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    Adult langerhans cell histiocytosis
    (Ortadogu Ad Pres & Publ Co, 2007) Cil, Timucin; Goekalp, Deniz; Tuzcu, Alparslan; Isikdogan, Abdurrahman; Bahceci, Mithat
    Langerhans cell histiocytosis is a group of idiopathic disorders characterized by the abnormal proliferation of specialized bone marrow-derived Langerhans cells. There are one to two cases per million population. Most reports are based only on anecdotal experience in adult patients. Surgical excision, radiotherapy and chemotherapy, either alone or in combination are the main treatment options. In this report, we present a rare case of Langerhans cell histiocytosis in a 32 years-old-woman who developed symptomatic diabetes insipidus and multiple bone and cranial metastases during the disease course. This paper discusses controversial treatment modalities.