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Öğe Effect of a 50-Hz sinusoidal electromagnetic field on the integrity of experimental colonic anastomoses covered with fibrin glue(2009) Girgin S.; Ozturk H.; Gedik E.; Akpolat V.; Kale E.; Ozturk H.Background. Low-frequency magnetic fields have been shown to affect biological In this article the effects of 50-Hz sinusoidal magnetic field (MF) stimulation and application of fibrin glue on the healing of experimental colonic anastomoses were investigated. Material and Methods. Twenty-eight rats were divided into four groups. Group 1 underwent 2-cm left colonic resection and primary anastomosis. Group 2 underwent normal resection anastomosis and the area was covered with fibrin glue. Group 3 underwent normal resection anastomosis and the rats were exposed to a 50-Hz sinusoidal MF. Group 4 underwent normal resection anastomosis, the anastomosis area was covered with fibrin glue, and the rats were exposed to a 50-Hz sinusoidal MF. Investigations included bursting pressure measurement, hydroxypro-line content, and histopathological changes. Results. Tissue hydroxyproline levels and anastomotic bursting pressures of groups 2, 3, and 4 were significantly higher than in group 1. Collagen deposition and fibroblast infiltration in groups 2, 3, and 4 had higher scores than in group 1. Furthermore, these results were significantly higher in group 4 rats than in the other groups. Histopathological examination of the anastomosis revealed significantly better healing patterns for group 4 than for groups 1, 2, and 3. Conclusions. A 50-Hz sinusoidal MF stimulation and application of fibrin glue provided a significant gain in anastomotic healing in the large intestine. A combination of a 50-Hz sinusoidal MF and fibrin glue has significantly favorable effects on healing of experimental colon anastomosis. © Copyright by Wroclaw Medical University.Öğe Etiology, diagnosis and treatment of anal fissure(2007) Girgin S.; Gedik E.; Aldemir M.Anal fissure is a painful ulcer, which is lying longitudinally to dentate line within the anal channel. It is a common illness, which causes morbidity in the healthy population, especially among the young people. Aetiopathogenesis, and the treatment of this illness is contentious, although it was identified long time ago. The treatment of the chronic form of this illness generally requires surgical intervention whereas acute form of the illness responses to medical treatment. Numerous medicines (Botilismus toxin, goniatoxin, glyceril trinitrate, etc), which are aimed to decrease tonus of the internal anal sphincters, which play an important role in the chronic anal fissure's etiopathogenesis and applied surgical methods are currently debatable. In this study we aimed to discuss the diagnostic methods of the anal fissure's aetiopathogenesis, medical, and surgical treatment methods.Öğe Evaluation of surgical methods in patients with blunt liver trauma(2006) Girgin S.; Gedik E.; Taçyildiz I.H.BACKGROUND: We evaluated the surgical methods, morbidity and mortality in patients who had surgery for blunt liver trauma. METHODS: We retrospectively reviewed 159 patients (116 males, 43 females; mean age 33.6; range 15 to 67 years) with blunt hepatic trauma regarding the cause and severity of liver injury, diagnostic procedures, associated injuries, management, morbidity, and mortality. Simple hepatorrhaphy was done in minor liver injuries (Grade I, II). To manage severe liver trauma (Grade III-V), debridement, selective hepatic artery ligation and omentum packing of the laceration (DSO) in 40; resectional debridement (RD) with direct control of bleeding vessels within the liver by the Pringle maneuver in 12; deep matress suture (DMS) in 23; and perihepatic packing (PP) in 9 patients were performed. RESULTS: The causes of trauma were motor vehicle accidents in 102, falls from height in 43 and violence induced blunt trauma in 14 patients. Among 159 patients, 84 had severe liver injuries and 75 had minor liver injuries. Associated organ injuries were present in 104 patients and splenic injury was the most common. Mean units of blood transfusions in DSO, DMS, RD and PP were 4.3, 6.2, 5.5 and 9.5 respectively. Mean time for liver surgery in DSO, RD, DMS and PP were 34.7, 38.1, 26 and 18.2 minutes respectively. Morbidity rate was higher in DMS group than in DSO and RD groups, and the difference was statistically significant (p<0.001). Twenty-five patients (29.4%) died of severe liver injuries and 9 (12%) died of minor liver injuries. The overall mortality rate was 21.3%. CONCLUSION: DSO, and RD methods don't increase operation time and amount of blood transfusion. They cause less morbidity and mortality when compared to DMS.Öğe Quality of life, depression and anxiety among patients who have undergone permanent or temporary ostomy(2008) Yaşan A.; Ünal S.; Gedik E.; Girgin S.Objective: The aim of this study is to compare quality of life, depression and anxiety after ostomy among patients who have undergone permanent or temporary ostomy. Methods: Twenty two patients who were undergone permanent and thirty one patients who were undergone temporary ostomy were included in the study. Sociodemographic and ostomy information form, quality of life scale which had 20 questions and developed for patients with ostomy, the section of SCID-I which was deal with depression and anxiety, Hamilton Depression Rating Scale and State-Trait Anxiety Inventory were applied to those patients. The results determined in the two groups, permanent and temporary ostomy were compared. Results: Depression and anxiety diagnosing rates were 35.85%, and 56.60% among all our patients respectively. Permanent and temporary ostomy groups were compared and a difference was obtained in the answers of these groups to four questions, which was about encountered problem, or anxiety, of quality of life test. On the other hand, any difference was not found in the rates of depression and anxiety. Hamilton Depression Rating Scale and trait anxiety average score were not found between the two groups. But state anxiety average score of temporary ostomy group was obtained higher than permanent ostomy group. Discussion: The presence of ostomy -temporary or permanent- clearly affects the quality of life of patients physically, sociological, and psychologically without regarding temporary or permanent. Also it commonly leading to psychiatric disorders of depression and anxiety. Patients should be routinely screened for these disorders in order to provide early intervention and treatment.
