Yazar "Erdem E." seçeneğine göre listele

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    Human placental macrophages (Hofbauer cells) in severe preeclampsia complicated by HELLP syndrome
    (2013) Evsen M.S.; Kalkanli S.; Deveci E.; Sak M.E.; Ozler A.; Baran O.; Erdem E.
    OBJECTIVE: To evaluate Hofbauer cells in the placentas of women diagnosed with HELLP syndrome. STUDY DESIGN: The present study compared 20 patients with HELLP syndrome and 20 control patients with respect to demographics, hematological parameters and the presence of Hofbauer cells in placental samples. CD-68 antibody was used for immunohistochemical examination. The total number and size of Hofbauer cells were measured in the placental villi, and the proportion of Hofbauer cells relative to the vascular structure was also compared between groups. RESULT: The patient and control groups were similar according to baseline obstetric characteristics. White blood cell counts in patients with HELLP syndrome and the control group were 15,139 ± 4,169 and 10,806 ± 2,888, respectively, and were significantly increased among patients with HELLP syndrome (p<0.001). Hofbauer cell numbers in the placental villi of patients with HELLP syndrome were significantly elevated in comparison to normotensive controls (p=0.046). The proportion of Hofbauer cells in the placental villi according to proximity to the vascular structure were 3.85±1.66 in the HELLP group and 1.75±1.12 in controls (p<0.001). Sizes of the Hofbauer cells were not statistically different between groups. CONCLUSION: Increased Hofbauer cells may be associated with increased inflammation or may have an adaptive mechanism at the fetal site of the placenta in patients with HELLP syndrome. (Anal Quant Cytopathol Histopathol 2013;35:283-288). © Science Printers and Publishers, Inc.
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    Production of PbO thin film using Silar method and electronıc and interface properties of Pb/PbO/p-Si MIS contacts
    (S.C. Virtual Company of Phisics S.R.L, 2022) Erdem E.; Asubay S.; Gullu O.
    In this paper, using SILAR thin film technique, which is low cost and is easy to control, the lead oxide (PbO) thin film was grown onto both microscope glass and inorganic semiconductor silicon (Si) wafer after appropriate chemical cleaning processes. The coating stage was performed by keeping the solution at 80 ?. After forming a PbO thin film on the silicon semiconductor, Pb metal was evaporated onto its upper surface. Optical, morphological and structural properties of the PbO thin film formed on glass were investigated. The electrical and interface characteristics of the Pb/PbO/p-Si MIS Schottky diode were investigated in the dark by using current-voltage (I-V), capacity-voltage (C-V) and conductance-voltage (G-V) in 10kHz-2MHz frequency range and capacity-frequency (C-f) characteristics in 1kHz-10MHz frequency range. © 2022, S.C. Virtual Company of Phisics S.R.L. All rights reserved.
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    Synbiotic therapy increases eradication rate in Helicobacter pylori eradication
    (Acta Medica Mediterranea, 2013) Şahin Ö.; Yeşil A.; Şenateş E.; Akdoğan M.F.; Konür S.; Erdem E.; Dal M.S.
    Background: Probiotics are used in combinations of H. pylori eradication regimens with variable results. Many strains tested had shown positive effects on side effect profiles. However, a clear effect on eradication rate is studied thoroughly. We aimed to investigate the beneficial effect of a synbiotic combination in clarithromycin-based triple eradication therapy. Methods: Ninety-two patients who were infected with H. pylori (confirmed via endoscopic biopsy) were randomized into two groups: those undergoing standard triple treatment (control group (rabeprozol plus amoksisilin plus clarithromycin bid) n=49) and those receiving symbiotic (triple plus symbiotic bid group n=43). The symbiotic product contained lactobacillus, bifidobacterium and enterococcus. The 13C-breath test was performed at least 6 weeks after completing both therapy regimens. Results: In the synbiotic group, 3 of the patients complained of metallic taste (7.0%), 1 complained of diarrhea (2.3%), 3 had nausea (7.0%), 2 had gas (4.7%), 3 experienced vomiting (7.0%) and 1 had constipation (2.3%). In the control group, 3 of the patients experienced a metallic taste (6.3%), 7 had diarrhea (14.6%), 5 had nausea (10.4%), 3 had intestinal bloating (6.3%), 3 experienced vomiting (6.3%) and 1 had constipation (2.1%). There was no significant difference between the two groups. However, side effect intensity and eradication rates were significant different between the groups (p<0.05). The eradication rate in the synbiotic group was 88.4%, while it was 68.8% in the control group (p<0.05). Conclusion: The addition of synbiotic to triple therapy decreases the rate of antibiotic-related side effects. It also increases H. pylori eradication rates in clarithromycin-based triple therapy.