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    The Diagnostic Accuracy of Endometrial Sampling in Endometrial Hyperplasia
    (2017) Deregözü, Ayşegül; Karaçor, Talip; Acet, Mustafa; Gül, Talip; Evsen, Mehmet Sıddık; Ağaçayak, Elif; Hatirnaz, Safak
    OBJECTIVE: Endometrial hyperplasia is a premalignant lesion characterized with hyperplastic changes in endometrial gland and stromal structures. Its incidence is not exactly known. This study evaluated the accuracy of endometrial sampling of the patients whose pathological results were endometrial hyperplasia and had undergone hysterectomy (paraffin sections). STUDY DESIGN: Patients that diagnosed with endometrial hyperplasia by endometrial biopsy and/or hysterectomy at Dicle University School of Medicine Department of Obstetrics and Gynecology between January 2006 and July 2014 were retrospectively evaluated. Sensitivity, specificity, and positive and negative predictive values of endometrial biopsy to predict postoperative hysterectomy result were calculated. Discrete results in endometrial sampling and hysterectomy were recorded separately. Statistical analyses were conducted with corresponding appropriate methods. RESULTS: Mean ages of pre and postmenopausal patients were 42.6±4.8 (28-50) and 57.7±7.7 (50- 79) years, respectively. For the efficiency of endometrial sampling to predict definite pathologic diagnosis, sensitivity was 71.9%, specificity was 87.5%, positive predictive value was 79.3%, and negative predictive value was 82.3%. When the accuracy of endometrial sampling with the pathologic diagnosis was evaluated, 38 patients had accurate (47.5%), and 42 patients had discrete (52.5%) results. CONCLUSION: The presence of atypia determines the treatment in patients with endometrial hyperplasia. Hysterectomy should not be the first option in endometrial hyperplasia patients without atypia, and medical treatment and curettage options should be considered. Experienced staff should perform and evaluate endometrial samplings. We consider that this will increase the success in diagnosis, and could change treatment options.
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    Is Caesarean Myomectomy a Safe Procedure? A Comparative Study
    (2016) İnegöl, İlknur Gümüş; Başaranoğlu, Serdar; Ağaçayak, Elif; Acet, Mustafa; Deregözü, Ayşegül; Gül, Talip
    OBJECTIVE: Uterine myomas are the most common benign pelvic tumours observed during the reproductive period.Increased risks of haemorrhage and postoperative morbidity lead professionals to avoidmyomectomy at the time of Cesarean (C-section). The present study retrospectively analysed the dataof patients who had undergone C-section only and those that had undergone C-section and simultaneous myomectomy. STUDY DESIGN: The data of 42 patients (Group 1) who had underwent caesarean myomectomy andof 50 patients underwent C-section only (Group 2) out of 92 patients that had been taken into C-sectionon the basis of obstetric indications were retrospectively analysed in this study. The relevant patient datawere recorded with the inclusion of demographic data, gestational week, and preoperative and postoperative laboratory findings. Types, locations and sizes (the largest diameter) of individual myomas wereidentified and noted.RESULTS: The mean diameter of myomas was 66.3±30.2 mm. Ten patients that had underwent caesarean myomectomy (23.8%) developed a need for intensive care. No statistically significant differencewas found in laboratory parameters between Group 1 and Group 2.CONCLUSION: Caesarean myomectomy, when performed by experienced obstetricians, does not leadto a significant increase in maternal morbidity and mortality. Although the short-term effects of this procedure are known, there is a need for the conduct of more comprehensive studies to establish its longterm effects on fertility or how it will affect the next pregnancy processes