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Öğe The effects of deficiency and exogenous administration of epidermal growth factor in rat(Indian Veterinary Journal, 2006) Ketani, M. A.; Hatipoglu, E. S.Recently it has been shown that the epidermal growth factor (EGF) and its receptors (EGF-R) are expressed in uterus in many mammals, (Tamada et al., 2000). Epidermal growth factor (EGF) is a low molecular weight polypeptide with 53 amino acids and is known to stimulate cell proliferation and differentiation in a wide range of tissue. EGF is thought to have important functions in epithelial growth and differentiation. (Tsutsumi et al., 1986). Substantial evidence has been accumulated suggesting that these growth factors play important role in embryo development and implantation (Paria et al., 1993). The objective of the present study was to determine sialoadenectomy and exogenous EGF administration effects on uterinal EGF-R expression and ultrastructural changes in a rat model.Öğe Micrometry and histology of circumvallate papillae in rat(Indian Veterinary Journal, 2006) Kilinc, M.; Ketani, M. A.; Hatipoglu, E. S.; Tacar, O.The circumvallate papilla of the rat is a horseshoe - shaped, midline structure situated in the posterior of the tongue. A papilla is often surrounded by a circular moat or trench. The purpose of the present study was to investigate micrometric measurements of circumvallate papillae during postnatal development in male and female rats.Öğe Relationship between radiographic features and bone mineral density in elderly men(Via Medica, 2010) Karabulut, Oe; Tuncer, M. C.; Karabulut, Z.; Acikgoz, A.; Hatipoglu, E. S.; Akkus, Z.Lumbar disc degeneration is characterised radiologically by the presence of osteophytes, endplate sclerosis, and disc space narrowing. Our study was designed to assess anterior lumbar osteophytes, disc space narrowing, end plate sclerosis, and bone mineral density (BMD) in the lumbar vertebrae and femoral neck of elderly men. A total of 1000 men, aged between 71 and 90 years, were invited to participate in the study. BMD was assessed at the spine and femoral neck using dual energy X-ray absorptiometry (DXA). We examined the relationship with the degree of lumbar spinal and femoral neck deformity by using the Z-score. Lateral and anterioposterior spinal radiographs were evaluated for features of lumbar disc degeneration. The observers consisted of a consultant physical therapist, a radiologist, and anatomists who together studied the series of radiographs. Anterior lumbar osteophytes (grade 0-3), end-plate sclerosis, and disc space narrowing (grade 0-2) were evaluated. The Pearson correlation test was used to determine the association between radiographic features, the lumbar mineral density (LBMD), and femoral neck mineral density (FNBMD). In all, 90.6% of lumbar vertebral levels showed evidence of anterior osteophytes, 87.5% showed evidence of end plate sclerosis, and 68.2% of disc space narrowing. Additionally, there was a strong negative correlation in terms of age at the femoral neck, though not at the spine. On the other hand, there was a significant correlation between osteophyte grade and end plate sclerosis at the spine. In our study, the radiographic features of lumbar disc degeneration, anterior osteophytes, and end plate sclerosis were associated with an increase in BMD at the spine. (Folia Morphol 2010; 69, 3: 170-176)Öğe The variations of Q angle values with gender in young healthy adults(Medimond S R L, 2007) Karabulut, O.; Hatipoglu, E. S.; Kavak, V.; Kara, I. H.The quadriceps (Q) angle is a clinical measure of the alignment of the quadriceps femoris musculature relative to the underlying skeletal structures of the pelvis, femur and tibia(1). Patellar malalignment, the most important reason for anterior knee pain is commonly determined by the Q angle. In this study we aimed to investigate the Q angle differences in 135 healthy young individuals without any complaints of knee. The mean age of the 75 male participants was 20,2 and of 60 female participants was 19,53. The participants were measured by a goniometer in upright position with a standardized foot position. The measurement points used were the right anterior superior iliac spine, the right tibial tuberosity and the midpoint of right patellae. We reported the Q angle of each participant also the age and body mass index. We used SPSS PC programme for statistical analysis. Independent Samples Test was used for comparements. P < 0,05 was accepted as statistically significant. In conclusion we found significant difference in Q angle values of male and female subjects.
