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Öğe Henna - Induced hemolytic anemia and acute renal failure(2001) Devecioğlu C.; Katar S.; Doğru Ö.; Taş M.A.Henna is a traditional cosmotic agent and is used worldwide, especially in the Middle East. Its active agent is lawsone (2-hydroxy-1,4-naphthoquinone). Henna is not only applied to hands or hair as a cosmotic agent in traditional ceremonies, but is also applied to the body on lesions in the treatment of seborrheic dermatitis or fungal infections. However, its application over the body or in newborns is rare. Here we report a 27-day-old boy who developed hemolytic anemia and acute renal failure following topical application of henna to his abdomen, intertriginous region and legs to treat diaper rash.Öğe Intracranial hemorrhage in newborns due to vitamin K deficiency(2006) Katar S.; Özbek M.N.; Güzel A.; Devecioğlu C.; Ecer S.The late hemorrhagic disease of the newborn results from vitamin K deficiency and the bleeding in these patients is usually intracranial. In this study, clinical and laboratory findings of 10 cases with intracranial bleeding are described. Of these 10 patients, nine had not been given prophylactic vitamin K, while one had received prophylaxis. Eighty percent were male and their age was between 8 and 29 days. All patients were term newborns, with one born in hospital and nine at home. There was no history of medication use, diarrhea or trauma, and all newborns were solely breast-feeding. Prothrombin, partial thromboplastin and coagulation times were prolonged in all cases. Four hours after intravenous administration of vitamin K (2 mg), all these values returned to normal levels. Intracranial bleeding was evacuated surgically in one patient. Two patients died. In conclusion, we believe that every newborn should receive prophylactic vitamin K. In addition, it appears that a second dose of vitamin K is required during the first month of life due to the possibility of late hemorrhagic disease of the newborn despite initial prophylaxis.Öğe Pyridoxine dependent early epileptic encephalopathy in a newborn: Case report(2012) Taşkesen M.; Yarami?s A.; Gözü Pirinççioğlu A.; Devecioğlu C.Pyridoxine-dependent seizures, characterized by various intractable seizure types, usually occur during the first hours of life. Typically, pyridoxine-dependent seizures are unresponsive to anticonvulsant drugs and they respond only to immediate administration of pyridoxine hydrochloride. We have reported a 5-day-old boy who was presented with flexor type tonic spasms with clustering beginning in the first hours of his life. The spasms were refractory to several anticonvulsant drugs but they responded well to pyridoxine treatment. This report emphasizes the importance of considering pyridoxine-dependent epileptic encephalopathy in newborn babies who are unresponsive to anticonvulsant drugs. Copyright © 2012 by Türkiye Klinikleri.
