Yazar "Inal A." seçeneğine göre listele

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    Cutaneous and scalp metastases of pancreatic carcinoma: Case report
    (2011) Küçüköner M.; Kaplan M.A.; Inal A.; Sula B.; Firat U.; Uçmak F.; Işikdoğan A.
    Pancreatic carcinomas are very rapidly progressing tumors. Approximately 50% patients with newly diagnosed pancreatic cancer have many kinds of metastases. The most frequent sites of metastasis of the pancreatic carcinomas are the lymph nodes, lungs, liver, adrenal glands, kidneys and bones. Cutaneous metastases from pancreatic adenocarcinomas are very rare, far less common sites of pancreatic metastases are the scalp and skull metastases. The most common site of cutaneous metastasis is the umbilicus, there are scant reports of pancreatic cutaneous metasta sis at nonumbilical areas. In the literature, togetherness of cutaneous, scalp and skull metastases have not usually been reported and in our interesting case, we present these rare metastases together. Copyright © 2011 by Türkiye Klinikleri.
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    Is lymph node ratio prognostic factor for survival in elderly patients with node positive breast cancer?: The Anatolian society of medical oncology
    (2013) Inal A.; Akman T.; Yaman S.; Ozturk S.C.; Geredeli C.; Bilici M.; Inanc M.
    Several studies have now demonstrated that the lymph node ratio (LNR), as a superior indicator of axillary tumor burden to the number of excised nodes. While, about the prognostic value of LNR on the the survival of elderly patients is limited. The aim of this retrospective multicenter study is to evaluate the prognostic value of lymph node ratio in elderly patients with node positive breast cancer. METHODS: Onehundredeightyfour patient with operable breast cancer, recruited from 17 institutions, were enrolled into the retrospectively study Eleven potential prognostic variables were chosen for analysis in this study Univariate and multivariate analyses were conducted to identify prognostic factors associated with survival. RESULT: Among the eleven variables of univariate analysis, four variables were identified to have prognostic significance for Overall survival (OS): patholo^c tumor size (T), No. oppositive nodes (N), LNR and estrogen receptor-positive (ER). Among the eleven variables of univariate analysis, two variables were identified to have prognostic significance for Disease-free survival (DFS): N and LNR. Multivariate analysis by Cox proportional hazard model showed that T, LNR and ER were considered independent prognostic factors for OS. Furthermore, LNR was considered independent prognostic factors for DFS. CONCLUSION: In conclusion, the LNR was associated with the prognostic importance for DFS and OS in elderly patients who were administered adjuvant treatments.
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    Significance of hormone receptor status in comparison of 18F-FDG-PET/CT and 99mTc-MDP bone scintigraphy for evaluating bone metastases in patients with breast cancer: Single center experience
    (Asian Pacific Organization for Cancer Prevention, 2015) Teke F.; Teke M.; Inal A.; Kaplan M.A.; Kucukoner M.; Aksu R.; Urakci Z.
    Background: Fluorine-18 deoxyglucose positron emission tomography computed tomography (18F-FDG-PET/CT) and bone scintigraphy (BS) are widely used for the detection of bone involvement. The optimal imaging modality for the detection of bone metastases in hormone receptor positive (+) and negative (-) groups of breast cancer remains ambiguous. Materials and Methods: Sixty-two patients with breast cancer, who had undergone both 18F-FDG-PET/CT and BS, being eventually diagnosed as having bone metastases, were enrolled in this study. Results: 18F-FDG-PET/CT had higher sensitivity and specificity than BS. Our data showed that 18F-FDG-PET/CT had a sensitivity of 93.4% and a specificity of 99.4%, whiel for BS they were 84.5%, and 89.6% in the diagnosis of bone metastases. x statistics were calculated for 18F-FDGPET/CT and BS. The x-value was 0.65 between 18F-FDG-PET/CT and BS in all patients. On the other hand, the x-values were 0.70 in the hormone receptor (+) group, and 0.51 in hormone receptor (-) group. The x-values suggested excellent agreement between all patient and hormone receptor (+) groups, while the x-values suggested good agreement in the hormone receptor (-) group. Conclusions: The sensitivity and specificity for 18F-FDG-PET/CT were higher than BS in the screening of metastatic bone lesions in all patients. Similarly 18F-FDG-PET/CT had higher sensitivity and specificity in hormone receptor (+) and (-) groups.