levels and periodontal parameters in patients having poorly and well controlled type 2 diabetes with chronic periodontitis: A 3-month evaluation
    (2010) Dağ A.; Firat E.T.; Kadiroğlu A.K.
    Aim: To evaluate the effect of nonsurgical periodontal therapy on serum C-reactive protein (CRP), interlökin-6 (IL-6) levels and periodontal parameters in patients with poorly and well controlled type 2 diabetes with chronic periodontitis. Methods: Forty-five patients were included in the study. Of the 45, 30 had type 2 diabetes mellitus with chronic periodontitis (group 1A; poorly controlled group, n = 15, HbA1c ? 7% and group 1B; well controlled group, n = 15, HbA1c < 7%) and 15 were systemically healthy (group 2) with chronic periodontitis. Plaque index, gingival index, probing depth, clinical attachment loss, gingival bleeding index scores, serum CRP and IL-6 concentrations were measured at baseline and 3 months after the nonsurgical periodontal therapy. Results: After the nonsurgical periodontal therapy all periodontal parameters and CRP and IL-6 levels decreased significantly by the third month compared to baseline values in all groups. No statistically significant difference was determined among the groups between baseline and third-month periodontal parameters, or in CRP or IL-6 levels after nonsurgical periodontal therapy. Conclusion: Improvement in periodontal health is effective on control of systemic infection via reducing serum concentrations of CRP and IL-6 in patients with poorly and well controlled type 2 diabetes with chronic periodontitis. The effects of nonsurgical periodontal treatment seems to be independent of the degree of diabetic status. © 2010 Düzce Medical Journal.
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    Evaluation of the characteristics of patients with acute drug poisoning and clinical outcomes in a university hospital in region of southeastern Anatolia
    (2013) Kadiroğlu A.K.; Yilmaz Z.; Yildirim Y.; Ebik B.; Yildirim S.; Oto F.; Ulucan F.
    Introduction: Cases of intoxication is an important part of the patients admitted to General Internal Medicine Intensive Care Unit. The aim of this study is to present the features of patients admitted to our General Internal Medicine Intensive Care Unit with acute drug intoxication and clinical outcomes. Material and method: The data of patients with acute drug intoxication admitted to our General Internal Medicine Intensive Care Unit between June 2010 and December 2012 were analysed retrospectively. The patients' age, gender, etiology, comorbid conditions, blood pressure, arterial blood gases, hematological and biochemical parameters, treatments and clinical outcomes were evaluated. Results: 81.4% of patients were female, 18.6% were male. The mean age of the patient was 30.23 ± 15.44 years. Multi-drug poisoning (51.2%)was the most common cause among the drug poisoning. 32.5% of the patients had comorbid conditions. The most common comorbid was psychosis among the disease. Only one patient hospitalized with organophosphate intoxication was need for mechanical ventilation due to extremely secretion. Hemodialysis therapy was performed 2 times in one patient with valproic acid intoxication. Conclusion: The cases of multi-drug intoxications (51.2%) were found to be more in patients with acute drug intoxication hospitalized into the General Internal Medicine Intensive Care unit. 16.2% of our patients hospitalized with drug intoxication had psychosis.
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    A rare cause of anemia in a patient with end stage renal disease: Pulmonary hemorrhagic syndrome: Case report
    (Turkiye Klinikleri, 2007) Şit D.; Kadiroğlu A.K.; Kayabaşi H.; Büyükbayram H.; Yilmaz M.E.; Işikoğlu B.
    The association of pulmonary hemorrhagic syndrome and end stage renal disease is a rare condition. Severe anemia that occurred suddenly in a 27 years old male patient who was undergoing chronic HD program was investigated. Platelet count was normal but bleeding time was prolonged. Pulmonary hemorrhagic syndrome was considered secondary to platelet dysfunction. The diagnosis was confirmed by pulmonary biopsy. The patient was successfully treated with conservative approach. Copyright © 2007 by Türkiye Klinikleri.
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    Retrospective evaluation of brucellosis cases inhabiting in Mus province
    (2006) Şit D.; Kadiroğlu A.K.; Kayabaşi H.; Hoşoğlu S.
    The aim of this study was to evaluate the brucellosis patients inhabiting in Mus province, in Eastern Anatolia of Turkey, retrospectively. The mean age of the patients (n: 87) was 38.1±12.4 years, and 45% of them were female. The transmission route was the consumption of unpasteurized fresh cheese (in 85%), and unboiled milk (in 45%). The most common symptoms were recorded as chills (89%), fever (87%), and arthralgia (81%). Splenomegaly (71%) and hepatomegaly (63%) were the predominant physical examination signs. Diagnosis was made based on the clinical features and positive Rose-Bengal test result (93%), however, blood cultures could not be performed due to insufficient laboratory equipment. In 92% of the patients at least one complication has been detected indicating delayed admission to the hospital, while the most common complications were sacroileitis (79%) and spondylitis (44%). Streptomycin+doxycyclin, streptomycin+doxycyclin+ ciprofloxacin, and streptomycin+doxycyclin+ rifampicin combination therapies were used in 62%, 24% and 14% of the patients, respectively, for six weeks, resulting with complete cure.