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Öğe Light and electron microscopic examination of exocrine pancreas using zinc Iodide-osmium tetroxide technique(Okajima Foria Anatomica Yaponika Henshubu, 1998) Atilla, Pergin; Akkuş, Murat; Deveci, Engin; Bilgin, Yılmaz; İnalöz, Serap; Dağdeviren, AttilaZinc iodide-osmium tetroxide (ZIO) fixation/staining technique is a metallophilic technique which has been used for the examination of various tissues and cell types. We examined the ZIO (+) cell types in rat exocrine pancreas to obtain further evidence for the significance of the reaction. Among mostly non-reactive pancreatic acinar cells there were ZIO (+) acinar cells of varying staining intensity. Zymogenic granules and centroacinar cells were completely non-reactive. Our electron microscopic findings support the view that the reactivity of the technique used is cell specific but not cell type or organelle specific.
