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    EFFICACY OF PULSED AND CONTINUOUS THERAPEUTIC ULTRASOUND IN MYOFASCIAL PAIN SYNDROME: A RANDOMISED CONTROLLED STUDY
    (Bmj Publishing Group, 2014) Ilter, L.; Dilek, B.; Batmaz, I.; Ulu, M. A.; Sariyildiz, M. A.; Nas, K.; Cevik, R.
    [Abstract Not Available]
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    The impact of ankylosing spondylitis on female sexual functions
    (Nature Publishing Group, 2013) Sariyildiz, M. A.; Batmaz, I.; Inanir, A.; Dilek, B.; Bozkurt, M.; Bez, Y.; Karakoc, M.
    The aim of this study was to explore the impact of ankylosing spondylitis (AS) and the disease-related variables, psychological status and the quality of life on the female patients' sexual function measured according to the Female Sexual Function Index (FSFI). Thirty-seven sexually active female AS patients and 33 healthy controls were enroled in this study. Their demographic data were evaluated and the generalised pain in patients with AS was assessed according to the visual analogue scale (0-100 mm). Laboratory tests were conducted in order to measure the C-reactive protein (CRP) and erythrocyte sedimentation rates (ESR) of the patients. In comparison to the healthy control group, patients with AS had significantly lower scores in each of the five domains of the FSFI except for the pain domain (P<0.05). The disease activity, functional status, quality of life, radiological score and CRP levels were negatively correlated with the FSFI (P<0.05). No significant correlation was observed with the disease duration, smoking status, depression, anxiety, pain and ESR when the total scores and the scores from the domains of the FSFI were compared. The sexual function is impaired in female patients with AS. This impairment in the sexual function is especially related to the functional status and disease activity among the clinical and laboratory parameters.
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    Relation of asymmetric dimethylarginine and cardiac involvement in systemic sclerosis
    (Publisaude-Edicoes Medicas Lda, 2014) Dag, Sevin; Budulgan, M.; Dilek, B.; Batmaz, I; Ariturk, Z.; Nas, K.; Cevik, R.
    Objectives: The heart is a commonly involved organ in systemic sclerosis (SSc) and pulmonary hypertension is a commonly observed complication that is associated with poor prognosis in this disease. Asymmetric dimethylarginine (ADMA) is an endogenous inhibitor of nitric oxide synthases. In this study, we aimed to contribute to an early diagnosis of cardiac involvement by evaluating ADMA and tissue Doppler echocardiographic findings in patients with SSc. Methods: 30 SSc patients without clinical cardiac symptoms and 30 controls were included. Plasma ADMA levels were measured and tissue Doppler echocardiography examination was carried out for all participants. Systolic and diastolic functions were assessed; pulmonary arterial systolic pressure and mean pulmonary arterial pressure were measured. Results: The patient and control groups demonstrated a significant difference with regard to right ventricular free wall tissue Doppler late diastolic wave, pulmonary arterial systolic pressure, right ventricular ejection fraction, and right ventricular diastolic dysfunction values. ADMA levels were significantly higher in SSc patients and also in active patients compared to inactive patients. No significant relationship between ADMA and echocardiographic parameters was found. Conclusion: Tissue Doppler echocardiography is capable of revealing impaired right ventricular functions and increased pulmonary arterial systolic pressure before the occurrence of any cardiac clinical symptoms in patients with SSc. Serum ADMA levels were increased in SSc and in patients with active disease.