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Öğe Effects of Sildenafil on Dental Tissue(Medwell Online, 2011) Yaman, Ferhan; Soker, Sevda; Atilgan, Serhat; Erol, Behcet; Alp, Harun; Agacayak, Serkan Kamil; Gunay, AhmetTo investigate the effects of Sildenafil on dental tissue. The study was performed with adult female Wistar-Albino rats. Control group (n = 7) were fed on standard laboratory diet until surgery. The study group (n = 7) were administered Sildenafil orally with orogastric tube 10 mg kg(-1) once a day for 30 days. Each rat was anesthetized and mandibular bone with incisor teeth and soft tissue were removed. Dental pulp, dentin, periodental ligament, periodental soft tissue and bone were examined histologically. Neovascularization on the dental pulp and gingiva were significantly higher in the study group. Sildenafil can be used as a supporting factor in dental tissue healing.Öğe Effects of Systemic Zoledronic Acid Administration on Osseointegration of Hydroxyapatite-Coated and Resorbable Blast Material Surface Implants in Rabbit Models(Quintessence Publishing Co Inc, 2012) Yaman, Ferhan; Agacayak, Serkan; Atilgan, Serhat; Benlidayi, Emre; Ucan, Musa Can; Erol, Behcet; Kaya, BeyzaPurpose: It is unknown whether zoledronic acid (ZA) interferes with initial bone healing at implant sites. The goal of this study was to examine the effects of systemic zoledronic acid administration on osseintegration of hydroxyapatite (HA)-coated and resorbable blast material surface (RBM) implants in rabbit models. Materials and Methods: Twenty-eight male New Zealand rabbits (aged 6 to 12 months) were used in this study. Rabbits were randomly assigned to four groups. In group A, HA-coated implants were placed in the right tibia of seven rabbits. In group B, RBM-surface implants were placed in the right tibia of seven rabbits. In group C, HA-coated implants were placed in seven rabbits with intravenous (IV) administration of ZA. Finally, in group D. ROM-surface implants were placed in seven rabbits with IV administration of ZA. For groups C and D, IV zoledronic acid (0.1 mg/kg) was performed monthly during the entire osseointegration period. All of the rabbits were sacrificed 12 weeks after the implantation, and tibial specimens were harvested. Histomorphometric bone-to-implant contact (BIC) analysis and the data were statistically analyzed. Results: The highest BIC percentage was detected in group D, with a mean value of 56.73% +/- 1.85%, as compared with 45.80% +/- 3.77% in group C, 35.11% +/- 0.76% in group B, and 3114% +/- 1.04% in group A. Conclusions: Histomorphometric analyses showed significant improvement in the osseointegration of implants in the RBM-surface ZA group compared with the HA-coated ZA group. The results of this study suggest that systemic ZA administration may improve osseointegration of titanium implants in bone. INT J ORAL MAXILLOFAC IMPLANTS 2012;27:1443-1447Öğe Evaluation of Mandibular Fractures in Children during Five years' in a Dental School(Drunpp-Sarajevo, 2012) Yaman, Ferhan; Atilgan, Serhat; Erol, Behcet; Ucan, Musa Can; Yilmaz, Utku Nezih; Agacayak, Serkan Kamil; Gunes, NedimMandibular fractures are rarely encountered among the pediatric population, and when they do present, their clinical features differ from those in adults. This retrospective study looked at the age, sex, type and cause of fracture, treatment method and associated injuries and complications in 260 cases of mandibular fracture in children under age 16. Among the most significant findings: Fracture incidence had a 3:5 male:female ratio; 52% of all mandibular fractures involved condyle/subcondyle fractures and 50.7% involved symphysis/parasymphysis fractures; the most common treatment method was intermaxillary fixation; in no cases were severe complications observed during the healing period.Öğe Gnathic osteosarcomas, experience of four institutions from Turkey(E-Century Publishing Corp, 2014) Yildiz, Fetin R.; Avci, Arzu; Dereci, Omur; Erol, Behcet; Celasun, Bulent; Gunhan, OmerOsteosarcoma is the most frequent primary gnathic sarcoma. Neither the etiology nor the variables effecting the prognosis are fully known due mostly to the rarity of gnathic osteosarcomas. To date a considerable number of clinicopathologic features have been suggested in the evaluation of gnathic osteosarcomas. Still there is a need to experience on several aspects of management. The aim of this study is to report a series of 33 cases of osteosarcoma involving either mandible or maxilla. The clinical, radiological and histopathological features of our cases have usually been non-specific and the most frequent provisional diagnosis were benign fibroosseous lesion, abnormal mass, giant cell granuloma and benign bone tumor. This non-specific presentation of osteosarcomas of the jaws is compatible with those reported previously. A combined clinical, radiological and pathological study is essential in arriving at the correct diagnosis.Öğe Mandibular fractures: a comparative analysis between young and adult patients in the southeast region of Turkey(Univ Sao Paulo Fac Odontologia Bauru, 2010) Atilgan, Serhat; Erol, Behcet; Yaman, Ferhan; Yilmaz, Nezih; Ucan, Musa CanObjective: The purpose of this study was to review and compare the differences between mandibular fractures in young and adult patients. Material and Methods: Patients treated at the Oral and Maxillofacial Department of Dicle University during a five-year period between 2000 and 2005 were retrospectively evaluated with respect to age groups, gender, etiology, localization and type of fractures, treatment methods and complications. Result: 532 patients were included in the study, 370 (70%) males and 162 (30%) females, with a total of 744 mandibular fractures. The mean age of young patients was 10, with a male-female ratio of 2:1. The mean age of adult patients was 28, with a male-female ratio of 3: 1. The most common causes of injury were falls (65%) in young patients and traffic accidents (38%) in adults. The most common fracture sites were the symphysis (35%) and condyle (36%) in young patients, and the symphysis in adults (36%). Mandibular fractures were generally treated by arch bar and maxillomandibular fixation in both young (67%) and adult (39%) patients, and 43% of the adult patients were treated by open reduction and internal fixation. Conclusion: There was a similar gender, monthly and type of treatment distribution in both young and adult patients in the southeast region of Turkey. However, there were differences regarding age, etiology and fracture site. These findings between young and adult patients are broadly similar to those from other studies. Analysis of small differences may be an important factor in assessing educational and socioeconomic environments.Öğe Maxillar adenocystic carcinomas and surgical-prosthetic rehabilitation(Int Scientific Literature, Inc, 2011) Erol, Behcet; Atilgan, Serahim Serhat; Yaman, Ferhan; Ucan, Musa Can; Yilmaz, Utku Nezih; Yildiz, FetinBackground: Due to its microscopic appearance, characteristic clinical behavior, high level of recurrence and systemic spread, adenocystic carcinoma is considered as separate from other forms of glandular neoplasm. In terms of clinical behavior, it is the most deceptive tumor in the head-neck region. It most commonly involves the parotid, submandibular gland, tongue and accessory salivary glands in the palate. The clinical appearance is of a mass with hardness at palpitation and sometimes pain or sensitivity. Postoperative prosthetic defect rehabilitation is functionally and phonetically essential. Case Report: The first patient was a 50-year-old woman with a painful swelling in the right maxillary molar and palatal region, which had persisted for the previous year and grown rapidly during the previous 2 months, and with congestion in the right side of the nose. The second patient was a 36-year-old woman complaining of swelling in the left cheek 1.5 years previously and an inability to open her mouth 5-6 months before application to our clinic, a solid mass, painful on palpitation, causing facial asymmetry along the left cheek and limiting mouth opening. Conclusions: Our aim is to present and discuss surgical approaches adopted in cases reported as adenocystic carcinoma, which occupies a special place among malign salivary gland tumors, the first case involving the maxillary dentoalveolar structure and maxillary sinus, and the second case involving the buccal, retromaxillary, infratemporal and pterygomandibular fossa.Öğe Melanotic neuroectodermal tumor of infancy(Int Scientific Information, Inc, 2011) Atilgan, Serhat; Erol, Behcet; Yaman, Ferhan; Yilmaz, Utku Nezih; Can, CevatBackground: Melanotic neuroectodermal tumor of infancy (MNTI) is a rare, distinctive neoplasm of neural crest origin, primarily containing melanin, and affecting the maxilla of infants during the first year of life. The tumor is benign but may grow very rapidly and invade the bone marrow. Very rare examples of malignant transformation have also been reported. Treatment consists of surgical removal, somewhat more aggressive than the typical conservative removal. Case Report: A 4-month-old male was admitted to our clinic after the parents noted a rapidly growing swelling in the anterior maxilla 3 weeks previously and difficulty in oral feeding and weight loss due to malnutrition. Conclusions: This tumor is an uncommon benign tumor of neural crest origin occurring in infants. The lesion exhibits a good response to surgical excision, with few recurrences, although long-term follow-up is advised because of the possibility, albeit rare, of malignant change.Öğe Myiasis Caused by Musca domestica Larvae in a Child: A Case Study(Medwell Online, 2011) Ucan, Musa Can; Erol, Behcet; Balacan, Fatma; Atilgan, Serhat; Yaman, Ferhan; Arslanoglu, Zeki; Agacayak, Serkan KamilThe term myiasis is the infestation of tissue by the larvae of flies. This parasitic infestation is well documented in the skin, especially among animals and people in tropical and subtropical zones. Among the sites of infestation, the human mouth is a common site mainly in tropical countries and is associated with inadequate public and personal hygiene. Due to its destructive potential, appropriate treatment is necessary. This study describes oral myiasis in an 8 years old boy who lives relatively warmer area of his country. The myiasis occurred in the anterior upper jaw associated with palatal area of left incisor and lateral tooth. Pathologic soft tissue sockets were observed in the palatal area at the level of the both deciduous incisor and lateral along the deep periodontal tissues.Öğe Total Relaxivities of Material Content in Various Cysts and Ameloblastoma: Implications for Discriminating Different Fluids(Humana Press Inc, 2010) Yilmaz, Utku Nezih; Guner, Rezzan; Erol, BehcetNuclear magnetic resonance T (1) and T (2) relaxivities (r (1) and r (2)) exhibit efficiency of a material to alter the relaxation rates (1/T (1) and 1/T (2)), and they are being used for diagnostic purposes. The determination of total relaxivities (r (1t) and r (2t)) of cystic fluid content and ameloblastoma may therefore be useful for discriminative purposes. In order to determine what makes total relaxivities of hemorrhagic cysts, four sets of tubes containing pooled cyst were doped with increasing concentrations of iron, copper, albumin, and gamma-globulins. These sets were replaced in a phantom together with six individual cysts and one ameloblastoma. The relaxation times were measured by magnetic resonance imaging operating at 1.5 T. The relaxivities of individual ions and proteins were determined from the slope of the relation between relaxation rates and concentration, while total relaxivities were determined by using the increases in relaxation rates and material content of cystic fluid (MC). Iron, copper, albumin, and gamma-globulins were found to be the sources of r (1t) and r (2t). Each of r (1t), r (2t), r (1t)MC, r (2t)MC, and r (2t)/r (1t) are distinctive parameters for each cystic category and ameloblastoma. Except for MC, the parameters measured for ameloblastoma are significantly smaller than those of cysts. The similarity of the present results to those used in clinical applications suggests that each of r (1t), r (2t), r (1t)MC, r (2t)MC, and r (2t)/r (1t) has an ability to discriminate various fluids and masses. The present work also suggests that r (1t)MC, r (2t)MC, and r (2t)/r (1t) can be determined in vivo.