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    EFFECTS OF SLEEP QUALITY, INCOME LEVEL AND COMORBID CONDITIONS ON QUALITY OF LIFE IN A TURKISH ELDERLY POPULATION: A MULTICENTRE STUDY
    (Gunes Kitabevi Ltd Sti, 2015) Gunduz, Ercan; Eskin, Fatih; Gunduz, Mehmet; Bentli, Recep; Selcuk, Engin Burak; Zengin, Yilmaz; Icer, Mustafa
    Introduction: Our aim is to investigate the effects of sleep quality, income level and comorbid conditions on Quality of Life in a Turkish elderly population. Materials and Method: This multicentric study was performed in seven districts. A total of 1030 patients older than 65 years of age who applied to the internal medicine and geriatrics outpatient clinics of study centres between January and December 2014 were included. All patients underwent the Pittsburgh Sleep Quality Index and Quality of Life Assessment (Short Form 36) tests viaface to face interview method. The demographic properties of patients were also recorded during this interview. Results: The mean Quality of Life subscale scores, except for vitality, were significantly lower (p < 0.001) in patients with poor sleep quality. When analysing the relationship between Quality of Life and multiple chronic diseases, it was observed that patients having multiple chronic diseases had significantly lowered scores in three subscales (physical functioning, mental health and bodily pain; p=0.04, p=0.04, p=0.01, respectively). There were significant differences between patients with high versus low income level with respect to the mean physical functioning, mental health and bodily pain subscales (p=0.01). Conclusion: Our study demonstrated an adverse effect of low sleep quality, multiple chronic disorders and low income level on Quality of Life.
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    Malnutrition in Community-Dwelling Elderly in Turkey: A Multicenter, Cross-Sectional Study
    (Int Scientific Information, Inc, 2015) Gunduz, Ercan; Eskin, Fatih; Gunduz, Mehmet; Bentli, Recep; Zengin, Yilmaz; Dursun, Recep; Icer, Mustafa
    Background: This study aimed to investigate the prevalence of malnutrition and explore the somatic, psychological, functional, and social or lifestyle characteristics linked to malnutrition in elderly people at a hospital in Turkey. Material/Methods: This study included 1030 patients older than 65 years of age who were seen at the internal medicine and geriatrics outpatient clinics of the study centers in Istanbul, Ankara, Duzce, Corum, Mardin, Malatya, and Diyarbakir provinces between January and December 2014. All patients underwent Mini Nutritional Assessment (MNA) and Geriatric Depression Scale (GDS) tests via one-on-one interview method. The demographic properties of the patients were also recorded during this interview. Results: Among 1030 patients included in this study, 196 (19%) had malnutrition and 300 (29.1%) had malnutrition risk. The malnutrition group and the other groups were significantly different with respect to mean GDS score, income status, educational status, the number of children, functional status (ADL, IADL), the number of patients with depression, and the number of comorbid disorders. According to the results of the logistic regression analysis, age (OR=95% CI: 1.007-1.056; p=0.012), BMI (OR= 95% CI: 0.702-0.796; p<0.001), educational status (OR= 95% CI: 0.359-0.897; p=0.015), comorbidity (OR= 95% CI: 2.296-5.448; p<0.001), and depression score (OR= 95% CI: 1.104-3.051; p=0.02) were independently associated with malnutrition. Conclusions: Our study demonstrates that age, depression, BMI, comorbidity, and the educational status were independently associated with malnutrition in an elderly population.
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    Standard blood parameters in anemic patients with cancer and with other diseases
    (Allied Acad, 2017) Gunduz, Ercan; Durgun, Hasan Mansur; Gunduz, Mehmet; Ozen, Mehmet
    Introduction: In this study, we aimed to retrospectively investigate the relationship of the clinical and hematological parameters with malignancies in patients with anemia. Patients and methods: Between January 2012 and February 2014, 54385 patients admitted to our emergency clinic. Of this population 1047 had anemia and were eligible for inclusion criterion to the study. Hematologic parameters of patients counted in an analyzer device (CELL-DYN 3700, Abbott Diagnostics, Abbott Park, IL, USA). Results: According to the final diagnoses made in the admission clinics, the patients were grouped into malign and benign. One hundred and sixty-six (15.8%) patients were grouped as malign and 881 (84.2%) as benign. Malign group was older and had a greater male percentage than benign group. MPV and sedimentation rate were significantly higher in the malign group. Hemoglobin, hemotocrit, erythrocyte and platelet count were significantly lower in the malign group. In logistic regression analysis the independent predictors of malignancies were MPV (odds ratio (OR)=1.206; 95% confidence interval (CI)=1.050-1.386; p=0.008), age (OR=1.028; 95% CI=1.018-1.037; p<0.001), male gender (OR=1.835; 95% CI=1.197-2.814; p=0.005), and hemotocrit (OR=0.837; 95% CI=0.712-0.962; p=0.004). Conclusion: Our study showed that age, male sex, hematocrit, and MPV were the on the population level statistically significant independent predictors of malignancies in patients diagnosed with anemia in emergency department.
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    Survival in rhino-orbito-cerebral mucormycosis: An international, multicenter ID-IRI study
    (Elsevier, 2022) Cag, Yasemin; Erdem, Hakan; Gunduz, Mehmet; Komur, Suheyla; Ankarali, Handan; Ural, Serap; Tasbakan, Meltem
    Background: Mucormycosis is an emerging aggressive mold infection. This study aimed to assess the outcome of hospitalized adults with rhino-orbito-cerebral mucormycosis (ROCM). The secondary objective was to identify prognostic factors in this setting. Methods: This study was an international, retrospective, multicenter study. Patients' data were collected from 29 referral centers in 6 countries. All qualified as proven cases according to the EORTC/MSGERC criteria. Results: We included 74 consecutive adult patients hospitalized with ROCM. Rhino-orbito-cerebral type infection was the most common presentation (n = 43; 58.1%) followed by rhino-orbital type (n = 31; 41.9%). Twenty (27%) had acquired nosocomial bacterial infections. A total of 59 (79.7%) patients (16 in combination) received appropriate antifungal treatment with high-doses of liposomal amphotericin B. Fifty-six patients (75.7%) underwent curative surgery. Thirty-five (47.3%) required intensive care unit admission (27; 36.5% under mechanical ventilation). Hospital survival was 56.8%, being reduced to 7.4% in patients with invasive mechanical ventilation. A multivariate binary backward logistic regression model identified confusion at admission (OR 11.48), overlapping hospital-acquired infection (OR 10.27), use of antifungal treatment before diagnosis (OR 10.20), no surgical debridement (OR 5.92), and the absence of prior sinusitis (OR 6.32) were independently associated with increased risk for death. Conclusion: Today, ROCM still has high mortality rate. Improving source control, rational therpy, and preventing nosocomial infections may improve survival in this severe infection.