Yazar "Doğan, Mehmet Sinan" seçeneğine göre listele

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    Clinical and radiological findings, SEM analysis and evaluation of caries risk in ectodermal dysplasia cases
    (Taylor & Francis, 2022) Yavuz, Yasemin; Akleyin, Ebru; Akdağ, Mehmet Zülküf; Çolak, Mehmet; Doğan, Mehmet Sinan; Kotanlı, Sedef
    Ectodermal dysplasia (ED) consists of many different combinations of irregularities that include developmental defects that occur in two or more of the following tissues: teeth, nails, skin, hair and sweat glands. The aim of this study was to evaluate the possible carries risk, perform scanning electron microscopy (SEM) mineral analysis in ectodermal dysplasia cases and describe the oral aspects. Ectodermal dysplasia cases, 41 patients (22 males and 19 females, aged 1.5 to 45 years), had a clinical examination. SEM analyses were performed from teeth that had to be extracted from ED cases for various reasons. Forty-one patients had tooth agenesis (from hypodontia to anodontia), multiple caries, hair and nail dystrophy. Also, extra orally they had sparse or absent hair, a short face, an unusual facial concavity, maxillary retrusion and relative mandibular protrusion. Differences between tooth samples were determined by SEM analyses. SEM analyses showed that the mineral content of ED teeth was lower than that of normal teeth and the surface properties of dentin and enamel were different. It is necessarily to support this observation with more comprehensive research. When dentists examine ED patients, they should consider the oral mucosa for excessive dryness and increased dental caries and should conduct a comprehensive, multidisciplinary approach to these patients in order to improve their dental, masticatory and caries conditions.
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    Diyarbakır devlet hastanelerine başvuran kişilerde hepatit ve HIV seroprevelansi
    (Harran Üniversitesi, 2018) Doğan, Mehmet Sinan; Eratilla, Veysel; Eratilla, Elif
    Amaç: Viral hepatitler ve HIV enfeksiyonu perinatal, parenteral ve cinsel yolla yüksek oranda bulaştırıcılık gösterir. Günümüzde bu bulaşıcı hastalıklar önemli küresel sağlık sorunlarıdır. Bu çalışmanın amacı, 2012, 2013 ve 2014 yılları arasında HAV IgG, HBsAg, anti-HBs, anti-HCV ve anti-HIV seropozitiflik oranlarının değişimini belirlemektir.Materyal ve Metod: Bu çalışmada, 1 Ocak 2012 ve 31 Aralık2014 tarihleri arasında Diyarbakır eğitim ve araştırma Hastanesi polikliniklerine başvuran 125129 hastanın kan örnek sonuçları cinsiyet ayrımı yapılmadan retrospektif olarak incelenmiştir. Alınan kan örnekleri CMIA (Chemiluminescent Microparticle İmmunoassay) yöntemi ile (Architect İ2000 SR, USA) çalışılmıştır.Bulgular: HBsAg açısından incelenen 125129 serum örneğinin 14176’inde (%11,32) HBsAg pozitifliği, anti-HBs açısından incelenen 124914 serum örneğinin 55803’sında(%44,7) anti-HBs pozitifliği, anti-HCV açısından incelenen 109340 örneğin 1013’sında(%0,93) anti-HCV pozitifliği, HAV IgG açısından incelenen 1511 örneğin 767’sinde(%50,76) HAV IgG pozitifliği, anti-HIV açısından incelenen 97501 örneğin sadece51’inde (%0,0005) anti-HIV pozitifliği saptanmıştır.Sonuç: Sonuç olarak, viral hepatitler ilimiz için önemli sağlık problemleridir. Aşılama, enfeksiyon kontrol programları ve halkın eğitimi yeni enfeksiyonların riskini azaltabilir. Anti-HIV pozitifliği ilimizde çok düşük bulunmuştur.
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    Ektodermal displazili olgularda klinik ve radyolojik bulguların incelenmesi
    (Fırat Üniversitesi Tıp Fakültesi, 2019) Doğan, Mehmet Sinan; Ataş, Osman; Yavuz, İzzet; Tekin, Samet
    Amaç: Ektodermal displazi; deri, tırnak, saç, ter bezleri ve diş gibi ektoderm kaynaklı dokuları etkileyen ve nadir olarak rastlanan kalıtsal bir hastalıktır. Bu çalışmada fakülte hastanemize başvuran ektodermal displazili olgulardaki; sistemik ve dental bulguların klinik ve radyolojik olarak değerlendirilmesi amaçlanmıştır.Gereç ve Yöntem: Çalışmamızda 2006-2017 yılları arasında Dicle Üniversitesi Diş Hekimliği Fakültesi hastanesine diş eksikliği şikayetiyle başvuran, 49 ektodermal displazi olgusu retrospektif olarak değerlendirildi. Klinik değerlendirmede saç, tırnak, deri, diş, burun, ter bezleri ve benzeri malformasyonlar incelendi. Radyolojik muayenede; geleneksel radyografi ve konik ışınlı bilgisayarlı tomografi kullanılarak diş germleri, çene kemiği vediş köklerine bakıldı.Bulgular: Çalışmamızda yaş ortalaması 11,9±4,6 olan, 25’i kadın (%51,1), 24’ü erkek (%48,9) toplam 49 hasta değerlendirildi. Çalışmadaki ED’lihastaların oral bulguları ile ilgili olarak; %100 (n =49) diş eksikliği, %100 (n =49) mandibular protrüzyon ,%75,51 (n =37) konik diş, %6,12 (n =3)kök şekil anomalileri görülmüştür. Klinik muayenesinde ise terleme problemi %77.55 (n =38), saç-kıl anomalisi %95.91 (n =47), anormal parmak vetırnaklar %83.67 (n =41) belirlendi.Sonuç: ED’nin temel bulguları oral ve maksillofasiyal bölgede oluştuğundan, estetik ve çiğneme problemleri ortaya çıkmaktadır. Bu nedenle dişhekimliğinde multidisipliner tedavi gerektiren özel bir yere sahiptir. Bu hastalarda yaşam kalitesini artırmaya yönelik olarak tıp ve diş hekimlerininkoordineli çalışması oldukça önem kazanmaktadır.
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    Güneydoğu Anadolu Bölgesi popülasyonunda maksiller sinüs septa prevalansının konik ışınlı bilgisayarlı tomografi ile retrospektif olarak değerlendirilmesi
    (Harran Üniversitesi Tıp Fakültesi, 2022) Güneş, Nedim; Ağın, Hatice Demircan; Doğan, Mehmet Sinan; Eratilla, Veysel
    AMAÇ: Bu çalışmanın amacı; sinüs septanın, Güneydoğu Anadolu bölgesi popülasyonundaki prevelansını konik ışınlı bilgisayarlı tomografi (KIBT) ile retrospektif olarak değerlendirmektir. YÖNTEM: Bu retrospektif çalışmada, 2015-2020 yılları arasında Dicle Üniversitesi Diş Hekimliği Fakültesi, Ağız, Diş ve Çene Cerrahisi Anabilim dalına çeşitli nedenlerle başvuran 948 hastaya ait toplam 1896 sinüs, KIBT görüntüleri incelenmiştir. 948 hastaya ait (510 kadın, 438 erkek) sinüs septa KIBT görüntüleri değerlendirildi. Sinüs septa tespit edilen vakalar; cinsiyet, lokalizasyon (anterior, orta ve posterior), lateralizasyon (unilateral, bilateral) açısından elde edilen tüm veriler kaydedildi ve istatistiksel olarak analiz edilerek görülme sıklıkları belirlenmiştir. BULGULAR: 18-65 yaş aralığındaki 948 hastanın KIBT görüntüleri değerlendirilmiştir. Bu hastaların maksiller sağ ve sol çeneleri incelenmiş ve 303 hastada toplam 322 sinüs septa tespit edilmiştir.284 hastada tek sinüs septa görülürken, 19 hastada ikişer sinüs septa görülmüştür. 510 kadın hastada (1020 septa incelendi) 178 septa tespit edildi (%9). 438 erkek hastada ise (876 septa incelendi) 144 septa tespit edildi (%7). 322 sinüs septanın, 284 tanesinde tek septa görülürken (%88); 19 tanesinde çift sinüs septa (%5) görülmüştür. Sinüs septa; anteriorda 81 adet (%25), ortada 153 adet (%47), posteriorda 88 adet (%27) olarak tespit edilmiştir. Sinüs septa kadın hastaların 6’sında (510 hastada) çift taraflı görüldü (%1). 166 hastada tek taraflı olarak görüldü. Sinüs septa erkek hastaların 3’ünde ( 438 hastada) çift taraflı görüldü (%0,6). 138 hastada tek taraflı olarak görüldü. SONUÇLAR: Çalışmamızda sinüs septa prevalansı toplamda Güneydoğu Anadolu Bölgesi popülasyonunun % 16’sında görülmüştür. Sinüs septa, kadın hastalarda daha yüksek oranda izlenmiştir. Çift sinüs septa %5 olarak görülmüştür. Bu yüzdelik değerler; p<0,05 için istatistiksel olarak anlamlı kabul edilmiştir.
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    Post-trauma root fracture in teeth with incomplete root development: A case report
    (Innovare Academics Sciences Pvt. Ltd, 2017) Doğan, Mehmet Sinan; Maharani, Diah Ayu; Kusdhany, Lindawati S.; Adiatman, Melissa; Yavuz, İzzet
    Objective: Oblique root fractures consist of multiple, angled fracture lines extending from the root canal to the periodontal membrane along the long axis of the tooth. Oblique root fractures are injuries with poor prognosis which are rarely observed in teeth in which the root development is complete. Methods: A clinical and radiological inspection was performed of an eight-year-old patient who presented at our clinic for dental trauma. Luxation and oblique sectional root fractures in the maxillary incisors were found. The patient’s root development was incomplete. He was treated with dental reposition. Fixation to the adjacent primary canine teeth was carried out using a 0.4 mm full circle orthodontic wire for fractured teeth with a semi-rigid splint. Stabilization of the teeth was ensured to protect the vitality of the fractured teeth. A splint was inserted under local anaesthesia and removed a month later. Results: The absence of pathological symptoms was determined radiologically and clinically. It was shown during a radiological examination of the patient a year later that root development inthe teeth with a root fracture had continued. There were no pathological complications. Conclusion: The current study finding of high recovery potential in young permanent teeth with root fracture is supported by those of other studies in the literature. Recovery in this case was successful because the patient presented timeously at the clinic after the trauma, there was a lack of infection, and the splint was only in situ for a month.
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    The protective effect of melatonin and Ganoderma lucidum against the negative effects of extremely low frequency electric and magnetic fields on pulp structure in rat teeth
    (Taylor and Francis Ltd., 2017) Doğan, Mehmet Sinan; Yavaş, Mehmet Cihan; Günay, Ayşe; Yavuz, İzzet; Deveci, Engin; Akkuş, Zeki; Tanık, Abdülsamet; Akdağ, Mehmet Zülküf
    Background/aim: The aim of this study was to determine whether Extremely low frequency electric and magnetic field (ELF-EMF) had any harmful effects on dental pulp tissue and examine histologically whether melatonin (MLT) and Ganoderma lucidum (GL) play a protective role against these harmful effects. Material and method: A total of 56 adult, male Wistar Albino rats were used in the study. The rats were separated into 8 equal groups and were exposed to ELF-EMF, generated by high voltage source, for 8 hours/day for 26 days–Groups I, II and III and for 52 days-Groups V, VI and VII. For sham-control groups (Groups IV and VIII for 26 and 52 days), rats were placed into same experimental set-up as exposure groups and same procedure was applied except ELF-EMF exposure. GL (20 mg/kg/day) and MLT (10 mg/kg/day) were administered by oral gavage and the intraperitoneal route respectively. At the end of the study, the rats anterior teeth were examined immunohistochemicaly using vimentin and vascular endothelial growth factor (VEGF). Results: Degeneration in the odontoblast cells, inflammatory cell infiltration, dilatation of the blood vessels and haemorrhagic changes were determined in the pulp of the rats in Groups I and V. A statistically significant difference was determined in the groups treated with MLT and GL (p < 0.05). Conclusion: It was determined that exposure to ELF-EMF induced histological changes in the dental pulp of rats, the using of MLT and GL could have a protective effect against these effects.
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    Reliability and accuracy of cone-beam computed tomography voxel density and linear distance measurement at different voxel sizes: A study on sheep head cadaver
    (Association for Dental Sciences of the Republic of China, 2017) Güngör, Enes; Doğan, Mehmet Sinan
    Background/purpose The reliability and accuracy of linear distance and voxel density (VD) measurements are very important in dentistry. The purpose of this study was to assess the accuracy and reliability of linear distances and VD measurements of cone-beam computed tomography (CBCT) at different voxel sizes. Materials and methods Eighteen-millimeter linears of size 40 gutta-percha were prepared in fresh sheep head. The head was scanned using CBCT with 0.25, 0.3, and 0.40 voxel sizes. Standard linear distances of gutta-percha were measured in panoramic CBCT images at 0.25, 0.3, and 0.4 voxel sizes. VD measurements were made separately on spongeous bone of palatal surfaces of the roots of teeth 4, 5, and 6 of maxilla and on cortical bone of teeth 4, 5, and 6 regions of the left and right hemimandibles through cross-sectional imaging. Results We found that linear distance measurements on panoramic image of CBCT were slightly lower than physical measurements. A significant difference was not found for the gutta-percha linear distances and cortical VD measurements at different voxel sizes (P ≥ 0.05). The correlation between measurements of VD at different voxels in cortical bone was greater than 0.85 (P = 0.000). Conclusion Linear distance measurements on the sheep head cadaver of 0.25, 0.3, and 0.4 voxel sizes were similar and reliable when compared with physical measurements. In minimizing radiation exposure, VD measurement of cortical bone at 0.4 voxel-based CBCT could be used to estimate cortical bone density. However, studies should be performed on the human head cadaver.
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    THE STRESS DISTRIBUTION EVALUATION OF TWO DIFFERENT POST TYPES WHICH USED IN ANTERIOR TEETH WITH COMPLICATED CROWN-ROOT FRACTURE: A FINITE ELEMENT ANALYSIS METHOD
    (2018) Günay, Ayşe; Karaali, Abdullah Emre; Doğan, Mehmet Sinan
    Aim: The aim of this study was to compare the stressdistribution under artificial forces that simulate thebiting forces of the two different post types used inmaxillary anterior teeth that had complicated crownrootfractures and to determine the region where thestress occurred. For this purpose, a finite elementanalysis method was used.Material and method: In the study, Glass fiber post(Group I) and carbon fiber post (Group II) were usedto model tooth with complicated crown-root fracture,which would be horizontal in the cervical region of thefracture line. In the model, fractured teeth fragment(coronal and root fragments) were reattachment to bypost. The force of 100N was applied to the incisal ofthe teeth at 900angles to the groups (longitudinalaxis). Finite element analysis method was used toevaluate stress resulting from force and to obtain athree-dimensional model. Analyzes were done with theANSYS program (ANSYSRel.6.0, ANSYS Inc., Houston,TX, USA).Results: As the results of the analysis, the resistanceof glass fiber post against the forces was higher thanthe carbon fiber post. The stresses were concentratedmostly at the palatinal regions in group I and II.Conclusion: The rehabilitation of esthetic andfunctional for anterior group teeth with complicatedcrown-root fractures was favorable glass fiber postthan carbon fiber post.