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Öğe Congenital os vomer agenesis: Case report and literature review(Vendome Group Llc, 2012) Yorgancilar, Ediz; Yildirim, Muzeyyen; Gun, Ramazan; Meric, Faruk; Topcu, IsmailDefects of the nasal septum occur as a result of a variety of causes, including tuberculosis, irritation, neoplasia, trauma, infection, and chronic inflammatory diseases. Congenital os vomer agenesis as a cause is very rare. We report the case of a 28-year-old man with a defect in the posteroinferior part of the nasal septum that was discovered incidentally during a routine endoscopic examination. The patient was diagnosed with congenital os vomer agenesis, and the diagnosis was confirmed by computed tomography We discuss the features of this case and review the literature on this rare anomaly.Öğe Deep neck space infections: a retrospective review of 173 cases(W B Saunders Co-Elsevier Inc, 2012) Bakir, Salih; Tanriverdi, M. Halis; Gun, Ramazan; Yorgancilar, A. Ediz; Yildirim, Muzeyyen; Tekbas, Guven; Palanci, YilmazPurpose: The purpose of this study is to review our recent experience with deep neck infections and emphasize the importance of radiologic evaluation and appropriate treatment selection in those patients. Materials and Methods: The records of 173 patients treated for deep neck infection at the Department of Otolaryngology and Head and Neck Surgery of Dicle University Hospital during the period from 2003 to 2010 were retrospectively reviewed. Their demography, symptoms, etiology, seasonal distribution, bacteriology, radiology, site of deep neck infection, durations of the hospital admission and hospital stay, treatment, complications, and outcomes were evaluated. The findings were compared to those in the available literature. Results: Dental infection was the most common cause of deep neck infection (48.6%). Peritonsillar infections (19.7%) and tuberculosis (6.9%) were the other most common cause. Pain, odynophagia, dysphagia, and fever were the most common presenting symptoms. Radiologic evaluation was performed on almost all of the patients (98.3%) to identify the location, extent, and character (cellulitis or abscesses) of the infections. Computed tomography was performed in 85.3% of patients. The most common involved site was the submandibular space (26.1%). In 29.5% of cases, the infection involved more than one space. All the patients were taken to intravenous antibiotic therapy. Surgical intervention was required in 95 patients (59.5%), whereas 78 patients (40.5%) were treated with intravenous antibiotic therapy alone. Life-threatening complications were developed in 13.8% of cases; 170 patients (98.3%) were discharged in stable condition. Conclusion: Despite the wide use of antibiotics, deep neck space infections are commonly seen. Today, complications of deep neck infections are often life threatening. Although surgical drainage remains the main method of treating deep neck abscesses, conservative medical treatment are effective in selective cases. (C) 2012 Elsevier Inc. All rights reserved.Öğe EFFECT OF EXTREMELY LOW FREQUENCY MAGNETIC FIELD AND MOBILE PHONE EXPOSURE ON NASAL MUCOSA AND NOSE SKIN(Diagnosis Press Ltd, 2011) Dasdag, Suleyman; Akdag, Mehmet Zulkuf; Meric, Faruk; Uzunlar, Ali Kemal; Celik, Mustafa Salih; Gun, RamazanThe increasing usage of wireless comunication systems and electric-electronical systems in daily life has caused a concern over possible adverse effects of radio frequency radiation (RFR) and Extremely Low Frequency Magnetic Fields (ELF-MF) on biological systems. The aim of the study was to investigate the long-term effect of 900 MHz RFR and ELF-MF exposure on nasal mucosa and nose skin of rats. In this study two different exposure systems were used to get information about the effects of RFR emitted from mobile phones and ELF-MF on nose. In the first part of the study Twenty one Wistar Albino adult male rats (sham: 7, exposure: 14) were used to determine the effects of 900 MHz RFR on nose. For the exposure group, rat heads were exposed to the 900 MHz RFR 2 h per day (7 days in a week) for 10 months. For the sham group, same process was applied to the rats, except that the generator was turned off In the second part of the study 30 male Sprague-Dawley rats (Mona: 10, first exposure: 10, second exposure: 10) were used to determine the effects of 100 mu T and 500 mu T extremely low frequency magnetic field (ELF-MF) which complies to the safety standards for public and occupational exposure. The rats in the exposure groups of this part of the study were exposed to 100 mu T and 500 mu T ELF-MF for 2 hours per day (7 days in a week) during 10 months in a Plexiglas cage. For the sham group, the same experimental process was applied to the rats but ELF-MF generator was turned off The results of the present study showed that 10 months of exposures of mobile phones and ELF-MF do not affect the mucous membrane and skin of nose. In conclusion, radiofrequency and ELF-MF used in this study do not affect nasal skin and mucosa of rats exposed to 900 MHz RFR, 100 mu T and 500 mu T ELF-MF.Öğe The Effects of Hyperbaric Oxygen Therapy Against Streptomycin Ototoxicity(Derman Medical Publ, 2014) Bakir, Salih; Ozbay, Musa; Kinis, Vefa; Yorgancilar, Ediz; Gun, Ramazan; Gul, Aylin; Alabalik, UlasAim: Hyperbaric oxygen (HBO) is an important adjuvant therapy and being increasingly used in the treatment of various disorders because of having an important antioxidant activity. This experimental study was designed to determine the possible protective effect of HBO therapy on streptomycininduced ototoxicity. Material and Method: Twenty-eight adult Wistar albino rats were divided into four groups: Streptomycin (n= 7), saline (n= 7), HBO (n= 7), and streptomycin plus HBO (n= 7). The HBO administered rats were placed into a large pressure chamber and received 100% oxygene at 2.5 atmosphere absolute for 60 minutes per day in a period of seven days. Rats were tested with DPOAE (Distortion Product Otoacoustic Emissions) in the beginning and the end of study. The animals in all groups were sacrificed under general anesthesia on the seventh day. Biopsy specimens from inner ear were stored for histopathologic examination with hematoxylin and eosin (H& E) under light microscopy. Results: Outer hair cells shown by light microscopic images were mostly preserved in control and HBO group. DPOAE measurements revealed no significant differences between the beginning and the end (p> 0.05). Streptomycin and streptomycin plus HBO treated rats showed loss of hair cells and auditory functions significantly (p< 0.05). Between the groups of streptomycin and streptomycin plus HBO; there was no statistically significance according to the analysis of the histopathological scores and DPgram results (p> 0.05). Discussion: HBO has probably no harmful effect on hair cells. But it seems to be not beneficial in a streptomycin-induced cochlear damage rat model.Öğe EFFECTS OF HYPERBARIC OXYGEN THERAPY ON RAT NASAL MUCOSA(Diagnosis Press Ltd, 2012) Yorgancilar, Ediz; Tunik, Selcuk; Deveci, Engin; Gun, Ramazan; Bakir, Salih; Kinis, Vefa; Ayaz, ErcanThe objective of this study was to evaluate the histopathologic effects of hyperbaric oxygen (HBO) therapy on the rat nasal mucosa. Twelve adult Sprague-Dawley rats, each weighing 180-220 g, were used as experimental animals. The rats were divided into HBO (hyperbaric oxygen) and control group. The rats in the HBO group (n = 6) were placed into a 20-liter HBO chamber (2.5 atmospheres absolute LAW, 25-26 degrees C with 100 % oxygen) for 90 min per day. The rats received hyperbaric oxygen over a period of 7 days. The rats in the control group (n = 6) were not given HBO. All animals were sacrificed at the end of the study, and nasal tissue samples were prepared. The sections were stained with Haematoxylin and Eosin (H-E), Periodic acid-Schiff (PAS) and Trichrome-Masson to observe the under a light microscope. Immunoreactivity of pseudostratified epithelial cells of the nasal mucosa was assessed with E-cadherin expression by immunohistochemical staining. There were significant differences in the average histopathological score between the groups exposed and non-exposed to HBO. In the HBO group, degenerative changes in epithelial cells were observed. The goblet cells showed expansion of their structure. Mononuclear lymphocyte infiltration, dilation of blood vessels, and hemorrhage were observed in considerable areas of connective tissue. In the immunohistochemical evaluation of E-cadherin expression, there were no significant differences between the two groups. Biotechnol. & Biotechnol. Eq. 2012, 26(6), 3394-3396Öğe The Effects of Systemic Use of Nicotine on the Rat Nasal Mucosa: a Histopathologic and Immunohistochemical Study(Soc Chilena Anatomia, 2012) Yorgancilar, Ediz; Tunik, Selcuk; Deveci, Engin; Gun, Ramazan; Bakir, Salih; Kinis, Vefa; Ayaz, ErcanThe objective of this study was to evaluate the histopathologic effects of systemic use of nicotine on the rat nasal mucosa. Twelve adult Sprague-Dawley rats weighing 180-220 g, were used as experimental animals. The rats were divided into Nicotine and control groups. The rats of Nicotine groups (n=6) were administered 2mg/kg Nicotine sulphate for 28 days. The rats of control group (n=6) were only administered 1,5 ml physiologic saline solution subcutaneously for 28 days. All animals were sacrified at the end of the study and nasal tissue samples were removed and prepared for histologic examination. The sections were stained with Hematoxylin and Eosin (H-E) and Periodic acid-Schiff(PAS) and Trichrome-Masson were observed under light microscope. E-cadherin immunreactivity of pseudostrafied epithelial cells of nasal mucosa was assessed by immunohistochemical staining. There were significant differences in average histopathological score between the groups treated and non-treated to nicotine. In nicotine group, degenerative change of epithelial cells and hypertrophy of goblet cells were observed. Leukocytes infiltration was observed in significant areas of connective tissue. E-cadherin expression was significantly decreased in epithelial cells of the nasal mucosa of Nicotine group.Öğe An Evaluation of Preoperative Computed Tomography on Patients with Chronic Otitis Media(Springer, 2012) Yildirim-Baylan, Muzeyyen; Ozmen, Cihan Akgul; Gun, Ramazan; Yorgancilar, Ediz; Akkus, Zeki; Topcu, IsmailThis study aimed to compare the veracity of computed tomography findings on patients undergoing surgery for chronic otitis media (COM) with the surgical findings, and to determine to what extent the preoperative computerized tomography (CT) findings are useful to the surgeon. A series of 56 patients with COM undergoing preoperative CT scanning followed by surgical exploration of the middle ear and mastoid. Operative notes were recorded and data collected on the nature of soft tissue masses, the status of the ossicles, presence or absence of facial canal dehiscence and semicircular canal (SCC) dehiscence and the presence or absence of dural plate erosion, and sigmoid sinus thrombosis. Fifty-six patients were recruited in the study, 30 males and 26 females. The age range was from 16 to 67 years with a mean of 26.51 +/- A 1.4 years. The preoperative CT scan imaging in cases of cholesteatoma, ossicular chain erosion and SCC dehiscence have good correlation with the intraoperative findings. The specificity of preoperative CT scan in detecting facial canal dehiscence, dural plate erosion and sigmoid sinus thrombosis in patient of COM were weak. Preoperative computed tomography evaluation is fairly useful especially in cases of cholesteatoma. According to the results of this study, CT is of value particularly in the definition of cholesteatoma, and in determining ossicular chain erosion and semicircular canal fistula.Öğe HISTOPATHOLOGIC EFFECTS OF GLASS IONOMER BONE CEMENTS APPLICATION TO MAXILLOFACIAL AREA: AN EXPERIMENTAL STUDY IN RABBITS(Diagnosis Press Ltd, 2012) Yorgancilar, Ediz; Firat, Ugur; Gun, Ramazan; Bakir, Salih; Dasdag, Suleyman; Akkus, Zeki; Gokalp, OsmanReconstruction of the maxillofacial bone defects and fractures poses a challenge to the surgeons. Various alternatives and materials have been described for these defects and fractures. Glass ionomer bone cements (GICs) have been used extensively in dentistry but recently they have also been utilized in otolaryngology. We hypothesized that GIC can be an alternative material for maxillofacial reconstruction. However, their biocompatibility is of primary importance because this material will be in direct contact with the tissue for a prolonged tune and might affect it. Therefore the aim of this study was to investigate the tissue responses to GIG in the maxillofacial area in rabbits. The study was carried out on 16 New Zealand White rabbits, which were divided into study (n: 8) and control (n: 8) groups. Experimental defects and fractures were created in the nasal bone, maxilla and zygoma in both the study and the control group. The experimental fractures and defects were reconstructed by GIG in the study group. However, the rabbits in the control group were left to natural healing process. The inflammatory reaction and fibrosis in the rabbits of both the study and the control group were compared by using descriptive histopathological analysis 180 days after application. The tissue reactions were graded. GIG showed a slight inflammatory and fibrous reaction in the rabbit of the study group. Nevertheless, statistical difference between the groups was not observed in terms of inflammatory reaction and fibrosis (P>0.05). The results of this study indicated that GIG is a well tolerated material in maxillofacial reconstruction.Öğe Histopathologic results of long-term sildenafil administration on rat inner ear(W B Saunders Co-Elsevier Inc, 2012) Bakir, Salih; Firat, Ugur; Gun, Ramazan; Bozkurt, Yasar; Yorgancilar, Ediz; Kinis, Vefa; Penbegül, NecmettinObjectives: Sildenafil, a selective inhibitor of phosphodiesterase type 5, is widely used for the treatment of erectile dysfunction. Although cochlear effects of phosphodiesterase type 5 inhibitors remain still unclear because of inadequate data, some evidence that recently emerged indicates that these medications may be responsible for hearing impairment. In the present study, we aimed to examine the histopathologic effects of long-term sildenafil use on the cochlea in a rat model. Methods: The study was performed with adult male Wistar albino rats. The control group was fed on standard laboratory diet. The study group was applied orally with sildenafil therapy, 1.5 mg/kg once a day for 45 days. Rats were anesthetized and decapitated. Each temporal bone was dissected, and the cochleas were removed en bloc. The inner-ear biopsy specimens were examined histologically with hematoxylin and eosin and caspase 3 immunoreaction under light microscopy. Results: Hematoxylin and eosin staining showed no distinctive difference between the control group and the sildenafil group. With immunohistochemical examination, caspase 3 immunoreactivity was observed in the sildenafil group. In the control group, caspase 3 immunoreactivity was not observed. Conclusions: The caspase 3 immunoreactivity in the sildenafil group was strongly associated with an increase in apoptotic events in the cochlea. Long-term use of sildenafil can cause hearing impairment through increased apoptosis. (c) 2012 Elsevier Inc. All rights reserved.Öğe Is there Epithelial Tissue in Bone Pate? A Histopathology Study(Mediterranean Soc Otology & Audiology, 2012) Yorgancilar, Ediz; Firat, Ugur; Alabalik, Ulas; Gun, Ramazan; Yildirim, Muzeyyen; Bakir, Salih; Kinis, VefaObjectives: To evaluate the histology of bone pate collected during mastoidectomy in chronic suppurative otitis media (CSOM) patients with or without cholesteatoma. Study Design: Prospective controlled study. Materials and Methods: The study recruited 32 patients (15 males, 17 females; average age 25.3 (range 19-56 years) who underwent mastoidectomy for CSOM: 16 with cholesteatomas (group I) and 16 controls with granulation or polyp tissue (group II). In all patients, bone pate was collected separately from the mastoid cortex (Level 1), subcortical air cells (Level 2), and just before the antrum mastoideum (Level 3). All samples were stained with hematoxylin-eosin (H&E) and immunochemically with a monoclonal antibody against epithelial membrane antigen (EMA). The presence of squamous epithelium in the bone pate was examined under a light microscope. Results: In Group I, we detected epithelial cells in the bone pate samples obtained from the mastoid subcortex (two of 16 patients) and antrum (four of 16 patients) levels. However, no epithelial cells were observed in bone pate from the mastoid cortex. In the controls (group II), no epithelial tissue was observed in any sample from any level. Conclusions: Epithelial cells can inoculate bone pate collected from the subcortical and antral areas of the mastoid bone in patients with cholesteatomatous CSOM. To prevent epithelial cell inoculation, we recommended that bone pate be collected only from the cortical bone of the mastoid.Öğe LONG-TERM EFFECT OF 900 MHz RADIOFREQUENCY RADIATION EXPOSURE ON COCHLEAR FUNCTIONS(Taylor & Francis Ltd, 2012) Yorgancilar, Ediz; Dasdag, Suleyman; Akdag, Mehmet Zulkuf; Gun, Ramazan; Meric, FarukThe purpose of this study was to investigate the effect of 900 MHz radiofrequency radiation on the cochlear function. Fourteen Wistar albino adult male rats were equally divided into two groups: sham control and exposure groups. Rat heads in the carousel were exposed to 900 MHz microwave radiation (power output: 2 W) emitted from generator The rats in the study group were exposed to the radiofrequency radiation 3 h per day (7 days a week) for 6 months. For the sham group, the same procedure was applied to the rats (3 h per day, 7 days a week for 6 months), except that the generator was turned off Distortion Product Otoacoustic Emissions (DPOAE) values of rats were measured at the beginning of the study (baseline), 3rd and 6th month of the exposure. There were no significant DPOAE changes either in the exposure or sham control groups (P > 0.05). In conclusion, according to the results for the DPOAE values obtained in this study we can state that long-term exposure to 900 MHz radiofrequency radiation, which is 3 h a day (during 6 months), did not affect the cochlear function of rats. However, the DPOAE values obtained in this study do not constitute an example for subjects who talk on the mobile phone for a long time. Biotechnol. & Biotechnol. Eq. 2012, 26(6), 3397-3401Öğe Long-term Follow-up Results of the Patients Suffering from Sudden Hearing Loss(Mediterranean Soc Otology & Audiology, 2013) Akdag, Mehmet; Gul, Aylin; Bakir, Salih; Gun, Ramazan; Ozbay, Musa; Kinis, Vefa; Yorgancilar, EdizObjective: The aim of this follow-up study was to evaluate the time-dependent course of hearing recovery in idiopathic SHL patients. Materials and Methods: Forty-four unilateral idiopathic SHL patients treated with the same standard regimen for 10 days were retrospectively reviewed, then they were invited to return to our hospital for their last visit and last audiogram during the study period. Gender, age, duration and severity of hearing loss, the shape of the audiogram and, the presence of tinnitus were evaluated. Thus, the long-term audiometric data, the final hearing outcome and, the rates of hearing recovery was obtained. Results: There was a significant difference in the degree of hearing loss and the rates of hearing recovery between early stage and long-term follow-up (p<0,001). The most common audiogram shape was flat. Hearing was significantly worse in SHL patients with tinnitus compared to SHL patients without tinnitus (p<0,001). Conclusion: Our results revealed that even if the failure of an initial 10-day course of treatment, a delayed recovery continues and there may still be enough time for complete recovery except profound SHL. Tinnitus on presentation with SHL and profound SHL has been identified as a negative prognostic indicator.Öğe Management of Orbital Complications of Sinusitis in Pediatric Patients(Lippincott Williams & Wilkins, 2013) Kinis, Vefa; Ozbay, Musa; Bakir, Salih; Yorgancilar, Ediz; Gun, Ramazan; Akdag, Mehmet; Sahin, MuhammedThe most common reason of orbital infections is sinusitis. Orbital complications of sinusitis are mostly seen in children. Loss of vision and intracranial infections are among the complications of sinusitis. Prompt diagnosis and treatment is very important in the management of orbital complications. The orbital complication can be in the form of cellulitis or abscess. A retrospective review of 26 pediatric patients with orbital complications due to sinusitis was presented in this study. Of 26 patients, there were 13 cases of preseptal cellulitis, 2 cases of orbital cellulitis, and 11 cases of subperiosteal abscess. We grouped the preseptal and orbital cellulites in one category and the subperiosteal abscess in the other. All patients in the cellulitis group recovered by medical treatment. All the patients were treated by surgical drainage. Early diagnosis and appropriate treatment method are vital for the treatment of orbital complications secondary to sinusitis.Öğe Mental health and quality of life in patients with chronic otitis media(Springer, 2013) Bakir, Salih; Kinis, Vefa; Bez, Yasin; Gun, Ramazan; Yorgancilar, Ediz; Ozbay, Musa; Aguloglu, BulentThe present study focused on the comparison of mental health and quality of life (QoL) between chronic otitis media (COM) patients and the hearing population. The patients with chronic otitis media and healthy control group were enrolled in the study. The duration and severity of the auditory impairment were recorded. In addition to hearing loss (HL), the findings of each patient's other ear disorders (ear discharge and tinnitus) were also recorded. In both the groups, psychological symptom profile and health-related QoL were evaluated and compared using a sociodemographic questionnaire, the Symptom Check List 90-Revised Form (SCL-90-R), and the Short Form-36 (SF-36). According to SCL-90-R, somatization (p < 0.001), interpersonal sensitivity (p < 0.001), depression (p < 0.001), phobic anxiety (p < 0.001), and other subscores, and also global severity index score (p < 0.001) were significantly high in patient group when compared to the control group. The patients with COM reported significantly lower levels of QoL in terms of physical role difficulty (p < 0.001), general health perception (p < 0.004), social functioning (p < 0.001), and mental health (p < 0.017) than those of control subjects. Our results indicated that COM patients with mild or moderate HL have poorer life quality and higher psychological problems. Psychological well being should be also considered in assessment of COM patients in addition to the clinical evaluation and audiological tests.Öğe Outcomes of revision external dacryocystorhinostomy and nasal intubation by bicanalicular silicone tubing under endonasal endoscopic guidance(Ijo Press, 2012) Ari, Seyhmus; Cingu, Abdullah Kursat; Sahin, Alparslan; Gun, Ramazan; Kinis, Vefa; Caca, IhsanAIM: To evaluate the long-term treatment outcomes in patients who underwent revision of external dacryocystorhinostomy (DCR) and nasal intubation by bicanalicular silicone tubing (BSTI) under endonasal endoscopic guidance. METHODS: Data from 28 patients with recurrent dacryocystitis were retrospectively reviewed. Revision external DCR and bicanalicular nasal intubation by silicone tubing under endonasal endoscopic guidance was performed in 28 eyes of 28 patients. The patients were evaluated with respect to the reason of recurrence, time to recurrence, time to revision, duration of follow-up and surgical success. RESULTS: Endoscopic endonasal examination detected an osteotomy-side obstruction by the excessive granulation tissue in 24 patients (86%), nasal septal deviation in three patients (10%) and nasal polyp in one patient (4%). Recurrence occurred after a mean duration of 5.3 +/- 3.7 months following the first operation. The mean time between the first DCR operation and the revision DCR was 11.5 +/- 9.3 months. After a mean follow-up of 14.9 +/- 7.8 months, the rate of anatomic success alone was 85% (24/28); the rate of subjective success was 78% (22/28). CONCLUSION: Revision external DCR and bicanalicular nasal intubation by silicone tubing under endonasal endoscopic guidance can be recommended in patients with recurrent dacryocystitis as a surgical approach that achieves satisfactory objective and subjective success rates.Öğe Predictors of surgical approaches for the repair of anterior cranial base encephaloceles(Springer, 2013) Gun, Ramazan; Tosun, Fuat; Durmaz, Abdullah; Yorgancilar, Ediz; Bakir, Salih; Kamasak, Kaan; Gocmez, CuneytSurgical approaches to the anterior cranial base have changed considerably with the introduction of endonasal endoscopic surgery. This study aims to define the factors which help in selecting the optimal surgical approach for the treatment of anterior cranial base encephaloceles. Patients who received treatment for anterior cranial base encephaloceles at our department between 1996 and 2011 were included in the study. Patients' charts were reviewed retrospectively to collect the necessary data. Treatment periods were classified as before 2000, between 2000 and 2005, and after 2005. The relationship between the treatment period, localization of encephalocele, symptoms related with the lesion, size of skull base defect, and selected treatment modality were investigated. Twenty-five patients, aged between 1 and 61 years with anterior encephaloceles were included in the study. Patients with small asymptomatic frontonasal and trans-ethmoidal encephaloceles (n = 5) were followed without surgery. An external approach with or without subfrontal craniotomy was mainly preferred for resection of sincipital encephaloceles (n = 10), especially with facial deformity. A subfrontal craniotomy approach was used for resection of basal encephaloceles in two cases before 2000. Two cases with sincipital encephaloceles and six cases with basal encephaloceles underwent pure endonasal endoscopic surgery after 2000. Cranial base defects of every size could be repaired using the endoscopic approach. Hydrocephalus and meningitis were the two complications seen after craniotomy in a follow-up period of 13-26 (mean 14.5) months. An external approach with or without craniotomy is needed for encephaloceles with external mass and facial deformity. Otherwise, sincipital and basal encephaloceles can be repaired successfully using the endonasal endoscopic approach.Öğe Prevalence and risk factors of otitis media with effusion in primary school and kindergarten children in provincial and district centers of Diyarbakir(Deomed Publ, Istanbul, 2012) Guzel, Recep; Meric, Faruk; Toprak, Serdar Ferit; Yorgancilar, Argun Ediz; Gun, RamazanObjective: The aim of the present study was to determine the prevalence of otitis media with effusion (OME) among primary school and kindergarten children in provincial and district centers of Diyarbakir. Methods: The study was conducted at 4 primary schools and 3 kindergartens in the city center, and at 13 primary schools in district centers. Using the combined physical examination and otoscopic and tympano-metric evaluations, 256 children out of 1,763 (14.5%) were diagnosed with OME. Results: Among total OME cases (119 girls, 137 boys) 118 (46.1%) had bilateral while 138 cases (53.9%) had unilateral effusion (89 on left and 49 on right ear). The prevalence of OME among primary school students were 12.6% at the city center, 16.3% at district level schools and 15.2% among kindergarten students. Higher OME prevalence is associated with passive smoking and allergic rhinitis. Age, sex, attending kindergarten and socioeconomic status were not significantly related with OME. Conclusion: In conclusion, because of high prevalence of otitis media and its possible severe complications screening equipment should be ensured at primary level health institutions. Screening for OME should be a part of preventive health services particularly for all kindergarten and early elementary school students; and should be performed by ENT specialist or pediatricians/general practitioners trained in pneumatic otoscopic and tympanometric evaluation.Öğe The protective role of caffeic acid phenethyl ester against streptomycin ototoxicity(W B Saunders Co-Elsevier Inc, 2013) Bakir, Salih; Ozbay, Musa; Gun, Ramazan; Yorgancilar, Ediz; Kinis, Vefa; Keles, Aysenur; Abakay, AbdurrahmanObjective: The aim of this experimental study was to investigate the efficacy of caffeic acid phenethyl ester (CAPE) in the prevention of streptomycin-induced ototoxicity. Materials and Methods: Thirty-two adult Wistar albino rats were divided into 4 groups: control (n = 8), streptomycin (n = 8), CAPE (n = 8), and streptomycin + CAPE (n = 8). Rats were tested with distortion product otoacoustic emissions (DPOAEs) before drug administration. The animals in all groups were killed under general anesthesia on the 45th day following last DPOAE measurements. Hearing results were analyzed statistically to determine differences in amplitudes of DPOA E. Also, the cochleas of each rat were evaluated by histopathological and immunohistochemical examination. Results: Significant difference was not observed in cochlear hair cells in the control and CAPE groups. In the streptomycin group, severe degeneration of hair cells and increased apoptotic cells were observed. In the streptomycin + CAPE group, although some deteriorations were observed, hair cells were mostly preserved. The DPgram of the streptomycin and streptomycin + CAPE groups was significantly deteriorated (P < .05). The analysis of the DPgram results revealed statistically significant differences between the groups of streptomycin and streptomycin + CAPE (P < .05). Conclusions: Caffeic acid phenethyl ester treatment attenuated hair cells injury in the inner ear, possibly via its antioxidant effect. Prophylactic administration of CAPE for streptomycin ototoxicity ameliorated hearing deterioration in rats. (C) 2013 Elsevier Inc. All rights reserved.Öğe The relationship between high incidence of deep neck infection and toothbrushing frequency(Academic Journals, 2012) Bakir, Salih; Gunay, Ahmet; Tanriverdi, Halis; Gun, Ramazan; Atilgan, Serhat; Palanci, Yilmaz; Ozbay, MusaThis study aimed to investigate and compare the frequency of toothbrushing and dental health status between deep neck space infection (DNSI) patients with dental origin and healthy population. 64 participants were included in this study in the form of two groups. The first group consisted of 34 DNSI patients with dental onset, and the second group consisted of 30 participants (control group). Study was carried out in two separate categories: the frequency of toothbrushing and assessment of dental health status. Toothbrushing frequency was evaluated with a questionnaire. Dental health status was assessed for periodontal and dental disease by periodontist according to the some widely used indicators; Decayed Missing Filled Teeth (DMFT) scores, Plaque Index score, Gingival Index score and Sulcus Bleeding Index score. Present study showed that the majority had brushed their teeth occasionally. In DNSI group, the percentage of never toothbrushing was very high and regular toothbrushing rate was so low. DNI group has higher scores than the control group and this indicates poor oral hygiene. Our results showed that, oral health was impaired and regular toothbrushing seems to have been neglected in DNSI group. In our opinion, this negligence is a very important contributory factor towards the more occurrence of deep neck abscess.Öğe The relationship between high incidence of deep neck infection and toothbrushing frequency(Academic Journals, 2012) Bakir, Salih; Gunay, Ahmet; Tanriverdi, Halis; Gun, Ramazan; Atilgan, Serhat; Palanci, Yilmaz; Ozbay, MusaThis study aimed to investigate and compare the frequency of toothbrushing and dental health status between Deep neck space infection (DNSI) patients with dental origin and healthy population. 64 participants were included in this study in the form of two groups. The first group consisted of 34 DNSI patients with dental onset, and the second group consisted of 30 participants (control group). Study was carried out in two separate categories: the frequency of toothbrushing and assessment of dental health status. Toothbrushing frequency was evaluated with a questionnaire. Dental health status was assessed for periodontal and dental disease by periodontist according to the some widely used indicators; DMFT scores, Plaque Index score, Gingival Index score and Sulcus Bleeding Index score. Present study showed that the majority had brushed their teeth occasionally. In DNSI group, the percentage of never toothbrushing was very high and regular toothbrushing rate was so low. DNI group has higher scores than the control group and this indicates poor oral hygiene. Our results showed that, oral health was impaired and regular toothbrushing seems to have been neglected in DNSI group. In our opinion, this negligence is a very important contributory factor towards the more occurrence of deep neck abscess.
