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    The effects of bilateral adrenalectomy on mandibular condyle of rat
    (Indian Veterinary Journal, 2008) Zengingul, A. I.; Ketani, M. A.; Baskan, S. Z.; Elitok, O. M.
    This study was aimed to evaluate the scaning electron microscope changes of mandibular condule in adrenalectomised rats.
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    Öğe
    Renal amyloidosis in cattle with inflammatory diseases
    (Blackwell Publishing, 2008) Elitok, O. M.; Elitok, B.; Unver, O.
    Background: The association of inflammatory diseases such as traumatic reticuloperitonitis (TRP), mastitis, metritis, and pododermatitis with renal amyloidosis in cattle is poorly described. Hypothesis: Serum amyloid A (SAA) levels are elevated during inflammatory diseases, and renal amyloidosis is formed as a complication. Animals: This study was conducted with 82 crossbred cattle with mastitis (n = 18 cows), metritis (n = 11 cows), TRP (n = 30 cows), and pododermatitis (n = 23 : 15 cows and 8 beef cattle). Ten clinically healthy cows served as controls. Methods: Hematological, urinary, and blood parameters, including SAA, were measured by an automated procedure provided with trade kits. Determination of amyloidal structures was made by histopathological examination of renal biopsy specimens. Results: At the end of this trial, amyloidosis was detected in 5 cows displaying typical nephrotic syndrome, with hypoproteinemia and proteinuria in combination with polyuria and weight loss. Furthermore, it was observed that cows with renal amyloidosis had significantly higher (P < .01) total leukocyte counts, serum and urine enzyme activities, and urea and creatinine concentrations, with lower serum total protein concentrations, when compared with animals without renal amyloidosis. Conclusions and Clinical Importance: The incidence of AA amyloidosis in cattle in this study suggests that cattle with mastitis, metritis, and pododermatitis have a high prevalence of systemic amyloidosis in response to inflammation.