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Öğe 900 MHz radiofrequency radiation has potential to increase the expression of rno-miR-145-5p in brain(University of Dicle, 2019) Dasdag S.; Erdal M.E.; Erdal N.; Tasdelen B.; Kiziltug M.T.; Yegin K.; Akdag M.Z.Interaction between radiofrequency radiation (RFR) and miRNA which plays paramount role in growth, differentiation, proliferation, and cell death by suppressing one or more target genes, is still unknown. Therefore, the purpose of this study is to investigate the effects of long term 900 MHz mobile phone exposure on some of the miRNA in brain tissues (sham: 7; Exposure: 7)., which were kept in appropriate laboratory conditions for the second phase of our previous study [5]. It is remembered that rats in the exposure group were exposed to 900 MHz RFR for 3 h per day (7 days a week) for one year. For the aim of this study, expression of miRNAs such as rno-miR-22-3p, rno-miR-24-1-3p, rno-miR-132-3p, rno-miR-145-5p, rno-miR-181a-5p, rno-miR-186-5p, rno-miR-195-5p, rno-miR-219a-5p, rno-miR-221-3p and rno-miR-222-3p were investigated. Results indicated that long-term exposure of 900 MHz RF radiation increased only expression of rno-miR-145-5p (adj P * = 0.047) value where 1g average SAR value in brain was 0.198 W/kg. Our results indicated that chronic exposure of 900 MHz RFR has potential to increase expression of rno-miR-145-5p. Therefore, further studies are necessary to understand the relation between 900 MHz mobile phone exposure and diseases related to the expression of rno-miR-145-5p. © University of Dicle.Öğe Alteration in body composition of elite professional female players in a premier league volleyball bout(2009) Cerit S.; Akdag M.Z.; Dasdag S.; Karakoc Y.; Celik M.In this study, we aimed to investigate the effects of single bout of volleyball on body composition in elite professional female players. Sixteen elite professional female players that play volleyball in a club in Turkish Premier League were enrolled in the study. Prior to one league match (pre-exercise) bioelectric impedance analyzes were performed using a bioelectric impedance analyzer. After the final period (3rd set) of match was ended, bioelectric impedance analyzes were repeated (post-exercise). There were no significantly changes in body mass index, body cell mass, body capacitance, lean body mass, and basal metabolic rate at post-exercise time. Body resistance, reactance and fat mass were all significantly lower than pre-exercise time (p<0.01). On the other hand, extracellular mass increased at post-exercise time, and that significances were found to be p<0.05. As an intense aerobic exercise, single bout of volleyball (three sets) decreases body fat mass at post-exercise time. This change is associated with decreases in body resistance and reactance. Excess lost of body fat may be related to frequently using anaerobic process for energy requirement in volleyball players and prolonged exercise for competition.Öğe Effect of extremely low frequency magnetic fields in safety standards on structure of acidophilic and basophilic cells in anterior pituitary gland of rats: An experimental study(2009) Akdag M.Z.; Dasdag S.; Ketani M.; Sagsoz H.After discovery of magnetite in the brain of several mammalian species including humans, it was suggested that the human brain is sensitive to magnetic fields. The present study investigated the effect of 100 ?T and 500 ?T extremely low frequency magnetic fields (ELF-MF), established guidelines by the International Commission on Non-Ionizing Radiation Protection (ICNIRP) for public and occupational magnetic field exposure limits at 50 Hz, on acidophilic and basophilic cells in the anterior pituitary gland of rats. 30 adult male Sprague Dawley rats were separated into three groups in this study (sham group: 10 and two study groups: 20). Rats in the study (experimental) groups separated equally into two groups that is 100 ?T and 500 ?T exposure groups. First experimental group rats exposed to 100 ?T while second experimental group exposed to 500 ?T ELF-MF for 2 hours per day (7 days in a week) during 10 months. For the sham group, the same experimental procedure was applied to the rats (2 hours/day/7 days in a week for 10 months) except ELF-MF exposure. After ELF-MF and sham exposure, the pituitary gland were removed totally to examine the structure of acidophlic and basophilic cells in the anterior pituitary gland of rats as histomorphometric and histochemical. Affinity against dye in acidophilic and basophilic cells of first experimental groups' rat was found lower than sham group. It means that degranulation may occur in sitoplasmic granuls of these cells. Disappearing in the affinity of Periodic Acid-Shchiff (PAS)-Orange-G in acidophilic and basophilic cells of second exposure group has been indicating high disappearing of granuls in these cells. No significant differences were found between sham and exposure groups in terms of the number of acidophilic and basophilic cells in the anterior pituitary gland (p>0.05). Although degranulation observed in acidophilic cells, the results were not found to be significant between experimental groups (p>0,05). However, degranulated basophilic cells were found significant between experimental groups (p<0,05). In conclusion, it was suggested that long-term ELF-MF exposure, which are the limits for public environmental and occupational magnetic field exposure guidelines, can affect affinity of PAS-Orange G in acidophilic and basophilic cells of the anterior pituitary gland in rats.Öğe Effect of microwaves on survival of some bacterial strains(Akademiai Kiado Rt., 1996) Atmaca S.; Akdag Z.; Dasdag S.; Celik S.While the inhibitory effect of microwave radiation on microorganisms is being researched intensively, how microwave radiation brings about this effect has been a matter of discussion. Some researchers support that this effect is of a thermal character, whereas some others maintain a non-thermal effect. In this work, 1 ml suspensions of Pseudomonas aeruginosa, Pseudomonas acidovorans, Staphylococcus aureus and Staphylococcus epidermidis bacteria were subjected to microwave radiation at 2450 MHz and 550 Watts for periods of 5, 6, 7, 8, 10, 12, 14, 16, 18, 20, 25 and 30 seconds. When each result was compared with the CFU/ml results obtained from unradiated control group bacterial suspensions derived from stock cultures, significant conclusions were attained (P<0.001). The same experiments were repeated with the application of conventional heating. The difference between the CFU/ml values of similar bacterial suspensions subjected to microwave radiation and conventional heating was significant (P<0.001). Concurrently, the fact that the effect was exacerbated upon increasing of liquid volume during the application of microwave radiation was established via the results obtained through the application of microwave radiation to 1 ml and 5 ml bacterial suspensions (P<0.001).Öğe Effect of mobile phone signals on electrical impulses of myelinated nerve fibres(University of Dicle, 2017) Yegin K.; Yegin E.G.; Dasdag S.One of the seldom studied effects of mobile phone radiation is its impact on impulse transmission in nerve fibers. Effects could be; although unlikely, stimulation of a nerve pulse, change in depolarization threshold rest potentials, conduction velocity, and energy spectrum of the impulse. To study these effects, 3D electromagnetic field distributions inside a volumetric pixel model of a human were simulated with a GSM antenna in proximity of hand. The electric field and SAR distributions due to a radiating antenna 10 mm away from hand were calculated for 0.8 W and 2 W peak pulsed GSM signals at 900 MHz. Maximum SAR in the hand was found to be 5.78 W/kg for 10 g average and 8.21 W/kg for 1g average. As the depth from skin surface increases, the probe readings can get as high as 20 mV and as low as 1 mV for 2-W peak-power transmission. Coupled signal voltage waveform along a myelinated nerve fibre was calculated and superimposed on nerve impulse at four different instances. Spectrums of the resulting impulse with and without GSM coupling were also compared to each other. The noise floor in the spectrum of the nerve impulse has increased due to presence of GSM signal. It was observed that GSM-signal coupling could distort the shape and the spectrum of the nerve impulse, but it did not reach a level to trigger an impulse from its resting potential nor perturb the nerve conduction velocity if only the induced electrical force is considered.Öğe Effects of radiofrequencies emitted from mobile phones on teeth and oral tissues(University of Dicle, 2017) Dasdag S.; Yavuz I.; Akdag M.Z.Number of various sources of wireless communication is had been incredibly increased in the recent decade. One of the most popular wireless communication equipment is mobile phones. However, another widespread part of wireless communications is Wi-Fis. As it is known, smart phones has many function such as speaking, Wi-Fi, bluetooth etc. Therefore, their radiofrequency radiation (RFR) level is higher than the first generation mobile phones. It means that smart phones emit higher RFR. The results of studies performed on the effects of RFR on animal or human indicated that mobile phones are not innocent. Because of that RFRs classified as 2B (Possible carcinogen) by World Health Organization in 2011. Most of the studies usually performed on RFR and health focused on the brain tumors and other diseases. No one pay attention to the potential health effects of this electromagnetic pollutant on oral tissues and teeth, which are one of the most RFR exposed parts of heads at the beginning. Although limited number of the studies had been done on oral tissues, the results of the studies are worth considering. Therefore, the aim of this review is to summarize the results of the limited studies here. In conclusion, the results of the studies investigated the effects of RF exposure on oral tissues and teeth indicated that uncontrolled exposures may have potential to cause some dental health problems. Finally, further studies including human studies are necessary to illuminate this topic.Öğe The effects of the microwave oven on pregnant and newborn rat kidneys(1997) Inaloz S.S.; Dasdag S.; Aslan A.; Bilici A.; Yayla M.Background: The increasing use of microwave radiation for industrial, scientific, medical and domestic purposes has resulted in growing concern about the biological effects of microwaves on man. Objectives: In this study, teratogenic effects of the microwave oven were investigated histologically on pregnant and newborn rat kidneys. Methods: Twenty-four pregnant Wistar- albino rats were separated into three groups (n=8), a control group (sham- exposed) and two experimental groups. The experimental gravid rats were confined in plexiglas cages which were placed next to the closed door of a microwave oven (power-output: 550W). In the first experimental group, the gravid rats were exposed to the microwave oven daily for 15 minutes whereas the gravid rats were exposed daily for 30 minutes in the second experimental group. Results: The physiological dilation of the renal tubules was observed in all dams. There was a positive correlation between the duration of exposure and the severity of necrosis. Necrosis of renal tubules together with normal glomeruli and stromal cells were seen in the first group of litters. Pronounced necrotic renal tissues and adrenal glands were observed only in the fitters of the second group. Conclusion: The teratogenic effects of the MW oven was observed especially in the second group of litters Nevertheless, pregnant users are not exposed to microwave radiation under the same conditions as in our experiment.Öğe Hormone levels of people occupationally exposed to radiofrequencies(1999) Dasdag S.; Balci K.; Kaya H.; Celik M.S.The present article intended to investigate some hormone levels of technicians in the radio-broadcasting, television (TV) and radio - link stations. The study was carried out on 43 technicians from 20 to 59 years age occupationally exposed to radiofrequency (RF) and microwave (MW) radiation. 20 unexposed and voluntary persons from 20 to 59 years age were accepted as a control group. We determined the levels of some hormones as triiodothyronine (T3), tetraiodothyronine (T4), thyroid stimulant hormone (TSH), free T4, estradiol, dehydroepiondrosterone sulfate (DHEA), testosterone, cortisol and progesterone in the technicians under investigation. The hormone levels of exposure groups were statistically compared with the unexposed control group. T3, T4, estradiol, testosterone and progesterone levels of technicians in the radio-link and TV transmitter stations were found to be significant (p < 0.05, p < 0.001). T3, T4, TSH, estradiol and progesterone levels of technicians in the broadcasting station were also found to be significant (p < 0.001). In conclusion some hormone levels of technicians under investigation were altered by RF/MW.Öğe An important biomechanical parameter in elite wrestlers: Pre and post trainning hand grip strength(2011) Kaynar O.; Dasdag S.Hand grip strength (a biomechanical parameter) plays an important role in daily life and especially during the sportive activities to get the maximum efficiency. Therefore, hand grip strength is an important indicator in wrestling in terms of performance. This study was carried out on 22 elite wrestlers who wrestle for professional Turkish wrestling clubs in Ankara. Hand grip strength of wrestlers in 66 kilogram category was only measured in this study for standardization. Maximum and minimum right and left hand grip strengths of the wrestlers were measured when the arms positioned in 90 o and 180 o degree angles. Each measurement was repeated three times. The results of the study were compared by using paired samples t test. MedCalc statistical program were used for the statistics. Although pre training hand grip strengths were found higher than post training hand grip strength the results were not found to be statistically significant(p>0.05). In conclusion, no significant difference was observed in hand grip stress of the elite wrestlers before and after training.
