Yazar "Ercan, S." seçeneğine göre listele

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    Cardiac Metastasis of A Low-Grade Myofibroblastic Sarcoma
    (Excerpta Medica Inc-Elsevier Science Inc, 2014) Oylumlu, M.; Yildiz, A.; Ercan, S.; Oylumlu, M.; Davutoglu, V.
    [Abstract Not Available]
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    Circadian variation of blood Pressure is impaired in normotensive pregnant women with gestational diabetes mellitus
    (Oxford Univ Press, 2012) Soydinc, E.; Davutoglu, V.; Sak, E.; Evsen, S.; Kaya, H.; Ercan, S.; Sari, I.
    [Abstract Not Available]
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    The effect of bevacizumab and 5-Fluorouracil combination on epidural fibrosis in a rat laminectomy model
    (Verduci Publisher, 2014) Ozkan, U.; Osun, A.; Samancioglu, A.; Ercan, S.; Firat, U.; Kemaloglu, S.
    OBJECTIVE: An animal model of laminectomy in rats was used to study scar tissue formation around the spinal cord. Bevacizumab (BV) [a recombinant, humanized, monoclonal antibody targeting vascular endothelial growth factor], 5-Fluorouracil (5-FU) and BV+5-FU was tested in this system for its ability to decrease fibrous tissue formation. MATERIALS AND METHODS: Twenty-eight Sprague Dawley rats were used in this sudy. Rats were divided into four groups; a control group, a BV group, a 5-FU group and a BV+5-FU group. L12 laminectomies were performed on the rats. The medicated groups were treated with topical drug administration. After 6 weeks, the rats were sacrified and histologic sections prepared from the spines were examined and graded by a pathologist. Epidural fibrosis and fibroblast density were evaluated under light microscope. RESULTS: BV (Avastin: Genentech, San Francisco, CA, USA) significantly reduced the density of the scar tissue undermining the laminas (p < 0.005). Monotherapy with 5-FU did not change the scar formation in the back (p = 0.317). Combination of 5-FU and BV was more effective on reducing the epidural fibrosis after laminectomy on rats (p < 0.001). CONCLUSIONS: Bevacizumab reduced the spinal epidural fibrosis significantly that developed in rats after laminectomy and 5-Fluorouracil combination had a synergic effect. Further investigations under the light of these findings may help to reduce epidural fibrosis formation after laminectomy.
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    The effect of the glucose-insulin-potassium solution on the p-wave dispersion of the heart failure patients
    (Wiley-Blackwell, 2013) Ercan, S.; Oylumlu, M.; Oylumlu, M.; Soydinc, S.; Davutoglu, V.
    [Abstract Not Available]
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    FRAGMENTED QRS IS PREDICTIVE OF MYOCARDIAL DYSFUNCTION, PULMONARY HYPERTENSION AND SEVERITY IN MITRAL STENOSIS
    (Elsevier Ireland Ltd, 2011) Yuce, M.; Davutoglu, V.; Ozbala, B.; Ercan, S.; Kizilkan, N.; Akcay, M.; Sari, I.
    [Abstract Not Available]
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    Öğe
    Increased epicardial fat thickness is related with body mass index in women with polycystic ovary syndrome
    (Verduci Publisher, 2013) Soydinc, E.; Soydinc, S.; Ariturk, Z.; Tekbas, E.; Cakici, M.; Islamoglu, Y.; Ercan, S.
    AIM: We aimed to investigate the relationship between PCOS and epicardial fat thickness with transthoracic echocardiography. PATIENTS AND METHODS: PCOS patients were divided into two groups according to the lean or obesity status: PCOS patients with lean 34 subjects (BMI: 23.3+/-2.8; mean age: 25.5+/-4), PCOS patients with obese16 subjects (BMI: 32.3+/-7.6; mean age: 27.2+/-3.7) were compared with control healthy lean subjects (BMI: 23.5+/-1.7; mean age: 25.9+/-2.2). RESULTS: There was increased epicardial thickness in obese PCOS subjects compared to lean PCOS subjects (6.3+/-0.9 mm, 4.7+/-0.5, respectively, p < 0.001). However, epicardial fat thickness between lean PCOS subjects and lean healthy control groups were not significantly varied (4.7+/-0.5 mm, 4.5+/-0.5, respectively, p = 0.6). There was increased epicardial thickness in obese PCOS subjects compared to lean healthy control subjects (6.3+/-0.9 mm, 4.5+/-0.5, respectively, p < 0.001). This sudy showed for the first time that increased epicardial fat thickness measured using transthoracic echocardiography is associated with increased BMI in PCOS subjects. CONCLUSIONS: Epicardial fat thickness between lean PCOS subjects and lean healty control group were similar which indicate the importance of obesity in PCOS subjects.