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    Alagille Syndrome: A review
    (2013) Callea M.; Bahsi E.; Montanari M.; Ince B.; Mancini G.E.; Yavuz Y.; Radovich F.
    Alagille Syndrome (AGS) is a genetically determined multisystem disorder affecting liver, hearth, eyes, skeleton and facies, less commonly kidney and CNS. The prognosis depends on the severity of the associated anomalies. The liver pathology plays a central role in that most clinical complications are due to long standing cholestasis as a consequence of lack of bile excretion secondary to paucity/absence of interlobular bile ducts. That results in hyperbilirubinemia, hypercholesterolemia, hypertriglyceridemia, fat and liposoluble vitamin malabsorption, pruritus and cutaneous xanthoma. Liver transplantation represents the only curative therapy for the liver pathology. Most hepatic symptoms reverse after liver transplantation. Therapeutical education for oro-dental hygiene is required before and after liver transplantation. The green pigmentation of teeth requires dental rehabilitation. This paper reviews the clinical manifestations of AGS with special regard to the cephalic district, and highlights the necessity for a multidisciplinary approach in order to minimize complications and to ameliorate the quality of life in AGS patients.
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    Can exposure to manganese and extremely low freIuency magnetic fields affect some important elements in the rat teeth?
    (2012) Ince B.; Akdag Z.; Bahsi E.; Erdogan S.; Celik S.; Akkus Z.; Dalli M.
    Background: Length and level of exposure to electromagnetic fields (EMFs) is increasing in association with the widespread use of electrical and electronic devices and technological progress. The undesirable effects of extremely low freIuency magnetic fields (ELF-MFs) on health have attracted considerable interest. Materials and Methods: Sixty-four fourmonth- old male Wistar rats divided into eight groups of eight rats each were used. Seven groups were exposed to varying dosages of manganese (Mn) and a 50 Hz magnetic field (MF) of approximately 1 mT, while the last group was set aside as the cage control group and not subjected to any procedure. This study was intended to investigate the interactions between the application of MF and Mn and the elements Ca, Zn, Mg, and P thought to be involved in caries, in rat teeth. Results: Levels of Ca, Mg, Zn, and P in the experimental group rats were different to those in the control group. Conclusions: The results demonstrate that ELFMF and Mn can have significant effects on levels of elements in rat teeth. Further experimental and epidemiological studies of ELF-MF and Mn are needed in order to evaluate their dental effects.
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    The evaluation of reasons for replacement of amalgam and composite
    (2013) Bahsi E.; Ince B.; Dalli M.; Sahbaz C.; Colak H.; Acikan I.; Aslan N.
    Amalgam and composite restorations take prime place in restorative dental practices. Over time, restorations are replaced for various reasons. This study aimed to evaluate the reasons for restoration replacement of patients presenting at Dicle University, Dental Faculty, Restorative Dentistry Clinic. The study comprised 705 patients (402 female, 303 male) who presented at the dental clinic for routine dental treatment. Without taking gender into consideration, patients aged 15-80 who were determined to have amalgam and composite filling problems were included in the study. The patients were allocated to 5 groups according to age: Group 1, 16-25 years, Group 2, 26-35 years, Group 3, 36-45 years, Group 4, 46-55 years, Group 5, 56 years and over. The failure of the fillings was diagnosed from clinical and radiological evaluation results. The age, gender and reason for the replacement of the restoration were recorded for all patients. The obtained data was evaluated with Student's t test and a difference was determined between the age groups. Of 705 restorations, 378 (53.62%) were amalgam and 327 were composite (46.38%). When the reasons for replacement of restorations were examined the primary reason was secondary caries (30.78%), followed by fracture of the restoration (17.6%) and overflowing filling (15.46%). A significant difference was found between the age groups in terms of the parameter of reason for restoration replacement (p<0.05). To determine between which age groups this difference was more significant, the Tukey HSD test was applied as a multiple comparison test. The most significant reason for replacement of amalgams and composites was found to be secondary caries. The factor of gender had no effect on the reasons for replacement of the restoration. Failure of the restoration was seen to be greater in the 16-25 age group.
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    Hypohydrotic ectodermal dysplasia: A clinical case report
    (University of Dicle, 2014) Callea M.; Paglia M.; Bahsi E.; di Stazio M.; Ince B.; Fedele G.; Yavuz Y.
    In times where rare diseases, mostly of genetic offspring, lead research to carry out genetic counselling to better understand the pathogenetic role of the diseases, with chances to develop alternative therapy respect than the multyspecialistic and symptomatic approach, we report on a case of X linked Hypohidrotic Ectodermal Dysplasia, knowing the importance of research, basic to gene therapy, aware of the recent novelties which might drive to an improvement of the symptoms in an alternative way; still as Paediatric Dentists, awaiting for these magic result we carry out an oral rehabilitation reporting step by step the treatment achieving a very good compliance in term of smile, occlusion and aesthetics concerning the patient.
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    A multi-disciplinary approach to the treatment of dilacerated lower incisor teeth with periapical lesion: 2 years follow-up
    (University of Dicle, 2015) Bahsi E.; Yilmaz H.Y.; Ince B.; Cellik O.; Oztekin F.; Acikan I.
    Periapical lesions are frequently encountered in dentistry and are a condition which can cause loss of teeth. Diagnosis is made on the basis of the anamnesis, radiographic findings and by the examination of percussion and the vitality of related teeth. Histopathological findings generally conform with radiographic findings. The case is here presented where, following endodontic treatment of the right mandibular first incisor with dilaceration and periapical lesion, and the left mandibular first incisor with periapical lesion, root tip resection was applied. At the end of 6 months observation, as there was improvement in the lesion root tip surgery was applied. During a 2-year follow-up period, the lesion has diminished and recovery has been observed in the bone.