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Öğe THE ASSESMENT OF LONG TERM OUTCOMES IN HBSAG NEGATIVE RENAL TRANSPLANT RECIPIENTS WHO WERE TRANSPLANTED FROM HBSAG POSITIVE DONORS(Wiley-Blackwell, 2015) Yilmaz, Vural Taner; Ulger, Burak Veli; Aliosmanoglu, Ibrahim; Erbis, Halil; Tuna, Yasar; Akbas, Halide; Ozdem, Sebahat[Abstract Not Available]Öğe Assessment of Long-Term Outcomes in Hbs Ag-Negative Renal Transplant Recipients Transplanted from Hbs Ag-Positive Donors(Int Scientific Information, Inc, 2015) Yilmaz, Vural Taner; Ulger, Burak Veli; Aliosmanoglu, Ibrahim; Erbis, Halil; Tuna, Yasar; Akbas, Halide; Ozdem, SebahatBackground: The aim of this study was to evaluate the long-term outcomes of renal transplantation from Hbs Ag-positive donors to Hbs Ag-negative recipients. Material/Methods: A total of 78 patients who underwent renal transplantation in our clinic between January 2006 and May 2014 were included in the study. Patients were divided into 2 groups: Group 1: Donor Hbs Ag (+) (n=26, Hbs Ab (-), Hbe Ag (-), Hbe Ab (+), Hbc Ig total (+) and HBV DNA (+), male/female (M/F): 16 (61.5%)/10 (38.5%), and Group 2: Donor Hbs Ag (-) (n=52, M/F: 41 (78.8%)/11 (21.2%). Hbs Ab levels were similar in recipients in both groups. Data were collected retrospectively. Analyses were performed by using SPSS 20.0 software, and patient and graft survival were measured by using Kaplan-Meier survival curve and compared by using the log-rank test. Results: Demographic data were similar in the 2 groups. The rate of acute Hepatitis B infection was significantly higher in Group 1 than in Group 2 [n=3 (11.5%) vs. n=0 (0%), respectively, p=0.012]. Acute hepatitis B attacks were detected in vaccinated patients. Graft survival rates (groups 1 and 2, respectively; at 1st, 3rd, 5th and 8th years: 95% vs. 96%, 95% vs. 94%, 85% vs. 88%, 85% vs. 82%, p=0.970) and patient survival rates (p=0.098), acute rejection rates (p=0.725), delayed graft function, chronic allograft dysfunction, new-onset diabetes after transplantation (NODAT), cytomegalovirus infection, and the need for postoperative dialysis and plasmapheresis were similar between groups. Conclusions: Our study revealed that the risk of developing acute hepatitis B was higher in patients renally transplanted from Hbs Ag (+) donors, but the other clinical outcomes were similar between groups.Öğe Evaluating mean platelet volume as a new indicator for confirming the diagnosis of necrotizing pancreatitis(Edizioni Luigi Pozzi, 2015) Erbis, Halil; Aliosmanoglu, Ibrahim; Turkoglu, Mehmet Akif; Ay, Enver; Turkoglu, Ahmet; Ulger, Burak VeilBACKGROUND: The aim of the present study is to discuss the possible role of mean platelet volume as a new predictor in the diagnosis of necrotizing pancreatitis. METHODS: Study subjects are arranged in three different groups: Group I; control group (n= 40), Group II; acute pan-creatitis (n= 40), Group III; necrotizing pancreatitis (n= 36). Demographic data and mean platelet volume values are recorded retrospectively. RESULTS: Mean platelet volume of patients in Group II was 7.9 +/- 0.53, while in Group III patients' it was 7.2 +/- 0.52 (p<0.001). When we compared the study groups with ROC analysis, results demonstrated that cut off value of necrotizing pancreatitis patients as 7,8 (area under curve: 0.857), sensitivity as 86.1% and specificity as 72.5%. CONCLUSION: The current study shows that mean platelet volume in necrotizing pancreatitis patients is significantly reduced compared to that of patients in the control and acute pancreatitis group.Öğe HEPATOPULMONARY SYNDROME RELATED PORTAL HYPERTENSION(Wiley-Blackwell, 2015) Erbis, Halil; Calli, Iskan; Mutlu, Fatih; Ulger, Burak Veli; Tuna, Yasar; Ozturk, Bunyamin; Yilmaz, Vural Taner[Abstract Not Available]Öğe Mean Platelet Volume/Platelet Count Ratio: A New Diagnostic Parameter for Necrosis in Adhesive Small Bowel Obstruction-A Retrospective Cohort Study(Int College Of Surgeons, 2015) Ulger, Burak Veli; Erbis, Halil; Turkoglu, Ahmet; Gumus, Metehan; Gul, Mesut; Arikanoglu, Zulfu; Bozdag, ZubeyirAbdominal adhesions are still one of the most common causes of intestinal obstruction. A major challenge in adhesive small bowel obstruction (SBO) management is to detect ischemia as early as possible to avoid necrosis and resection. Elevated mean platelet volume and decreased platelet count have been associated with worse disease course for various ischemic diseases in many clinical studies. The objective of the current study was to evaluate the predictive value of the mean platelet volume/platelet count ratio for patients with small bowel obstruction. Data for patients with adhesive small bowel obstruction, admitted to the general surgery department of Dicle University Hospital between November 2010 and March 2014, were reviewed retrospectively. Mean platelet volume (MPV)/platelet count (PC) ratio values, demographic data, vital signs, and laboratory blood test results of the patients were analyzed. Mean platelet volume/platelet count ratio was higher in bowel necrosis group, while there were no differences between the groups in terms of mean platelet volume values. Mean platelet volume and mean platelet volume/platelet count ratio was higher in patients who underwent surgical treatment. The cutoff value with the highest sensitivity and specificity for MPV/PC ratio was 0.02855 (sensitivity 68%, specificity 65%) for predicting bowel necrosis in patients with adhesive SBO. Mean platelet volume/platelet count ratio is associated with the failure of the conservative management and the presence of bowel necrosis in patients with adhesive small bowel obstruction.Öğe Nebivolol Ameliorates Hepatic Ischemia/Reperfusion Injury on Liver But Not on Distant Organs(Taylor & Francis Inc, 2015) Ulger, Burak Veli; Erbis, Halil; Turkcu, Gul; Ekinci, Aysun; Turkoglu, Mehmet Akif; Ekinci, Cenap; Yilmaz, Vural TanerIntroduction: Hepatic ischemia/reperfusion injury may occur after large tumor resection and liver transplantation procedures. Nitric oxide was shown to have protective effects on ischemia/reperfusion injury. Nebivolol is a compound that has been reported to improve nitric oxide release. We evaluated the effects of nebivolol in a rat liver ischemia/reperfusion model. Methods: A total of 40 rats were randomly divided into four groups (n = 10 each). Group I underwent only laparotomy, Group II was administered nebivolol and then underwent laparotomy, Group III underwent laparotomy and hepatic ischemia/reperfusion, and Group IV was administered nebivolol and then underwent laparotomy and hepatic ischemia/reperfusion. Serum AST, ALT, urea, and creatinine levels, and TAS and TOS levels of liver, lung, and kidney tissues were determined. Histopathological determination was also performed. Results: Nebivolol significantly reduced liver function tests in group IV, but it did not improve renal functions. Oxidative stress and abnormal histopathological findings were found to be reduced in liver tissue in group IV. Although the oxidative stress was increased after hepatic ischemia/reperfusion, nebivolol could not reduce the oxidative stress in kidney tissue. There were no significant differences between group III and group IV in terms of the histopathological changes in kidney tissue. There were no significant differences in lung tissue between the groups. Conclusions: The results of this study suggest that nebivolol has protective effects on liver but not on distant organs in a hepatic ischemia/reperfusion injury model. These experimental findings indicate that nebivolol may be useful in the treatment of hepatic ischemia/reperfusion injury.Öğe RECONSTRUCTION OF SEGMENT 5 AND 8 VEINS IN RIGHT LOBE LIVING DONOR LIVER TRANSPLANTATION: AKDENIZ UNIVERSITY EXPERIENCE(Wiley-Blackwell, 2015) Aliosmanoglu, Ibrahim; Ulger, Burak Veli; Erbis, Halil; Tuna, Yasar; Ozturk, Bunyamin; Yilmaz, Vural Taner; Dinckan, Ayhan[Abstract Not Available]Öğe RETRO-URETERAL INTERNAL HERNIA AFTER SIMULTANEOUS PANCREAS-KIDNEY TRANSPLANTATION: A VERY RARE CASE(Wiley-Blackwell, 2015) Ulger, Burak Veli; Aliosmanoglu, Ibrahim; Erbis, Halil; Yilmaz, Vural Taner; Ozturk, Bunyamin; Calli, Iskan; Mutlu, Fatih[Abstract Not Available]Öğe AN UNUSUAL CAUSE OF BILIARY OBSTRUCTION AFTER LIVER TRANSPLANTATION: FASCIOLA HEPATICA(Wiley-Blackwell, 2015) Erbis, Halil; Ulger, Burak Veli; Aliosmanoglu, Ibrahim; Ozturk, Bunyamin; Yilmaz, Vural Taner; Dinckan, Ayhan[Abstract Not Available]
