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    Can the Density of Mineralized Dental Tissues (Dentin and Enamel) Be Measured and Compared with 3D Cone Beam Computed Tomography in Cases of Ectodermal Dysplasia?
    (Int Scientific Information, Inc, 2022) Yavuz, Yasemin; Akleyin, Ebru; Dogan, Mehmet Sinan; Goncharuk-Khomyn, Myroslav; Akkus, Zeki
    Background: Since 3-dimensional cone beam computed tomography (CBCT) started to be used in dentistry, mineral density can now be examined with computer software from the data on the images obtained. Detailed and clear im-ages at different slice intervals can be obtained with CBCT, and mineral density can be measured from the im-age data on a computer with a Hounsfield unit (HU) scale. In addition to the broad opportunities presented by CBCT, this feature has presented a wider perspective to researchers. Material/Methods: In this study, the CBCT images obtained from patients with the genetic disorder of ectodermal dysplasia were compared with the images of a control group to determine differences in mineralization of the teeth and to show that these could be compared by measuring the mineral density of dentin and enamel tissues using the HU scale on data from CBCT images. This opens new opportunities for cognitive and implementation research. Results: In the study, CBCT images of 14 ectodermal dysplasia and 14 control group cases previously obtained for vari-ous reasons were used. Mineral density measurements were made from 4 different regions of the teeth of the ectodermal dysplasia and control groups (incisor edge of the crown, the center buccal, cervicale line, and apex of the teeth), and the groups were compared. Conclusions: The aim of this study was to provide a new overview of the feasibility and suitability of mineralization mea-surement of dentin and enamel dental tissues with CBCT in ectodermal dysplasia and control groups.
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    Effect of electromagnetic fields and antioxidants on the trace element content of rat teeth
    (Dove Medical Press Ltd, 2017) Dogan, Mehmet Sinan; Yavas, Mehmet Cihan; Yavuz, Yasemin; Erdogan, Sait; Yener, Ismail; Simsek, Ibrahim; Akkus, Zeki
    The purpose of this study was to examine the possible effect of extremely low-frequency electromagnetic fields (ELF-EMFs), from a high-voltage source, on rat teeth in terms of changes in trace elements (TEs) and the effect of antioxidants (melatonin [MLT] and Ganoderma lucidum [GL]) in counteracting these effects. We used adult male Wistar albino rats with a mean weight of 250-300 g and divided the rats into eight groups. The groups were subjected to an ELF- EMF that was applied with a high- voltage line for 8 hours/day for 26 days (Groups I, II, and III) or 52 days (Groups V, VI, and VII). Groups IV and VIII were the 26- and 52- day control/sham groups, respectively. Groups II and VI were treated with GL, and Groups III and VII were treated with MLT. MLT and GL were administered daily based on the weight of the animals and appropriate standards. At the end of the study, the rats were euthanized, and their anterior teeth were extracted. The teeth were preserved in pure water before evaluating the major TEs. At the end of the study, TE concentrations (in mg/kg) were assessed in the control and test groups. Compared with Group V, statistically significant differences in the concentrations of zinc (Zn) and strontium (Sr) were found for Group VII (ELF- EMF + MLT) (P< 0.05). Therefore, ELF- EMF exposure can change the content of certain TEs in teeth and, after administering MLT and GL, the values of some of the TEs return to normal.
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    Evaluation of stress distribution of a new restorative material and composite resin: a finite-element analysis study
    (Taylor & Francis Ltd, 2017) Dogan, Mehmet Sinan; Demirci, Fatih; Eratilla, Elif; Eratilla, Veysel; Yavuz, Yasemin; Unal, Mehmet
    Glass carbomer cement is a new dental material developed from the traditional glass ionomer cements. It has better mechanical and chemical features when compared to the conventional glass ionomer cements. The purpose of this in silico investigation was to examine the influence of glass carbomer and composite resin materials with class I cavity design on stresses happening in the inlay. Finite-element analysis and three-dimensional modelling were used to examine the stress in the glass carbomer and hybrid composite inlays resulting from a 300-N point load on occlusal surfaces. Two different inlay materials, glass carbomer cement and hybrid composite resin, were evaluated. The maximum von Misses stress values in the composite resin inlays were significantly lower than those in the glass carbomer inlays. The results from this study showed that the resistance of the glass carbomer against the forces was higher than that of the composite resin inlays. The stresses were concentrated mostly at similar regions. The obtained results suggest that glass carbomer may be recommended as a preferred filler restorative material in teeth with much structure loss.
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    A microbiological assessment of the oral hygiene of 24-72-month-old kindergarten children and disinfection of their toothbrushes
    (Biomed Central Ltd, 2014) Celepkolu, Tahsin; Toptanci, Ismet Rezani; Bucaktepe, Pakize Gamze Erten; Sen, Velat; Dogan, Mehmet Sinan; Kars, Veysel; Aslanhan, Hamza
    Background: The objective of this study is to assess the index of decayed, missing and filled teeth (DMF-T), habit of brushing teeth, and the microbiological agents accumulating on the children's toothbrushes for 4 weeks and response of these agents to disinfection via a chlorhexidine solution, then compare those results with the education and income levels of the children's parents. Method: Included in the study were 187 children (96 in the control group and 91 in the experiment group - chlorhexidine) chosen randomly from 600 kindergarten children whose ages ranged from 24 months to 72 months. The children selected had not taken any antibiotics, antimicotics for three months and dental treatments during this trial. The distribution of these children to the groups was also done randomly. After performing a survey for the education, occupation, and income status of the parents, the children were examined and the number of decayed teeth was recorded. The children were given toothbrushes, toothpaste (with fluroide), and the solutions (including distilled water and chlorhexidine) for four weeks under the condition that toothbrushes were returned at the end of each week. The 14 different microbiological agents observed as a result of the assessment of the samples taken in the first week were also included in the assessments of the samples taken over the four-week period. Results: The decrease in the DMF-T index was found to be meaningful according to the differences in education, income, and occupation status of the parents. Of all the samples taken from the toothbrushes, the bacteria with the greatest rate of reproduction included Streptococcus mutans, Escherichia Coli, Pseudomonas aeuroginosa, Enterococcus spp, Staphylococcus epidermidis and Candida albicans. Except for Candida albicans, the other microorganisms taken as samples from the toothbrushes reproduced less overall. In the group using the solution with chlorhexidine, a meaningful decrease in bacterial reproduction was discovered compared to the control group. Conclusion: The findings of this study show that the education, occupation, and socioeconomic situations of the parents should be considered when discussing children's oral and dental health. Moreover, the study shows that disinfection of toothbrushes in order to prevent reinfection and contamination oral flora with the bacteria again is important in terms of preventive medicine and family-children health.
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    Three-dimensional finite-element analysis of two ceramic inlay restorations with different cavity designs
    (Taylor & Francis Ltd, 2015) Guven, Sedat; Akdogan, Mehmet; Oz, Cihan; Dogan, Mehmet Sinan; Unal, Mehmet; Unal, Server; Sahbaz, Cafer
    The aim of this in silico investigation was to examine the influence of two ceramic inlay materials with different cavity designs on stresses in the inlay. Finite-element analysis and three-dimensional modelling were used to examine the stress in ceramic inlays resulting from a 250-N point load on occlusal surfaces. The adhesion properties and von Mises stress values in the enamel, dentin, ceramic materials and cement linings were simulated. Two ceramic inlay materials: porcelain ceramic (Empress II, Ivoclar Vivadent, Liechtenstein) and zirconia ceramic (ICE Zirkon, Zirkonzahn SRL, Gais, Italy), as well as two cavity corner designs: rectangular and rounded, were evaluated. The obtained von Mises stress results indicated that the maximum and minimum forces were concentrated in the enamel and dentin, respectively. The stress values in the dentin and inlay material were similar in the porcelain ceramic and zirconia ceramic groups. However, in the enamel, the stress values in the zirconia ceramic group were significantly lower than those in the porcelain ceramic group. Additionally, cavities with rounded corners were subject to significantly less stress compared to those with rectangular corners. Thus, the zirconia ceramic inlay demonstrated better performance under applied stress, based on the reduced stress values in the tooth structure. Cavities with rounded corners showed less stress than those with rectangular corners, which could be attributed to the enhanced stress distribution capabilities of rounded corners.