Yazar "Ertugrul, Sabahattin" seçeneğine göre listele

Listeleniyor 1 - 8 / 8
  • [ X ]
    Öğe
    Attention for fetomaternal and obstetric outcomes of advanced maternal age: a broad range clinical evaluation
    (Derman Medical Publ, 2019) Yilmaz, Ahmet; Yolbas, Ilyas; Yilmaz, Hatice; Bucaktepe, Gamze; Ulucas, Unal; Aktar, Fesih; Ertugrul, Sabahattin
    Aim: Pregnancy >= 35years may lead to different health problems in neonates. The present study was aimed to investigate the effect of pregnancy >= 35 on maternal and infant health. Material and Method: Mothers of the neonates in our neonatal unit were separated into two groups and compared: Group I comprised those between 18 and 35 years old, and Group II comprised those >= 35. Results: Out of 1.193 mothers, 22.1% (264) were above the age of 35 years, whereas 77.8 % (929) were under the age of 35 years. However, there was no significant difference between the groups regarding gender, number of previous delivery, gestational week, the rate of neonatal mortality, polyhydramnios, and oligohydramnios. A statistically significant increase in gestational diabetes, the rate of cesarean delivery and the rate of delivery meconium aspiration syndrome and occurrence of preeclampsia were found in the group for those with advanced age than the other group. Discussion: Much attention should be taken in terms of developing preeclampsia and gestational diabetes in advanced maternal age pregnancies. For a closer follow-up of pregnant women >= 35, establishing relevant units and referral of mother candidates at this age to experienced centers may help to decrease the higher feto-maternal risks for advanced maternal age population.
  • [ X ]
    Öğe
    Determining the Independent Risk Factors and Mortality Rate of Nosocomial Infections in Pediatric Patients
    (Hindawi Ltd, 2016) Aktar, Fesih; Tekin, Recep; Gunes, Ali; Ulgen, Cevat; Tan, Ilhan; Ertugrul, Sabahattin; Kosker, Muhammet
    The objective of this study was to determine the rate, independent risk factors, and outcomes of healthcare-associated infections in pediatric patients. This study was performed between 2011 and 2014 in pediatric clinic and intensive care unit. 86 patients and 86 control subjects were included in the study. Of 86 patients with nosocomial infections (NIs), there were 100 NIs episodes and 90 culture growths. The median age was 32.0 months. The median duration of hospital stay of the patients was 30.0 days. The most frequent pathogens were Coagulase-negative Staphylococcus, Acinetobacter spp., Klebsiella spp., and Candida spp. Unconsciousness, prolonged hospitalization, transfusion, mechanical ventilation, use of central venous catheter, enteral feeding via a nasogastric tube, urinary catheter, and receiving carbapenems and glycopeptides were found to be significantly higher in NIs patients. Multivariate logistic regression analysis showed prolonged hospitalization, neutropenia, and use of central venous catheter and carbapenems as the independent risk factors for NIs. In the univariate analysis, unconsciousness, mechanical ventilation, enteral feeding, use of enteral feeding via a nasogastric tube, H-2 receptor blockers, and port and urinary catheter were significantly associated with mortality. In the multiple logistic regression analysis, only mechanical ventilation was found as an independent predictor of mortality in patients with NIs.
  • [ X ]
    Öğe
    Diagnostic role of inflammatory markers in pediatric Brucella arthritis
    (Bmc, 2016) Aktar, Fesih; Tekin, Recep; Bektas, Mehmet Selcuk; Gunes, Ali; Kosker, Muhammet; Ertugrul, Sabahattin; Yilmaz, Kamil
    Background: As a multisystem infectious disease, there is an inflammation, which causes increase in acute phase reactants in brucellosis. The mean platelet volume (MPV), platelet distribution width (PDW), red cell distribution width (RDW), neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) have been identified as markers of inflammation. The present study aimed to evaluate diagnostic values of these biomarkers in brucella arthritis (BA). Methods: The study included 64 children with BA and 66 healthy control subjects. Demographic features, joint involvement, erythrocyte sedimentation rate (ESR), C-reactive protein (CRP) and hematological variables were retrospectively recorded. In addition, results of synovial fluid and serum tube agglutination test for brucella together with treatment regimens were recorded. Results: The mean age of the patients (53.1 % male) was 92.3 +/- 41.2 months. The most commonly affected joint was ankle (53.1 %). Synovial fluid puncture-brucella agglutination test was positive in 22 (34.3 %) patients. Puncture culture was positive in 9 patients. Most of the patients (57.8 %) were treated with a combination of rifampicin plus sulfamethoxazole/trimethoprim and gentamicin. Significantly higher mean PDW, RDW, MPV, NLR and PLR values were found in children with BA compared to control subjects (p < 0.05). A positive correlation was found between MPV and NLR values (R-2 = 0.192, p < 0.001). Conclusion: Our findings indicated that NLR and PLR are indirect markers of inflammation that may be observed abnormally increased in children with brucella arthritis. Further longitudinal studies are needed to investigate this topic to establish the more clear associations.
  • [ X ]
    Öğe
    Evaluation of urinary tract infections in neonatal indirect hyperbilirubinemia
    (Edizioni Minerva Medica, 2022) Deger, Ibrahim; Ertugrul, Sabahattin; Yolbas, Ilyas; Tekin, Recep
    BACKGROUND: We have evaluated urinary tract infections (UTI) in neonatal indirect hyperbilirubinemia. Urine culture is not routinely requested in patients with indirect hyperbilirubinemia. However, debates continue about the frequency and investigation of UTI in neonatal indirect hyperbilirubinemia patients. The aim of this study was to determine the prevalence of UTI in neonates admitted to the hospital due to pathological indirect hyperbilirubinemia and whether a routine urine culture test is necessary in patients. METHODS: In this retrospective study, we analyzed data from 1390 patients hospitalized to the Neonatal Unit due to pathological indirect hyperbilirubinemia. One hundred and eleven of these patients with detected bacterial agents in the urine cultures were evaluated. The type of the pathogens grown in urine culture, the number of colonies, and the antibiotic resistance status were evaluated. RESULTS: Among 1390 patients screened, 111 (8%) were found to have UTI, 68 of whom (61.3%) were male. Out of the microorganisms that grew, Escherichia coli was the dominant microorganism with 36.1%, which was followed by Klebsiella species (23.4%), and Enterococcus species (18%), respectively. CONCLUSIONS: The prevalence of UTI is high in the neonatal period as in all childhood and especially in patients admitted to the Neonatal Unit due to indirect hyperbilirubinemia. Escherichia coli and Klebsiella species are the most common bacterial agents that grow. Missing the diagnosis of urinary tract infection in neonates may cause renal problems. Therefore, we recommend requesting a urine culture in routine examinations of neonates who are diagnosed with pathological indirect hyperbilirubinemia and admitted to the hospital due to the need for phototherapy.
  • [ X ]
    Öğe
    Mediastinal Gastroenteric Cyst in a Neonate
    (Galenos Yayincilik, 2016) Ipek, Mehmet Sah; Ertugrul, Sabahattin; Ulku, Refik
    Mediastinal cysts in neonates are infrequently reported. Enteric cysts in the posterior mediastinum are mostly asymptomatic. Vertebral malformations may contribute. Clinical presentation may include respiratory distress. Herein, we report a case of mediastinal gastroenteric cyst and meningomyelocele in a neonate presented respiratory distress signs after delivery. The patient was well managed by excision of mediastinal cyst and closure of dura mater of meningomyelocele. A detailed antenatal scan may help in early diagnosis and better outcome. Moreover, vertebral anomaly in chest radiograph of infants with respiratory distress should suggest the possible presence of a mediastinal enteric cyst.
  • [ X ]
    Öğe
    PLASMA TOTAL HOMOCYSTEINE, LIPOPROTEIN (A) AND VON WILLEBRAND FACTOR LEVELS IN ASSESSMENT OF METABOLIC CONTROLS OF CHILDREN WITH TYPE I DIABETES MELLITUS
    (Nobel Ilac, 2014) Ertugrul, Sabahattin; Sen, Yasar; Yilmaz, Erdal; Aydin, Mustafa; Ustundag, Bilal
    Objective: Diabetes is a significant risk factor for early onset of atherosclerosis. In this study, it was aimed to determine whether total homocysteine (tHcy), lipoprotein(a) [Lp(a)] and von Willebrand factor (vWF) levels have an early predictive value like glycolysated hemoglobin (HbA1c) levels in assessment of metabolic condition of children with type I diabetes. Material and Method: Study group consisted of 65 children and adolescents who had type I diabetes but not clinical findings of microvascular and macrovascular complications and 20 healthy children and adolecents with the same age group and gender Blood samples were obtained from diabetic patients, treatments were arranged and patients were followed up (Group I diabetic patients). Patients were re-evaluated at the end of 1 year and blood samples were obtained again (Group H diabetic patients). Results: A statistically significant difference was found between the first (11.1 +/- 3.3 mu mol/L) and the second tHcy levels (10.2 +/- 1.7 mu mol/L) of diabetic patients and tHcy levels of control group (8.9 +/- 2 mu mol/L)(p<0.05 and <0.01, respectively). A statistically significant difference was found between the first (10.4 +/- 5.4 mg/dl) and the second Lp(a) levels (9.0 +/- 4.3 mg/dl) of diabetic patients and Lp(a) levels of control group (5.3 +/- 2.8 mg/dl)(p<0.01 and <0.001, respectively). A statistically significant difference was not found when vWF levels of diabetic groups I and II and control group were compared (p>0.05). A statistically significant positive correlation was found between tHcy and HbA1c, microalbumin in Group I diabetic patients (r=0,389, p=0,02; r=0,286, p=0,034, respectively). A statistically significant positive correlation was found between HbA1c and homocysteine, vWF, microalbumin (r=0,428, p=0,001; r=0,328, p=0,024; r=0,742, p=0,001, respectively) and vWF and microalbumin levels (r=0,560, p=0,001) in Group II diabetic patients. Conclusion: In conclusion, that tHcy and Lp(a) could be beneficial for assessment of metabolic control of diabetes, treatments toward reducing the complications of diabetes or the outcomes of additions to diet.
  • [ X ]
    Öğe
    Recurrent rhabdomyolysis in a child. Case presentation
    (Soc Argentina Pediatria, 2016) Ertugrul, Sabahattin; Yolbas, Ilyas; Aktar, Fesih; Yilmaz, Kamil; Tekin, Recep
    Viral myositis associated with infections rarely may cause rhabdomyolysis. There is no any pediatric case with severe recurrent rhabdomyolysis triggered by infections in the literature. We reported a two-year-old boy who was hospitalized three times due to severe rhabdomyolysis associated with viral myositis in the winter months. This is the first child case presentation with severe rhabdomyolysis triggered by infections. Prednisolone and intravenous immunoglobulin treatments were ineffective in this case.
  • [ X ]
    Öğe
    Risk Factors for Health Care-Associated Bloodstream Infections in a Neonatal Intensive Care Unit
    (Kowsar Corp, 2016) Ertugrul, Sabahattin; Aktar, Fesih; Yolbas, Ilyas; Yilmaz, Ahmet; Elbey, Bilal; Yildirim, Ahmet; Yilmaz, Kamil
    Background: Healthcare-associated bloodstream infections (HCA-BSI) are a major cause of morbidity and mortality in neonatal intensive care units (NICUs). Objectives: We aimed to determine the causative organisms and risk factors of HCA-BSIs in NICUs. Methods: This study was performed between January 2011 and December 2014 in the neonatal intensive care unit of Dicle university, Turkey. The study consisted of 126 patients (infected group) with positive blood culture and 126 randomly selected patients (uninfected control group) with negative blood culture after four days of hospitalization. Results: We found that the most common causative agents isolated from nosocomial infections (NIs) were 20.7% Staphylococcus epidermidis, 26.7% Klebsiella spp., and 13.3% Acinetobacter spp. Incidences of low gestational age, low birth weight, vaginal birth type, and long length of hospitalization were higher in the infected neonates than in the uninfected neonates. In the univariate analysis, surgical operation, ventriculoperitoneal shunt, use of umbilical catheter, nasogastric or orogastric tube, urinary catheter, mechanical ventilation, surfactant treatment, erythrocyte transfusion, plasma transfusion, thrombocyte transfusion, total parenteral nutrition infusion, intracranial hemorrhage, length of hospital stay, fifth-minute Apgar score, and total parenteral nutrition time were significantly associated with NIs. In the multiple logistic regression analysis, fifth-minute Apgar, use of erythrocyte transfusion and surgical operation were found as the independent risk factors for HCA-BSI. Conclusions: This study determined the causative organisms and risk factors of HCA-BSIs in NICUs.