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Öğe Beneficial effects of Beta-carotene injections prior to treatment with PGF2? on the fertility of postpartum dairy cows(Ecole Nationale Veterinaire Toulouse, 2012) Ay, S. S.; Kaya, D.; Kucukaslan, I.; Agaoglu, A. R.; Emre, B.; Handler, J.; Findik, M.This study examined the effects of Beta-carotene (beta C) injections before estrus synchronization with PGF(2)alpha on fertility parameters in cows. A total of 124 postpartum (pp) cows were used. In GI (n=25), beta C (Carofertin (R), 0.4 mg/kgBW, i.m.) was injected on d 15 and 45 pp. In GII (n=25), beta C was administered on d 15 pp. In GIII (n=25), beta C was administered on d 45 pp. In GIV (n=25), beta C was injected on d 35 and 45 pp. GV (n=24) was set aside as a control group. All animals received PGF(2)alpha (Iliren (R), 0.0015 mg/kgBW, i.m.) on d 50 and 61 pp. Blood samples were collected on d 15,48 and three days after each beta C injection. The overall pregnancy rate was determined to be higher in GI (100%) and GIV (88.0%) than GV (70.8%) (P<0.01). The number of services per conception was the lowest in GI (1.4) and GII (1.4), while days of first service were lower in GIII (90.3 d) and GIV (90.8 d) (P<0.05). The insemination index was found to be lowest in GI (1.4). These results suggest that two administrations of beta C in the early and late pp period before administering PGF(2)alpha can improve fertility. It was concluded that when serum beta C concentrations remain high for a long time (30d) as a results of beta C injections, fertility can be improved.Öğe Clinical and endocrinological effects of two different treatments for the induction of abortion in bitches(Wiley-Blackwell, 2011) Kaya, D.; Kucukaslan, I.; Agaoglu, A.; Ay, S.; Schafer-Somi, S.; Emre, B.; Bal, Y.[Abstract Not Available]Öğe The effects of aglepristone alone and in combination with cloprostenol on hormonal values during termination of mid-term pregnancy in bitches(Elsevier Science Bv, 2014) Kaya, D.; Kucukaslan, I.; Agaoglu, A. R.; Ay, S. S.; Schaefer-Somi, S.; Emre, B.; Bal, Y.This study was designed to assess endocrine changes associated with termination of midterm pregnancy after use of two different protocols. For this purpose we compared the effects of aglepristone (AGL) alone and in combination with cloprostenol (CLO) on serum concentrations of progesterone (P-4), estradiol (E-2) and relaxin (RLN) measured at shortterm intervals during the abortion period in bitches. Fourteen pregnant bitches between day 25 and 32 of gestation were used in the study. In the AGL group (n = 7), aglepristone was administered solely (10 mg/kg body weight (BW), subcutaneously, once daily on two consecutive days) whereas in the AGL-CLO group (n = 7), aglepristone (dosage as in AGL group) and cloprostenol (1 mu g/kg BW, subcutaneously, same with aglepristone) were combined. All pregnancies were successfully terminated 5.2 1.6 days after initiation of treatments, which was significant in both groups (P> 0.05). At the time of the start of abortion (SA) and the end of abortion (EA), the mean P4 concentrations were 26.6 7.3 and 12.0 6.4 ng/ml in AGL group, and 2.7 0.7 and 0.9 0.1 ng/ml, in AGL-CLO group, respectively (P< 0.01). Serum E-2 concentrations were significantly higher (P< 0.05) in AGL group at 42, 48, 54 hand SA after initiation of treatment. In the AGL-CLO group, serum RLN concentrations did not significantly change from the initiation of treatment to EA (P> 0.05). However, markedly higher RLN concentrations (P< 0.05) were observed in the AGL group at 48 h (1.5 0.7 ng/ml) and at SA (1.6 0.5 ng/ml). The results of the present study indicate that changes in the hormonal concentrations affect the mechanism of abortion in different ways. Further in depth studies investigating changes in the expression of hormone receptors inside the ovary, endometrium and placenta might be helpful to our understanding of the endocrinological differences observed in this study. (C) 2014 Elsevier B.V. All rights reserved.Öğe Evaluation of endometrial echotexture and cervical cytology in cows during and after treatment of endometritis(Georg Thieme Verlag Kg, 2014) Kucukaslan, I.; Kaya, D.; Emre, B.; Bollwein, H.; Ozyurtlu, N.; Mulazimoglu, S. B.; Aslan, S.Objective: The aim of this study was to evaluate changes in the endometrium by using echotexture parameters during and after treatment of endometritis with intrauterine administration of an intrauterine antiseptic solution (Lotagen (R), 3% metacresolsulphonic acid and formaldehyde) in cows which became pregnant after treatment. Material and methods: According to the severity of endometritis 21 cows were divided into three groups: El (slight, n = 7), E2 (moderate, n = 8), E3 (severe, n = 6). The control group (C, n = 11) consisted of cows without endometritis that did not receive an intrauterine medication. A software (Bs200 Pro (R)) was used to evaluate echotexture parameters Contrast (CON), Gradient (GR), Homogeneity (HUM), Mean Gray Level (MGL) of images taken during the examinations at hours (h) 0, 1 and 6 and days (d) 2, 3, 5 and 10. Results: At 0 h, GR was significantly lower in group E2 than in groups El and C (p < 0.05). There was an increase in GR values between 0 h and 10 d in group E2 and E3, but a decrease during the same time interval in group C (p < 0.05). In contrast, CON values of group E2 were lower (p < 0.05) at 0 h compared to other timepoints of examination and lower than in group C. HOM values were lower (p < 0.05) in groups El, E2 and E3 than in group Con d 5 and d 10. HUM values were higher at 1 h compared to 6 h, d 2 and d 10 in group E3 (p < 0.05). By contrast to GR values, HUM values were higher in group C at 6 h and d 10 than they were in group E3. MGL values of group E2 were higher (p < 0.05) than in group C until d 10 and higher (p < 0.05) in group E3 than in group C at 6 h after treatment. In group E2 an increase of MGL values until d 2 was followed by a decrease (p < 0.05). Conclusion: Echotexture parameters determined by the evaluation of sonographic B-mode images reflect changes in the endometrium and could be used for the evaluation of the recovery period after treatment of endometritis.Öğe Use of Echo-texture Parameters for the Determination of Different Degree Endometritis in Cows and Evaluation of the Recovery Period after Treatment(Wiley-Blackwell Publishing, Inc, 2009) Kucukaslan, I.; Kaya, D.; Emre, B.; Ozyurtlu, N.; Aslan, S.[Abstract Not Available]
