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Öğe ANTI-TUBERCULOSIS DRUG RESISTANCE IN SOUTHEAST OF TURKEY(Carbone Editore, 2013) Dal, Tuba; Ozcan, Nida; Tekin, Recep; Tekin, Alicem; Celen, Mustafa Kemal; Ozekinci, Tuncer; Dal, T.Objective: Tuberculosis is a globally prevalent life-threatening infectious disease. In this study we aimed to evaluate antibiotic suscebtibility rates of Mycobacterium tuberculosis complex strains. Materials and methods: A total of 150 culture-positive samples were included in. Among culture positive samples 86 were Mycobacterium tuberculosis complex and 64 were non-tuberculous mycobacterium. Of Mycobacterium tuberculosis complex isolated samples 45 were Ziehl-Neelsen positive. Of 64 non-tuberculous mycobacterium isolated samples 15 were Ziehl-Neelsen positive. Mean age of the patients with tuberculosis was 37.74 +/- 20.53 and non-tuberculous mycobacterium isolated patients was 46.80 +/- 23.32. Antibiotic susceptibility testing was performed for the four first-line anti-tuberculosis drugs by BACTEC MGIT-960 instrument (Becton Dickinson). Of M. tuberculosis strains 41 % was resistant to at least one or more of the drugs (isoniasid 27.9%, ethambutol 8.13%, streptomycin 12.79 %, rifampicine 9.3 %). Of the strains 5.8 % was resistant to two, 3.4 % to three and 3.4 % to four drugs. Conclusion: Mycobacterium tuberculosis complex and drug resistance of this microorganism continued to be a problem for our country and non-tuberculous mycobacterium species may become a problem in the future. We thought that a strong and cost-effective tuberculosis control programme contributes to reduce the incidence of drug resistance in the community.Öğe ASSESSMENT OF THE UNDERLYING CAUSES OF IMMUNE THROMBOCYTOPENIA: TEN YEARS EXPERIENCE(Pergamon-Elsevier Science Ltd, 2016) Dal, M.; Karakus, A.; Dal, T.; Aydin, B.; Hattapoglu, E.; Ekmen, M.; Ulas, T.[Abstract Not Available]Öğe Evaluation of Adults with Acute Viral Hepatitis A and Review of the Literature(Soc Editrice Univ, 2013) Tekin, R.; Yolbas, I.; Dal, T.; Demirpence, O.; Kaya, S.; Bozkurt, F.; Deveci, O.Aim. In developing countries HAV infection is very common in the first years of life and it is often asymptomatic. However especially in regions of intermediate endemicity, exposure to the virus may delay and outbreaks of hepatitis A may be encountered in adults. The aim of this study is to evaluate the clinical and laboratory findings and risk factors of adults with acute viral hepatitis A. Materials and Methods. In present study we evaluated 203 patient with acute viral hepatitis A, who were admitted to four different hospitals of three cities of Turkey between January 2000-December 2011, retrospectively. The diagnosis of acute viral hepatitis A was performed by laboratory findings and clinically. Results. In a total of 203 patients, 120 (59.1%) patients were male and 83 (40.9%) were female. Mean age of cases with acute viral hepatitis A was 24.7 + 11.8 years (ranged 15 to 82 years old). Acute viral hepatitis A were seen in patient who were 15-20 years and 21-30 years old, commonly. Jaundice (74%), fatigue (68%), nausea-vomiting (56%) and dark urine (48%) were the most common symptoms in cases. Prolonged cholestasis (6.8%) was the most common atypical manifestation. Prolonged jaundice was more frequent in the cases with positive HBsAg (P<0.001). Conclusions. Acute viral hepatitis A can cause atypical presentations such as prolonged cholestasis, acute kidney injury and fulminant hepatitis. Some precautions such as routine vaccination program, improvement of hygiene conditions and informing people about it, should be taken for reducing of acute viral hepatitis A infection incidence.Öğe The evaluation of patients with burns during fifteen years period(Soc Editrice Univ, 2013) Tekin, R.; Yolbas, I.; Dal, T.; Okur, M. H.; Selcuk, C. T.Aims. Burn is a major health problem that cause of mortality, morbidity and psychological problems in children and adults throughout the world. The aim of this study was to evaluate the epidemiological, etiological features and outcomes of burns in the southeast region of Turkey. Patients and Methods. A total of 3010 burn patients (age vary between 2 month to 95 years old) that admitted to the Dicle University burn center during the 15 years period (1994-2008) were reviewed. Age, gender, demographic characteristics, length of hospital stay of patients, etiology and degree of burns, cause of nosocomial infections, the total body surface area (TBSA) percentage and outcomes were analyzed. Results. Of 3010 patients, 1602 (53.2%) cases were female and 1408 (46.8%) were male. The mean age was 10.51 +/- 13.45. The most of patients (58.1%, 1748 patients) were <= 5 years old, 19.9% (598) were 6-15, 20.1% (606) were 16-50 and 1.9% (58) were >= 51 years old. Burn type of cases were including: 1956 (65%) scalding burns, 624 (20.7%) flame burns and 430 (14.3%) electrical burns. Degree of burns were including: 22 (0.7%) first-degree, 2706 (89.9%) second-degree and 282(9.4%) third-degree burns. The mean of length of hospitalization was 13.25 +/- 10.77 days. The most frequent isolated microorganisms were Pseudomonas aeruginosa (55%, 553), Acinetobacter spp. (13%, 128), and Escherichia coli (8%, 78). Mortality rate was 4.6%. Conclusions. The epidemiology of burns may vary according to lifestyles, age, living conditions and socio-economic status among different regions and hospitals. Improvement of life conditions and socio-economic status, trainings, periodic studies of nosocomial infections and increasing the number of burn centers, would contribute to reduction of deaths due to burns.Öğe Evaluation of the relationship between preeclampsia and seropositivity of infectious disease in maternal plasma(Soc Editrice Univ, 2013) Soydinc, H. E.; Kan, I.; Dal, T.; Evsen, M. S.; Sak, M. E.; Ozler, A.; Turgut, A.Purpose. The aim of the present study was to investigate the association between maternal infections and preeclampsia. Materials and Methods. Fifty-four pregnant women with preeclampsia (study group) and 54 healthy pregnant women (control group) were enrolled in this study. Chlamydia pneumoniae (CP), Mycoplasma hominis (MH), Helicobacter pylori (HP), Cytomegalovirus (CMV), Herpes simplex virus type 2 (HSV-2), and Toxoplasma gondii (TG) antibodies were analyzed in the maternal plasma of all of the participants. Results. There was no difference in the demographic data between groups. Maternal plasma seropositivity for CP IgM; MH IgA and IgG; HP IgM, IgA and IgG; TG, CMV and HSV-2 IgM and IgG were not significantly different between the preeclampsia and control groups. The seropositivity for CP IgG was significantly higher in women with preeclampsia versus the control women. Conclusions. Our results suggested that preeclampsia is associated with CP IgG seropositivity.Öğe FASCIOLA HEPATICA ASSOCIATED WITH MONOCLONAL GAMMOPATHY OF UNDETERMINED SIGNIFICANCE(Pergamon-Elsevier Science Ltd, 2014) Karakus, A.; Dal, M. S.; Ekmen, M. O.; Yildirim, R.; Dal, T.; Ayyildiz, O.[Abstract Not Available]Öğe Seroprevalence of IgG anti-Toxocara canis antibodies and anti-Fasciola sp antibodies in patients with urticaria(Soc Editrice Univ, 2013) Dal, T.; Cicek, M.; Ucmak, D.; Akkurt, M.; Tekin, A.; Dal, M. S.; Tekin, R.Aims. Chronic urticaria (CU) is defined by recurrent episodes occurring at least twice a week for 6 weeks and generally characterized by the rapid appearance of wheals and/or angioedema and may be associated with parasitic infections. We aimed to investigate the seroprevalance of Toxocara canis and Fasciola species in patients with CU. Materials and Methods. We included 55 patients (in age 16-55) with urticaria admitted in study. As a control group we recruited 30 healthy volunteers they had no history of urticaria, rhinitis, asthma, atopic eczema/dermatitis syndrome (AEDS), or other relevant diseases. IgG antibodies to Toxocara canis and Fasciola species were investigated by ELISA method. Results. In a total of 55 patients (mean age: 31.85 +/- 8.92), 8 patients (14.5%) were positive for IgG antibodies to Toxocara canis. Among seropositive patients (mean age: 38.62 +/- 12.46) 6 patients were female. No patient was positive for Fasciola by ELISA. Six of Toxocara canis seropositive cases were frequently visited or lived in rural areas and had contact with pets. Conclusions. Patients with urticaria, should be tested for Toxocara canis and treated with anthelminthic drugs in endemics areas for toxocariasis.
