Yazar "Hakverdi, AU" seçeneğine göre listele

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    Expression of E-cadherin in squamous cell carcinomas of the cervix with correlations to clinicopathological features
    (I R O G Canada, Inc, 2005) Yaldiz, M; Hakverdi, AU; Bayhan, G; Akkus, Z
    Objective: To evaluate the expression of E-cadherin, a calcium-dependent cell adhesion molecule, in a retrospective analysis of paraffin-embedded tissue specimens of cervical squamous carcinoma and the relationship with histopathological differentiation and lymph node status. Methods: In this study, we investigated by immunohistochemistry E-cadherin expression in ten normal cervical epithelia and 24 cervical invasive squamous carcinomas. Results: Normal cervical squamous epithelium showed strong expression of E-cadherin at the membrane of the cell and intercellular junctions. In 24 tumors immunnostained by E-cadherin antibody, 11 (46%) showed preserved expression and 13 (54%) reduced expression. There was no significant correlation between E-cadherin expression and histological differentiation (p = 0.650, p = 0.294). In the status of lymph node metastasis, reduced expression of E-cadherin was seen in 11/15 (73%) with lymph node metastasis versus 2/9 (22%) without lymph node metastasis. There was a significant inverse correlation between E-cadherin expression and lymph node metastasis (p = 0.032). Conclusion: Reduced E-cadherin expression may be an important factor among a variety of biologic events that occur during the process of metastasis. However, this should be explored by a large scale study.
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    Incomplete androgen insensitivity (testicular feminization) syndrome: Two case reports
    (Munksgaard Int Publ Ltd, 1996) Hakverdi, AU; Taner, CE; Aban, M; Vural, A; Gungoren, A; Yilmaz, N
    [Abstract Not Available]
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    Menstrual disorders and pelvic pain after sterilization
    (Kluwer Academic Publ, 1995) Taner, CE; Hakverdi, AU; Erden, AC; Satici, O
    Changes in menstrual cycle length, menstrual duration, number of pads, dysmenorrhea and non-cyclic pelvic pain were studied in 43 women following tubal sterilization with three different techniques. One group consisted of 17 women undergoing laparotomy by Pomeroy technique; the second group consisted of 11 women undergoing laparoscopy by Fallope rings; and the third group consisted of 15 women undergoing colpotomy by fimbriectomy. The differences before and after sterilization in cycle length were non-significant in all groups (p>0.05). After sterilization, menstrual duration and number of pads were significantly increased in the laparotomy (p<0.001) and laparoscopy (p<0.01) groups but non-significantly in the colpotomy group (p>0.05). Comparison of these parameters between the groups did not show any significant differences (p>0.05). After sterilization, increases in the severity of dysmenorrhea and non-cyclic pelvic pain were non-significant in all groups (p>0.05). We concluded that there were no significant differences in menstrual disorders after sterilization among these three different techniques.
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    Prevalence, management and outcome in eclampsia
    (Wiley, 1996) Taner, CE; Hakverdi, AU; Aban, M; Erden, AC; Ozelbaykal, U
    Objective: To review the management of eclampsia in our institution. Method:The prevalence, management and outcome of women with eclampsia over a period of 8 years were reviewed at our referral medical center. There were 444 patients with eclampsia among 5757 deliveries (1 in 12.96 deliveries or 7.71% of deliveries). Most of the cases were uneducated and had received no antenatal care. One hundred eighty-one cases were nulliparous (40.77%). High parities of more than five were observed in 27.93% of cases. A standard magnesium sulfate regimen, similar to Prichard's intramuscular regimen, was used. Results: Magnesium sulfate effectively controlled the convulsions. The incidence of abdominal delivery among 397 cases with ante- and intrapartum eclampsia was 50.12%. Perinatal mortality was very high (591.47%0) for all cases. Maternal complications were serious and led to maternal death in 42 women (9.46%). Conclusion: Eclampsia is still a serious obstetric complication particularly in uneducated women who do not receive antenatal care.