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    Comparison of the effects of mandibular protruding devices on obstructive sleep apnoea patients and healthy volunteers
    (Churchill Livingstone, 2014) Acar, Mustafa; Saylisoy, Suzan; San, Turhan; Cingi, Cemal; Ay, Yazgi; Karabag, Aral; Turkcan, Irem
    Purpose: To evaluate upper airway diameter differences before and after placement of custom made mandible protruding devices (MPD) in OSAS group and to compare with control group using computerized tomography. Methods: The OSAS group was composed of 15 patients aged from 25 to 45 years with mild-moderate OSAS and the control group included 15 healthy volunteers, aged from 25 years to 44 years. On coronal and sagittal reformated CT images, anteroposterior (AP) and lateral (LAT) diameters at three levels (passing through soft palate [level 1], 5 mm above uvula [level 2] and 1 cm above the tip of epiglottis [level 3]) were measured before and after MPD placement in both groups. Results: LAT diameters at level 1, level 2 and AP diameter at level 2 in OSAS group were significantly lower than in control group before MPD placement. Only LAT diameters at level 2 in OSAS group were significantly lower than in control group after MPD placement. When we compared upper airway diameters before and after placement of the MPD within each group, statistically significant increase in diameters at all levels were observed. Conclusion: MPD is a cheap, easily usable device providing increase in upper airway diameters. (C) 2014 European Association for Cranio-Maxillo-Facial Surgery. Published by Elsevier Ltd. All rights reserved.
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    Effects of chlorhexidine/benzydamine mouth spray on pain and quality of life in acute viral pharyngitis: A prospective, randomized, double-blind, placebo-controlled, multicenter study
    (Sage Publications Inc, 2010) Cingi, Cemal; Songu, Murat; Ural, Ahmet; Yildirim, Muzeyyen; Erdogmus, Nagehan; Bal, Cengiz
    We conducted a prospective, randomized, double-blind, placebo-controlled, multicenter study to assess the efficacy of chlorhexidine gluconate/benzydamine HCl mouth spray for reducing pain and improving quality of life in patients with acute viral pharyngitis. Prior to treatment, patients rated the intensity of their pain on a visual analog scale and evaluated their quality of life on the 36-Item Short-Form Health Survey. Patients were then randomized to receive either paracetamol (acetaminophen) plus chlorhexidine/benzydamine or paracetamol plus placebo for 7 days. On days 3 and 7 of treatment, the participants again rated the intensity of their pain, and on day 7, they again rated their quality of life. A total of 164 patients were evaluable at study's end-80 in the chlorhexidine/benzydamine group and 84 in the control group. A comparison of self-evaluations revealed that the active treatment group reported less pain on both day 3 (p < 0.001) and day 7 (p = 0.002). Likewise, the chlorhexidine/benzydamine group reported a significantly better quality of life on day 7 (p < 0.001). Chlorhexidine/benzydamine was well tolerated, and no serious adverse events were observed.
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    Nasal septal body and inferior turbinate sizes differ in subjects grouped by sex and age
    (Int Rhinologic Soc, 2014) San, Turhan; Muluk, Nuray Bayar; Saylisoy, Suzan; Acar, Mustafa; Cingi, Cemal
    Objectives: To compare the size of the nasal septal body (SB) and inferior turbinate (IT) of subjects grouped by sex and age. Method: We measured SB and IT areas (in cm(2)) bilaterally in computed tomography (CT) sections of 150 paranasal sinuses from 72 males and 78 females. Results: The right and left SB areas were smaller in females than in males. In the <= 25-year-old group, the right IT (RIT) was significantly smaller in females than in males. In the 26-35 and 46-45 age groups, the right SB (RSB) was significantly smaller in females than in males. Conclusion: The nasal SB may play a role in nasal physiology similar to a turbinate and help support optimal airflow. The vascular and glandular structures of the SB should be investigated in detail, and minimal invasive procedures should be performed in nasal surgery to avoid damaging essential structures.
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    Prevalence of allergic rhinitis among the adult population in Turkey
    (Informa Healthcare, 2010) Cingi, Cemal; Topuz, Bulent; Songu, Murat; Kara, Cuneyt Orhan; Ural, Ahmet; Yaz, Aytekin; Yildirim, Muzeyyen
    Conclusion: The prevalence of self-reported and physician-diagnosed allergic rhinitis (AR) exhibits significant variability across the seven geographical regions in Turkey. Our findings may contribute to the formulation of public health policy and development of preventive and therapeutic strategies for AR in Turkey. Objective: The purpose of this study was to assess the prevalence of AR in the Turkish adult population, with emphasis on descriptive parameters in seven distinct geographical regions in Turkey. Methods: The volunteers were evaluated with a custom-designed questionnaire for AR. Sample size for the study was calculated by allowing for 2% error in prevalence along with a 95% confidence interval (CI). At the end of the study, we reached 4125 volunteers. The data were analyzed with chi
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    The Score for allergic rhinitis study in Turkey, 2020
    (Dergipark Akad, 2021) Cingi, Cemal; Muluk, Nuray Bayar; Susaman, Nihat; Küçükcan, Nagehan; Kar, Murat; Altıntaş, Mustafa; Altın, Fazilet; Eroğlu, Sinan; Kef, Kemal; İpçi, Kağan; Güven, Selis Gülseven; Dizdar, Senem Kurt; Çayır, Serkan; Salcan, İsmail; Korkmaz, Müge Özçelik; Yılmaz, Aslı Şahin; Topuz, Bülent; Başak, Sema; Ural, Ahmet; Çobanoglu, Bengü Yaldız; Erkan, Alper Nabi; Oğhan, Fatih; Eskiizmir, Görkem; Çakır, Burak Ömür; Coşkun, Berna Uslu; Kara, Cüneyt Orhan; Gültekin, Erdoğan; Üçüncü, Harun; Selçuk, Adin; Altuntaş, Emine Elif; Durmuş, Kasım; Özlügedik, Samet; Toros, Sema Zer; Karameşe, Özgür; Bayındır, Tuba; Baylan, Müzeyyen Yıldırım; İynen, İsmail; Yılmaz, Orhan; Yılmaz, Nihat; Avcı, Deniz; Aysel, Abdulhalim; Bal, Cengiz; Başer, Serdar; Bozkurt, Ziya; Çatlı, Tolgahan; Çetinkaya, Erdem Atalay; Öner, Fatih; Coşkun, Zerrin Özergin; Dizdar, Denizhan; Eksi, Erkan; Gümüşlü, Bekir Can; Kaplan, Aşkın Keskin; Kınar, Abdullah; Parıldar, Hülya; Resuli, Ali Sayed; Köroğlu, Erdem; Yazıcı, Demet; Kurt, Yücel; Dilber, Muhammet; Çukurova, İbrahim; Annesi-Maesano, Isabella
    Objective: This study aimed to determine how prevalent allergic rhinitis (AR) is in Turkey and to compare the current prevalence with the figures obtained 10 years earlier. Methods: This study included 9,017 participants. The minimum number of participants required from each center was determined via a stratified sampling technique according to regional demographic characteristics as ascertained from the last census. For each region, both men and women were administered the score for allergic rhinitis (SFAR) questionnaire and a score for each participant was calculated based on the responses supplied. Results: A total of 9,017 individuals (55.3% men and 44.7% women) took part in this study. Of these, 94.4% were urban residents and 5.6% lived in a rural setting. Of the men, 38.5% self-reported as suffering from AR. The corresponding figure in women was 40.5%. The overall prevalence of AR, as deduced on the basis of the SFAR, was found to be 36.7%. Comparing the prevalence in different regions, we found that AR was the least prevalent in the Black Sea region with a frequency of 35.8%. The highest prevalence was in the Mediterranean region, where the prevalence was 37.7%. There was no statistical significance in the apparent differences in prevalence between different geographical regions. Despite this, however, there was a clear increase in the frequency of AR over the preceding decade. This increase was most pronounced in the South-Eastern Anatolian region, where the frequency rose from 21.0% to 36.9%. Conclusion: Our results indicate that there has been a marked increase in the prevalence of AR in every region in Turkey over the last 10 years. This could be related to living conditions in urban environments. Alterations in lifestyle, urban living, air pollution causing impairments in immune defense mechanisms, and other aspects of modern lifestyles may account for the increase in AR in Turkey.
  • Küçük Resim
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    Seawater gel in allergic rhinitis: Entrapment effect and mucociliary clearance compared with saline
    (2010) Cingi, Cemal; Ünlü, Halis H.; Songu, Murat; Yalçın, Şinasi; Topçu, İsmail; Çaklı, Hamdi; Bal, Cengiz
    Objective: We performed a prospective study to investigate the the efficacy of seawater gel in reducing symptoms in patients with mild allergic rhinitis. We also aimed to investigate the impact of nasal irrigation on mucociliary clearance with seawater gel compared with saline in this patient group. Methods: The study was performed in 100 consecutive adult individuals with a history of allergic rhinitis that was not controlled by anti-allergic drugs. Patients were assigned to receive seawater gel nasal spray for 10 days. The efficacy of treatment was assessed by means of total nasal symptom score and clinical findings. Results: A statistically significant difference was found between scores of ‘nasal discharge, nasal obstruction, sneezing, nasal itching—before and after treatment (p < 0.001). Clinical findings evaluation revealed a statistically significant decrease in lower turbinate colour rating and turbinate congestion at the end of treatment (p< 0.001). Saccharin transit time decreased from baseline in the seawater trials by 12% compared with a 4% decrease for saline. The difference between the percent changes was statistically significant (t = 2.177; p < 0.05). Conclusions: The present study provides evidence that a four times daily regimen of seawater gel can be an adjunctive therapy in the patient with allergic rhinitis.
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    Use of cone beam computed tomography in otolaryngologic treatments
    (Springer, 2012) Cakli, Hamdi; Cingi, Cemal; Ay, Yazgi; Oghan, Fatih; Ozer, Torun; Kaya, Ercan
    Cone beam computed tomography (CBCT) allows us to evaluate 3-dimensional (3D) morphology of the maxillofacial skeleton and also used in dentomaxillofacial imaging to solve complex diagnostic and treatment planning problems such as craniofacial fractures, temporamandibular dysfunctions or sinus imaging. CBCT uses a rectangular or round 2D detector, which allows a single rotation of the gantry to generate a scan of the entire region of interest. Technological and application-specific factors such as development of compact, relatively low-cost, high-quality, large, flat-panel detector arrays; the availability of low-cost computers with processing power sufficient for cone beam image reconstruction; the fabrication of highly efficient radiograph tubes capable of multiple exposures necessary for cone beam scanning at prices lower than those currently used for fan beam CT; and limited volume scanning (e.g., head and neck) eliminating the need for subsecond gantry rotation speeds make this possible. The objective of this study is to review published evidence for CBCT having an important role in ORL treatments. We aimed to review all the available literature about the CBCT imagination in ORL treatments. Systematic literature search was performed using PubMed and Ovid. Additional literature was retrieved from reference lists in the articles. Systematic analysis of the literature from 1998 to 2010 was performed. A total of 40 abstracts were evaluated independently by two members of the project group, and 38 articles were included in the review.