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Öğe Restrictive factors for detection of responsible agent in perioperative anaphylaxis: A case report(Bayrakol Medical Publisher, 2019) Gunes, Haci Yusuf; Guzel, AbdulmenapPerioperative anaphylaxis is a type I hypersensitivity reaction, which rapidly develops with severe and variable clinical findings and can be fatal even in previously healthy patients. Early diagnosis and appropriate treatment are required but identifying the responsible agent is difficult. After anaphylaxis developed in our case, we did not have a healthy and adequate knowledge about the following questions. When should we get the blood sample, how much blood and to which tubes? Which tests can we work for detection of the responsible agent, where and in which laboratories? When we were communicating with the centers and laboratories which are given as references, we could not reach to standard information. Therefore, when perioperative anaphylaxis develops, it would be beneficial to have a set of perioperative anaphylaxis management guideline, including contact information of a national center for feedback and a reference anesthetic allergy testing center that could identify the responsible agent.