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Öğe Arnold-Chiari syndrome (type I)(2006) Taşdemir, Nebahat; Tacar, Orhan; Demirant, Ayda; Taşdemir, SerhanArnold-Chiari syndrome is a rare malformation of the brain that is generally present from birth. This type of brain malformation may be associated with other anomalies including hydrocephalus, myelomeningocele, syringomyelia and spina bifida. There are 3 types of Arnold-Chiari malformation (types I, II and III). The clinical symptoms of all 3 types include torticollis, opisthotonus, headache, vertigo, vocal cord paralysis, apnea, nystagmus, dysphagia and ataxia. The Chiari I malformation is considered to be congenital, although there have been reported cases of an acquired form. The incidence of this malformation has been found to be ?0.56% via magnetic resonance imaging (MRI) studies. The malformation is characterized by a displacement of the cerebellar tonsils, medulla and the fourth ventricle into the spinal canal. The diagnosis can be difficult because not all patients present the classical symptoms of herniated tonsils. However, this anomaly may be diagnosed with MRI. Here we describe a case study of a 22-year-old female patient in a neurology clinic complaining of both headache and vertigo. We determined via MRI that there was a hernia of the cerebellar tonsillar located inferiorly to theforamen magnum. On the other hand the width of the fourth ventricle and the parenchyma tissue of the cerebellum were normal. This type of malformation may prove to be the cause of headache and vertigo in some people. MRI may therefore be a useful tool to aid in the accurate diagnosis of their symptoms.Öğe The comparative investigation of left ventricle papillary muscle arteries in different species(Saudi Med J, 2006) Gumusalan, Yakup; Ozbag, Davut; Ozden, Hdmi; Saruhan, Berna G.; Demirant, AydaObjectives: To determine whether similar histologic findings exist in left ventricle papillary muscle arteries in different species and to elicit whether those animal hearts may be used as models for human heart in experimental studies related to papillary muscles. Methods: We examined 360 samples taken from the tip, mid-portion and base of papillary muscles in 60 normal adult hearts (15 each from human, dog, sheep, goat). The samples were obtained from Dicle University and Kahramanmaras Sutcu Imam University, Turkey and the study was conducted in June-September 2004. Tissues were processed by routine histologic methods, stained with hematoxylin-eosin and van giesson, and later evaluated under a light microscope. Results: While the values of human and dog heart resembled each other by means of left ventricle papillary muscle arteries, the hearts of sheep and goat were also found to be similar. The number of thin walled arteries increased from the tip (18%) to the base (48%), intermediate walled arteries decreased from the tip (56%) to the base (14%), thick walled arteries decreased from the tip (62%) to the mid-portion (38%). The differences among human and animals were not statistically significant in any group. We found that the thickness values of papillary muscle arterial walls at the tip, mid-portion and base varied from 4.86 mu m to 107.7 mu m in all species. The difference among values of human and animals was not significant statistically (p > 0.05). Conclusion: The values for arterial walls of tip, mid-portion and base of papillary muscles were similar between human and dog, sheep and goat. These morphologic findings in human and animal hearts of different species prove that anatomists, cardiologists, experimental investigators, pathologists and physiologists may benefit from the hearts of those animals as a good model to imitate the human heart in experiments concerning papillary muscles.Öğe Effects of lumbosacral angles on development of low back pain(Journal Of Musculoskeletal Pain, 2014) Çağlayan, Mehmet; Tacar, Orhan; Demirant, Ayda; Oktayoğlu, Pelin; Karakoç, Mehmet; Çetin, Abdurrahman; Em, Serda; Bozkurt, Mehtap; Uçar, Demet; Nas, KemalObjective: Low back pain [LBP] is an important health issue due the diagnosis and treatment expenses and loss of workforce it leads to. Biomechanical changes in the vertebral column caused by changes in the lumbosacral angles [LSAs] may lead to LBP. The purpose of this study was to assess body mass index [BMI] and LSAs in patients with LBP and investigate the association between LBP, LSAs and BMI. Methods: Lumbar lordotic angle [LLA], LSA, sacro-horizontal angle [SHA] and sacral inclination angle [SIA] were measured in 117 patients with chronic LBP and 85 healthy normal controls [HNCs] by means of lumbosacral radiography. In addition, association between LSAs, BMI and LBP was investigated. Results: There were no significant differences between patients and HNCs regarding LSAs and BMI. LLA was lower in male patients with LBP compared to male HNCs without LBP [p = 0.013]. In addition, SIA [p = 0.002] and BMI [p = 0.006] were higher in female patients with LBP compared to male patients with LBP. It was found that an increase in LLA increased the risk of having LPB by approximately 1.04-folds [ranging from 1.01 to 1.08; p = 0.045]. On the other hand, no association was found between LSAs and BMI. Conclusion: Changes in LSAs may cause LBP. An increase in LLA may be influential in increasing the risk of LBP. Therefore, measurement of LSAs may guide the physician who is to make clinical decisions in examination of patients with LBP.Öğe Genç ratlarda iskemi-reperfüzyonun ince barsaktaki hasarı üzerine E vitaminin etkisi(1998) Deveci, Engin; Göral, Vedat; Canoruç, Fikri; Tacar, Orhan; Demirant, Ayda; Yılmaz, FahriIskemi-reperfüzyon üzerine antioksidan ajanların etkileri iyi bilinmektedir. Bu çalışmada hayvanlara 3 gün 300mg/kg E vitamini enjekte edildi. Üçüncü gün A.mesenterica superior atravmatik klemps ile iskemi için 30 dakika süre ile tutuldu ve sonra 45 dakika reperfüzyona maruz kaldı. Jejenum'dan alınan kesitler histolojik olarak incelendi ve iskemi-reperfüzyonun olumsuz etkileri ve aynı zamanda bu olumsuz etkiler üzerine E vitaminin koruyucu etkisi incelendi.
