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    Distally based subcutaneous veins for venous insufficiency of the reverse posterior interosseous artery flap
    (Wiley-Blackwell, 2016) Özalp, Burhan; Elbey, Hüseyin; Aydın, Atakan; Özkan, Türker
    BackgroundThe reverse posterior interosseous artery flap (PIAF) provides soft, thin, and pliable tissue for upper extremity reconstruction without sacrificing any major arteries of the hand. The authors performed a new technique that included one extra distally based subcutaneous vein within the pedicle to diminish venous insufficiency and they aimed to present the results of reconstruction with this technique. Patients and MethodsTwelve patients with a mean age of 30years (range 5-52years) underwent reverse PIAF surgery. The defects were located on the hand and wrist, with a mean area of 57.8cm(2) (range 20-99cm(2)). After the skin between the distal edge and the pivot point of the flap was elevated, the most reliable subcutaneous vein was chosen, chased, and included within the flap. ResultsThe average size of the PIAF was 6x5cm to 12x9cm (mean area: 64.4cm(2)) and the median follow-up time was 13months (range 4-16months). The mean quick Disabilities of the Arm, Shoulder and Hand (DASH) score was 21.4, indicating a low degree of disability. Of the 12 patients, ten were very satisfied and two were satisfied with the result of the reconstruction. All but one flap survived completely. One flap was nearly totally lost due to arterial insufficiency after hemodialysis. We observed no venous congestion or insufficiency in the patients. ConclusionsSubcutaneous veins may be reliable and useful for overcoming major drawbacks associated with reverse flow posterior interosseous artery flap and for diminishing flap loss due to venous insufficiency.
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    Effects on alveolar bone of diabetes mellitus induced by streptozotocin in rats. Histopathologic and immunohistochemical study
    (Universidad de la Frontera, 2018) Yılmaz, Nezih; Uysal, İbrahim; Eratilla, Veysel; İrtegün, Sevgi; Ferman, Rojda Güneş Uysal; Eratilla, Elif; Elbey, Hüseyin; Uysal, Ersin; Deveci, Buşra; Deveci, Engin
    The purpose of this study was to investigate effects of diabetes mellitus (DM) on the alveolar bone with histopathological and immunohistochemical methods. Wistar rats were divided into two groups, control and diabetes group. Control group was fed standard rat chow and drinking water for 8 weeks. Single dose (Streptozotocin) STZ (55 mg/kg), was dissolved in sodium citrate buffer and introduced intraperitoneal injection. Diabetes group and control group were compared in terms of glucose values. The blood glucose concentration in diabetic rats was significantly high (p <0.05). In diabetes group; periodontal membrane and the dilation of blood vessels, hemorrhage has also been a significant increase in inflammatory cells. In the diabetes group, osteonectin showed positive expression in periodontal membrane and showed negative expression in osteocytes of alveolar bone. Osteopontin expression in fibroblast cells and periodontal membrane collagen fibrils was positive, alveolar cells, osteocytes and bone matrix bone was found positive. Diabetes results showed that there formed periodontitis; due to the increase in inflammation inhibiting bone formation delaying the development of early bone cells.