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    Assessment of patients with thrombotic thrombocytopenic purpura
    (2010) Demir C.; Altintaş A.; Paşa S.; Ali Kaplan M.; Küçükzeybek Y.; Ayyildiz O.
    Thrombotic thrombocytopenic purpura (TTP) is a severe microvascular occlusive thrombotic microangiopathy characterized by systemic platelet aggregation, organ ischemia, profound thrombocytopenia, and fragmentation of erythrocytes. Unexplained occurrence of thrombocytopenia and anemia should prompt immediate consideration of the diagnosis and evaluation of peripheral blood smear for evidence microangiopathic hemolytic anemia. Excellent remission and survival rates were achieved by therapeutic plasma exchange. We reviewed characteristics and response rates to plasmapheresis of our TTP patients. A total of 25 cases were diagnosed. The parameters of hemoglobin and platelet were analyzed at presentation, as well as the number of plasmapheresis sessions and adjunctive treatment given. We found a response rate of 80 percent to plasma exchange. Response was better in 23 patients who presented with idiopathic TTP. Response was poor in patients with TTP secondary to underlying metastatic carcinoma. Two patients relapsed and one of the relapsed patients died. Plasmapheresis is mandatory and effective for primary TTP. Plasmapheresis may not be effective in all instances, especially if TTP is secondary to underlying disseminated cancer.
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    Öğe
    Opinions of the 6th class matter and heat unit on the technique of the students working with the station technique
    (SciencePark Science, Organization and Counseling, 2018) Cakmak M.; Demir C.
    The aim is to reveal the views of the sixth grade Matter and Heat Unit on the technique of the students who work with the station technique. Qualitative method was used. The study group of the study was 25 students in the sixth grade who attended Ataturk Secondary School in the Cinar district, they were in the second year of the 2016–2017 academic year. They worked with the station technique. The application was applied in a total of 16 lessons including the Matter and Heat Unit. The researcher conducted the implementation process. Five stations including poetry, story, picture, song and slogan were created and worksheets and workbooks were used. Semi-structured interview form consisting of five questions was applied to 25 students to get opinions of the students about the station technique. Their answers were categorised and the percentages and frequencies were found. Research results determined that the students enjoyed the station technique and they wanted to use this technique in the other subjects of the Science course and in the other courses. © 2018 SciencePark Research, Organization & Counseling. All rights reserved.