Yazar "Irfan, Guzel Ali" seçeneğine göre listele

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    18F-FDG PET-CT and USG/CT in benign and malignant ovarian tumors with postoperative histopathological correlation
    (Studio K, 2011) Kuyumcuoglu, Umur; Irfan, Guzel Ali; Celik, Yusuf; Erdemoglu, Mahmut; Komek, Halil
    Objectives: The role of F-18-FDG (F-18 fluorodeoxyglucose) PET/CT** (Positron emission tomography) in the diagnosis, treatment and follow up of benign and malignant ovarian tumors had been investigated previously. The objective of the following study was to evaluate the predictive value of PET/CT in benign and malignant ovarian tumors and compare with computerized tomography and post-operative pathology. Materials and methods: In this retrospective study a total of sixty nine cases with benign or malignant pelvic masses underwent laparotomy at our clinic. Postoperative pathology of the patients was recorded and PET/CT results were compared with ultrasonography, computerized tomography and postoperative pathology. Results: The ROCs and AUCs values four predictors were shown in Figure 1. The AUCs (95 % CI) values calculated for CA 125, ultrasonography (USG), PET/CT and CT were as follows: 0.855(0.752-0.958), 0.703(0.540-0.866), 0.681(0.514-0.848) and 0.631(0.463-0.799) respectively. CA 125 has the highest AUC value in order to predict the malignant potential of the patient. USG has the highest AUC value between the imaging techniques, following PET/CT and CT. Conclusion: According to this study among four modalities that distinguish malignant potential preoperatively; CA 125 is the best parameter. USG and PET provide similar benefits in detecting malignant ovarian masses preoperatively. Both of these parameters are superior to CT. Combination of CA 125, USG and PET/CT may be useful in detecting malignant ovarian masses preoperatively, resulting in less invasive surgeries. **F-18-FDG (F-18 fluorodeoxyglucose) PET/CT will be used as the PET/CT, later in this article.
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    Dietary antioxidant levels in hyperemesis gravidarum: A case control study
    (Via Medica, 2011) Celik, Fatma; Irfan, Guzel Ali; Kuyumcuoglu, Umur; Celik, Yusuf
    Objectives: Dietary antioxidant intake decreases the risk of many diseases. Hyperemesis gravidarum (HG) is the most common eating disorder during pregnancy Therefore, the authors conducted this prospective and case control study to evaluate dietary antioxidant levels of women with HG and compare with healthy pregnant women. Material and Methods: This prospective case control study was conducted at a government hospital in the southeastern region of Turkey from February 2010 to May 2010. A total of 100 pregnant women were included into the study Dietary antioxidant levels (DAL) were measured according to the new 92-item antioxidant nutrient questionnaire developed by Satia et al (1). 50 women with HG and 50 healthy pregnant women were evaluated. Statistical analyses were carried out with statistical packages for SPSS 15.0 for Windows (SPSS Inc., Chicago, IL, USA). Results: There were no statistically significant differences between the groups regarding the age of the patients, gestational age, educational status, body height and weight (p >.05). Vitamin E, E equivalent, vitamin C, carotene and vitamin A levels were significantly lower in women with HG (p <.05). The results of logistic regression method for these variables including odds ratio (95 % CI) were as follows: 10.07(1.52-66.51), 7.37(2.66-20.41), 4.26(2.66-20.41), 3.66(2.38-5.63) and 2.75 (1.56-4.85), respectively Conclusion: According to this study vitamin E, E equivalent, vitamin C, carotene and vitamin A levels of women may play a role in the pathogenesis of HG. Therefore, diet recommendations should be given by clinicians before pregnancy