Yazar "Gul T." seçeneğine göre listele

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    Distribution of gynecologic malignancies in an epidemiologic study from southeast of Turkey
    (2011) Sakar M.N.; Gul T.; Atay A.E.
    Retrospective evaluation of 105 patients with gynecologic malignancy. One hundred and five patients with gynecologic malignancies diagnosed at Obstetrics and Gynecology Clinics of Medical School, Dicle University, Diyarbakir, between 2001 and 2005 were analyzed retrospectively. Gynecologic malignancies were classified. Distribution of 105 patients with gynecologic malignancies were; cervical cancer 19.04%, endometrial cancer 21.90%, uterine sarcoma 10.47%, primary ovarian cancer 40.95%, metastatic ovarian cancer 5.71%, carcinoma of the fallopian tubes 0.95%, choriocarcinoma 0.95%. 17 of 20 (85%) patients with invasive cervical cancer were in stage?IIa. Endometrioid cancer was the predominant (86.95%) histologic type in 23 patients with endometrial cancer. Leiomyosarcoma was the most frequent (72.72%) histologic type in 11 patients with uterine sarcoma. 33 of 43 patients (76.74%) with ovarian cancer had epithelial type carcinoma. Six patients had metastatic ovarian cancer and 4 patients (66.66%) in this group had Krukenberg tumors (signet-ring cells), 1 patient had primary tubal adenocarcinoma and 1 patient had choriocarcinoma. Ovarian cancer was the most frequent gynecologic malignancy in our study.
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    Internal iliac artery ligation for severe postpartum hemorrhage
    (Via Medica, 2012) Evsen Mehmet S.; Sak M.E.; Soydinc H.E.; Basaranoglu S.; Bakir C.; Sak S.; Gul T.
    Objective: To evaluate the outcomes of bilateral internal iliac artery ligation (IIAL) in severe postpartum hemorrhage (PPH). Design: Multi-center, retrospective study. Methods: The study was performed from January 2005 to December 2010, at the Obstetrics and Gynecology Clinic, Dicle University Medical Faculty and Maternity Hospital, Diyarbakir, Turkey. Life-threatening cases of severe postpartum hemorrhage, which could not be controlled with conservative medical and surgical treatments and finally managed with IIAL, were retrospectively evaluated. Results: Totally 53 patients who underwent IIAL procedures were included in the study. All patients were hemodynamically unstable. The mean shock index and transfused units of blood were 1.17±0.46, 5.49±3.04, respectively. Uterine atony was the leading cause of severe postpartum hemorrhage and the need for IIAL. Coagulopathy developed in 26 (49.1%) patients during the postoperative follow-up period. Uterus was preserved in 17 (32.0%) cases. Three patients died of complications and/or morbidity associated with hemorrhage. Conclusion: Serious PPH is most frequently associated with uterine atony and IIAL should be considered in cases with severe PPH unresponsive to other treatment modalities. If, in the antenatal period, patients have risk factors of postpartum hemorrhage, they must be transferred to appropriate centers to prevent a possibly fatal outcome. © Polskie Towarzys two Ginekologiczne.
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    Omphalocele: Report of two cases
    (2000) Tarlan N.; Demir B.; Gocmen A.; Gul T.
    OMPHALOCELE: REPORT OF TWO CASES Omphalocele is a herniation of the bowel through the umbical ring. It is seen in about 1 in 4000 live births. Omphalocele is often associated with other abnormalities. Chromosomal anomalies particularly trisomies 13,18, 21 are frequently detected. Omphalocele is easy to detect with ultrasound in the early second trimester. Two cases prenatally diagnosed as omphalocele and delivered in our clinic constituted the material of our study. The subject was reviewed in the light of the literature and presented.
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    Serum levels of neopterin, tumor necrosis factor-alpha and Interleukin-6 in preeclampsia: relationship with disease severity.
    (2012) Ozler A.; Turgut A.; Sak M.E.; Evsen M.S.; Soydinc H.E.; Evliyaoglu O.; Gul T.
    There are many studies evaluating the role of inflammation in the pathogenesis of preeclampsia. However, little is known about the relationship between the severity of inflammation and the severity of preeclampsia due to insufficient of studies reporting this matter. To investigate the maternal serum concentrations of IL-6, TNF-alpha and Neopterin in patients with mild preeclampsia and severe preeclampsia and HELLP (hemolysis, elevated liver enzymes, low platelet count) syndrome in preeclampsia and determine their association with the severity of the disease. Patients, hospitalized with the diagnosis of preeclampsia between October 2011 and March 2012, were included in the study. The patients with preeclampsia were divided into three groups as mild preeclampsia, severe preeclampsia and HELLP syndrome. The control group was comprised of normotensive and uncomplicated pregnant women. The serum levels of IL-6, TNF-alpha and Neopterin (NEO) were determined, using enzyme-linked immunosorbent assay. Spearman's rank correlation tests were used for the correlations between the serum levels of inflammatory markers and the severity of preeclampsia. There was no observed significant difference among mean serum TNF-alpha and IL-6 levels of four groups (p > 0.05). The median serum concentration of NEO in subjects with mild preeclampsia of 14.1 nmol/L and severe preeclampsia of 14.8 nmol/L was significantly higher than that of 10.3 nmol/L in normotensive controls (p = 0.013; p = 0.000 respectively). In addition, the median serum concentration of NEO was detected to be highest in subjects with HELLP syndrome. The serum levels of NEO was well correlated with the severity of preeclampsia (r = 0.533, p = 0.000). The serum levels of NEO, an important marker of cellular immunity, associated with severity of disease in patients with preeclampsia.