Yazar "Deveci, Ildem" seçeneğine göre listele

Listeleniyor 1 - 2 / 2
  • [ X ]
    Öğe
    Histological evaluation of rat larynx in experimental polycystic ovary syndrome model
    (Springer, 2012) Deveci, Hande Senem; Deveci, Ildem; Habesoglu, Mehmet; Surmeli, Mehmet; Kinis, Vefa; Eriman, Murat; Gunes, Pembegul
    This study aimed at studying the histopathological effects of hyperandrogenemia and estrogen deficiency on larynx mucosa in experimentally designed polycystic ovary syndrome of female rats. Two groups of experimental polycystic ovary syndrome model were composed in healthy female rats by per oral letrozole administration of for 21 and 42 days. Also a control group which only took vehicle (saline) for 42 days was designed. Laryngeal mucosa and ovaries of all animals were examined histopathologically by light microscopy and the serum hormone levels were analyzed using a solid-phase, two-site chemiluminescent enzyme immunometric assay. Statistically significant edema, vascular engorgement, inflammation, cilia loss and differentiation of goblet cell distribution were observed when the control group and study groups were compared (p < 0.01). In serum hormonal analysis there was a significant increase in levels of androgens and decrease in levels of estrogens. In addition, polycystic appearance of ovaries in letrozole-administered groups and normal appearance of ovaries in control group have been proven histopathologically. Polycystic ovary syndrome which causes estrogen deficiency and hyperandrogenemia in fertile ages resulted in histopathological changes in laryngeal mucosa.
  • [ X ]
    Öğe
    Role of Allergy in Primary Acquired Nasolacrimal Duct Obstruction
    (Lippincott Williams & Wilkins, 2012) Eriman, Murat; Kinis, Vefa; Habesoglu, Mehmet; Habesoglu, Tulay Erden; Surmeli, Mehmet; Deveci, Ildem; Deveci, Senem
    Objective: Our objective was to determine the role of allergy in primary acquired nasolacrimal duct obstruction. Methods: A total of 41 patients were enrolled in the study, 41 of whom had primary unilateral acquired nasolacrimal duct obstruction. All patients included in the study were evaluated by anterior rhinoscopy, endoscopic nasal examination, and multiprick skin test to reveal allergic rhinitis. Results: Allergy incidence was found to be high in study group. This was statistically significant (P < 0.05). Conclusions: Although primary acquired nasolacrimal duct obstruction seems to be an ophthalmologic problem, rhinologic problems have great importance in etiology. Detailed endoscopic examination and multiprick skin test will reveal the possible role of allergic rhinitis. This may increase the success rate both of the conservative treatment options and of the surgical treatment.