Yazar "Cingu, Kursat" seçeneğine göre listele

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    Activation of toxoplasma retinochoroiditis during pregnancy and evaluation of ocular findings in newborns
    (Springer, 2017) Turkcu, Fatih Mehmet; Sahin, Alparslan; Yuksel, Harun; Cinar, Yasin; Cingu, Kursat; Altindag, Suat; Deveci, Ozcan
    The purpose of this study was to evaluate patients with activation of toxoplasma retinochoroiditis during pregnancy and ocular findings in newborns. A total of 17 pregnant patients who were clinically and serologically diagnosed with ocular toxoplasmosis were retrospectively reviewed. After birth, ocular findings for all infants were recorded. The mean age of the patients was 29.08 +/- 5.71 years. In all cases, activation was present in only one eye. In 13 cases, anterior uveitis was associated with posterior uveitis. Visual acuity in all cases prior to treatment was 0.3 +/- 0.21 and increased to 0.55 +/- 0.29 after treatment. The mean gestational age of the patients was 19.76 +/- 8.71 weeks at the time of hospital admission. No case of toxoplasmic ocular involvement was identified in the infants on postnatal examination. In the case of toxoplasma retinochoroiditis during pregnancy, appropriate treatment and follow-up is very important to protect the newborns and to prevent impaired vision in mothers.
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    AUTHOR REPLY TO: Mean platelet volume in pseudoexfoliation syndrome and glaucoma
    (Wichtig Editore, 2014) Turkcu, Fatih Mehmet; Yuksel, Harun; Sahin, Alparslan; Cinar, Yasin; Yuksel, Hatice; Cingu, Kursat; sahin, Muhammed
    [Abstract Not Available]
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    Corneal perforation during Nd:YAG laser capsulotomy: a case report
    (Springer, 2013) Turkcu, Fatih Mehmet; Yuksel, Harun; Cingu, Kursat; Cinar, Yasin; Murat, Mehmet; Caca, Ihsan
    We report a case where corneal perforation developed during Nd:YAG laser capsulotomy. We present a 20-year-old male with the complaint of impaired vision in the right eye. Leukoma consistent with the incision line in the cornea and opacity in the posterior capsule were observed.
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    Demographic and etiologic characteristics of children with traumatic serious hyphema
    (Turkish Assoc Trauma Emergency Surgery, 2013) Turkcu, Fatih Mehmet; Yuksel, Harnn; Sahin, Alparslan; Cingu, Kursat; Ari, Seyhmus; Cinar, Yasin; Sahin, Muhammed
    BACKGROUND We aimed to evaluate the etiologic factors, complications, follow-up, and treatment outcomes in serious hyphema following blunt ocular trauma in childhood. METHODS The medical records of 136 patients diagnosed as grade 3 or 4 hyphema due to blunt ocular trauma between January 2006 and December 2011 were evaluated. Visual acuity (VA), complications, and medical and surgical treatments were analyzed. Factors affecting visual prognosis were compared in grade 3 and 4 hyphema cases. RESULTS The mean age of patients was 9.7+/-4 years. Etiologic factors for trauma were stone in 53 (39%), bead bullet in 25 (18.4%) and others in 58 (42.6%) patients. The most common complication of grade 3 and 4 hyphema was traumatic mydriasis (19.1%), followed by cataract (9.6%) and glaucoma (5.1%). Medical treatment was successful in 114 (83.8%) patients, and 22 (16.2%) patients underwent surgery. Mean initial and final VA of grade 4 patients were found to be significantly lower than those of grade 3 patients. CONCLUSION In grade 3 and 4 hyphema due to blunt trauma, visual prognosis worsened in the presence of additional ocular pathologies. Considering the bad visual prognosis of severe hyphema patients, prompt treatment and close follow-up may prevent complications resulting in poor VA.
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    Effects of smoking on visual acuity of central serous chorioretinopathy patients
    (Informa Healthcare, 2014) Turkcu, Fatih Mehmet; Yuksel, Harun; Sahin, Alparslan; Cinar, Yasin; Cingu, Kursat; Ari, Seyhmus; Sahin, Muhammed
    Background: The aim of this study was to evaluate the differences, in terms of visual outcome and treatment needs, between smokers and non-smokers central serous chorioretinopathy (CSCR) patients. Methods: The files of 252 patients diagnosed with CSCR who had presented to the Retina Unit of the Ophthalmology Clinic at Dicle University Medical School in Turkey were retrospectively evaluated. Eighty-four smokers, with a known history of smoking of at least one pack-year, and 133 non-smokers were included, whereas 35 patients with additional pathologies were excluded from the study. Results: Of the patients, 192 (88.5%) were male and 25 (11.5%) were female. The mean patient age was 38.8 +/- 8.1 years (range: 20-68 years). Visual acuity (VA) of the smoker and non-smoker groups was measured as 0.45 +/- 0.35 and 0.24 +/- 0.28 logarithm of the minimum angle of resolution (logMar), respectively, at the first visit; 0.19 +/- 0.29 and 0.06 +/- 0.14 logMar at the sixth month; and 0.07 +/- 0.14 and 0.02 +/- 0.05 logMar at the ninth month. VA measurements at presentation and during all examinations (1th, 6th and 9th month) were significantly different for the two groups. VA was lower in the smoker group. In 27 patients (12.4%), an additional treatment modality was needed. Of the 27 patients, only 8 (6%) were non-smokers, whereas 19 (22.6%) were smokers. There was no difference between groups in the recurrence rate during follow-up (p = 0.907); 14 (16.7%) smokers and 8 (19.0%) non-smokers experienced a recurrence. Conclusion: This study has shown that patients selected and who are current smokers have poorer vision and need longer treatment.
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    Evaluation of Intracameral Injection of Ranibizumab and Bevacizumab on the Corneal Endothelium by Scanning Electron Microscopy
    (Mary Ann Liebert, Inc, 2015) Ari, Seyhmus; Nergiz, Yusuf; Aksit, Ihsan; Sahin, Alparslan; Cingu, Kursat; Caca, Ihsan
    Purpose: To evaluate the effects of intracameral injection of ranibizumab and bevacizumab on the corneal endothelium by scanning electron microscopy (SEM). Methods: Twenty-eight female rabbits were randomly divided into four equal groups. Rabbits in groups 1 and 2 underwent intracameral injection of 1 mg/0.1 mL and 0.5 mg/0.05 mL ranibizumab, respectively; group 3 was injected with 1.25 mg/0.05 mL bevacizumab. All three groups were injected with a balanced salt solution (BSS) into the anterior chamber of the left (fellow) eye. None of the rabbits in group 4 underwent an injection. Corneal thickness and intraocular pressure were measured before the injections, on the first day, and in the first month after injection. The rabbits were sacrificed and corneal tissues were excised in the first month after injection. Specular microscopy was used for the corneal endothelial cell count. Endothelial cell density was assessed and comparisons drawn between the groups and the control. Micrographs were recorded for SEM examination. The structure of the corneal endothelial cells, the junctional area of the cell membrane, the distribution of microvillus, and the cell morphology of the eyes that underwent intracameral injection of vascular endothelial growth factor (VEGF), BSS, and the control group were compared. Results: Corneal thickness and intraocular pressure were not significantly different between the groups that underwent anti-VEGF or BSS injection and the control group on the first day and in the first month of injection. The corneal endothelial cell count was significantly diminished in all three groups; predominantly in group 1 and 2 (P<0.05). The SEM examination revealed normal corneal endothelial histology in group 3 and the control group. Eyes in group 1 exhibited indistinctness of corneal endothelial cell borders, microvillus loss in the luminal surface, excessive blebbing, and disintegration of intercellular junctions. In group 2, the cell structure of the corneal endothelium and intercellular junctions were normal. However, a relative reduction was observed in the microvillus density of endothelial cells. Although eyes in group 3 were morphologically similar to fellow eyes and the control group, disarrangement in endothelial cell borders was evident. Conclusion: The SEM examination pointed out deterioration in endothelial cell morphology after intracameral injection of 1 and 0.5 mg ranizumab. However, the effects of intracameral bevacizumab injection on corneal endothelial cells were similar to those found in fellow eyes and the control group. Further large-scale studies that examine the cellular changes by transmission electron microscopy are required to support the results of the present study that evaluates the structural changes in endothelial cells by SEM.
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    Mean platelet volume in pseudoexfoliation syndrome and glaucoma
    (Sage Publications Ltd, 2014) Turkcu, Fatih Mehmet; Yuksel, Harun; Sahin, Alparslan; Cinar, Yasin; Yuksel, Hatice; Cingu, Kursat; Sahin, Muhammed
    Purpose: Pseudoexfoliation (PEX) syndrome (PES) is characterized by the widespread deposition of abnormal extracellular fibrillary material on many ocular and extraocular tissues. The objective of this study was to evaluate the association among PES, PEX glaucoma (PEG), and mean platelet volume (MPV). Methods: Forty patients with PES (mean age 62.6 +/- 7.8 years), 31 with PEG (mean age 65.9 +/- 6.6 years), and 37 healthy individuals (control group) (mean age 64.0 +/- 7.1 years) were included in the study. The MPV of the 3 groups were compared. Results: Age and sex distribution were similar among groups (p>0.05). Mean MPV in PES, PEG, and control groups were 9.59 +/- 0.94 fl, 9.53 +/- 0.80 fl, and 7.7 +/- 0.67 fl, respectively. In the PEX group, MPV values were significantly higher than in the control group (p<0.05). However, there was no difference between the PES and PEG groups (p>0.05). Conclusions: The MPV values in both groups with PEX were higher than those in the healthy group.