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Öğe Assessment of Serum ADMA Levels and Aortic Elastic Properties in Patients With Ankylosing Spondilitis(Elsevier Science Inc, 2013) Kaya, Hasan; Tekbas, Ebru Onturk; Ertas, Faruk; Inci, Umit; Oylumlu, Mustafa; Yuksel, Murat; Aydin, Mesut[Abstract Not Available]Öğe Assessment of serum asymmetric dimethylarginine levels and left ventricular diastolic function in patients with ankylosing spondylitis(Wiley, 2017) Inci, Umit; Yildiz, Abdulkadir; Batmaz, Ibrahim; Tekbas, EbruAim: To assess left ventricular diastolic functions and serum dimethylarginine (ADMA) concentrations, as well as the effect of different treatment strategies on ADMA concentrations and diastolic function parameters, in patients with ankylosing spondylitis (AS). Method: Sixty AS patients and 40 control subjects without classical cardiovascular (CV) risk factors were included in the study. Baseline clinical and echocardiographic variables were obtained. C-reactive protein (CRP), erythrocyte sedimentation rate (ESR) and ADMA levels were measured. Spinal mobility, disease activity and functional status were assessed using Bath Ankylosing Spondylitis Metrology Index, Bath Ankylosing Spondylitis Disease Activity Index and Bath Ankylosing Spondylitis Functional Index. Results: CRP, ESR and ADMA levels were significantly higher in the AS group as compared to the control group. Two (5%) control subjects and six (10%) AS patients met the criteria for left ventricular diastolic dysfunction (DD) on conventional Doppler echocardiography, but the difference was not statistically significant (P = 0.36). However, using tissue Doppler imaging, 12 (20%) patients in the AS group and three (8%) subjects in the control group were diagnosed with left ventricular DD (P = 0.08). The anti-tumor necrosis factor (TNF)-alpha group, conventional therapy group and control group were compared in terms of ADMA, CRP, ESR levels and echocardiographic parameters. ADMA levels were significantly lower in anti-TNF-alpha group as compared to the conventional therapy group (P < 0.001). In the control group, ADMA levels were significantly lower than both treatment groups (P < 0.001). Conclusion: Increased ADMA levels reveal impaired nitric oxide metabolism in a relatively young group of patients with AS, who have no classical CV risk factors. Anti-TNF-alpha may have beneficial effect on endothelial function in AS patients by reducing ADMA levels.Öğe The relationship between coronary collateral circulation and palmar circulation(Duzce Univ, 2013) Islamoglu, Yahya; Cil, Habib; Atilgan, Zuhal; Tekbas, Ebru; Elbey, Mehmet Ali; Inci, Umit; Ozaydogdu, NejdetCoronary collateral vessels, provide link between coronary arteries, decreased both mortality and morbidity in patients with myocardial infarction. Palmar collateral circulation locates between ulnar and radial arteries, and its adequacy can be evaluated by noninvasive tests. We aimed in this study to investigate relationship between coronary collateral circulation and palmar collateral circulation. 96 patient, detected in coronary arteries at least 70% stenosis, were included the study. Coronary collateral circulation was evaluated according to rentrop classification as adequate and inadequate collateral circulation. Hand circulations of the patients were evaluated with Allen Test and Modified Allen Test. Incomplete palmar arch were detected in patients with adequate and inadequate coronary collateral circulation 22% and 29%, respectively. There was no significant different between two groups according to presence of incomplete or complete palmar circulation. In our study, we demonstrated that there was no relationship between coronary collateral circulation and palmar collateral circulation.Öğe An unusual co-anomaly: multiple coronary-cameral fistulas and left main coronary artery arising from the right sinus of Valsalva(Turkish Soc Cardiology, 2013) Yildiz, Abdulkadir; Inci, Umit; Akyuz, Abdurrahman; Oylumlu, Mustafa[Abstract Not Available]
