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Öğe The association between mean platelet volume and coronary collateral circulation(Verduci Publisher, 2013) Islamoglu, Y.; Ertas, F.; Acet, H.; Elbey, M. A.; Evliyaogllu, O.; Tekbas, E.; Cil, H.BACKGROUND: Platelets are important in the pathogenesis of atherosclerotic complications. Higher mean platelet volume (MPV) levels are related to greater in vitro aggregation, and have been identified as an independent risk factor for myocardial infarction, and for death or recurrent vascular events. AIM: To determine the relationship between MPV and the coronary collateral circulation. METHODS: The sample consisted of 96 patients with coronary artery disease, and patients were separated into two groups according to their poorly developed or well-developed collateral circulation. Coronary collateral vessels were analyzed according to the Cohen and Rentrop grading system of 0-3. RESULTS: All analyses were conducted using SPSS 11.5 (SPSS for Windows 11.5, Chicago, IL, USA). Continuous variables were expressed as mean +/- SD, and categorical variables were expressed as percentages. Comparison of categorical and continuous variables between the group with well-developed coronary collateral vessels and the group with poorly developed vessels was performed using the chi-squared test and independent samples t-test, respectively. Platelet count and MPV values were similar between the two groups. CONCLUSIONS: Our study found that MPV levels are not related to coronary collateral circulation.Öğe Asymptomatic and isolated accessory mitral valve tissue in adult population: three case reports and review of the literature(Verduci Publisher, 2012) Cil, H.; Atilgan, Z. A.; Islamoglu, Y.; Yavuz, C.; Tekbas, E. O.Accessory mitral valve tissue is a rare congenital cardiac anomaly and commonly it may cause left ventricular outflow tract obstruction (LVOTO). This anomaly occurs as a part of other congenital cardiac anomalies. However, it may be seen isolated. Structures in LVOT such as tumor, vegetation, cysts may have attention for differential diagnosis. The number of cases is increasing with the routinely using of two-dimensional echocardiography. Accessory mitral valve tissue is detected first early in children with symptoms of LVOT and is very rarely diagnosed in adults. One third of cases may asymptomatic, but commonly significant left ventricular outflow tract gradient can be detected in these cases, especially adult period. Optimal treatment of this anomaly is surgery if there is a significant LVOTO. In this report, we presented the three asymptomatic adult cases with accessory mitral valve tissue, without increased gradient in LVOT. Surgical excision was recommended to the first case in another hospital with diagnosis of cardiac cyst. Two cases are presented.Öğe Complete resolution of the left ventricular pedunculated thrombus with tirofiban infusion in a patient with severe left ventricular dysfunction(Medcom Ltd, 2013) Cil, H.; Yavuz, C.; Atilgan, Z. A.; Gunduz, E.; Soydinc, S.A 28-year-old man was admitted with symptoms of heart failure. Echocardiography revealed severe left ventricular dysfunction, apical aneurysm, and a 40 x 11 mm sized mobile thrombus attached to apical septum with a narrow stalk. The patient had anterior myocardial infarction two years ago. Heparin infusion was started at 1000 IU/hour for 48 hours. There was no detected change on the size of the thrombus. Surgery recommended to the patient was refused by him because of the procedural risks. Tirofiban infusion was started. Repeat echocardiography showed significant reduction in thrombus size after 24 hours, and complete resolution of the thrombus after 48 hours. To our knowledge, this is the first case with left ventricular mobile thrombus treated successfully with tirofiban infusion. (Hong Kong j.emerg.med. 2013;20:305-308)Öğe Effect of hypoglycemic drugs on aspirin resistance in patients with diabetes mellitus(Verduci Publisher, 2012) Ariturk, Z.; Islamoglu, Y.; Gunduz, E.; Yavuz, C.; Cil, H.; Tekbas, E.; Soydinc, S.Background: Aspirin reduces the odds of an arterial thrombotic event in high-risk patients. However, 10%-20% of patients with an arterial thrombotic event who are treated with aspirin have a recurrent arterial thrombotic event during long-term followup. Aspirin resistance has been described in some patient populations such as those with an acute coronary syndrome, ischemic stroke, percutaneous coronary intervention with drug-eluting stent, stent re-stenosis, and diabetes mellitus (DM). The aim of this study was to assess aspirin resistance and to compare it to the use of oral anti-diabetic drugs and insulin in patients with diabetes. Methods and Results: Platelet aggregation was measured after aspirin treatment in 101 diabetic patients undergoing percutaneous coronary intervention. Two patient populations were included in the investigation: use of insulin (group 1) and use of oral anti-diabetic agents (OAD) (group 2) in diabetic patients. Platelet aggregation was determined using a multichannel Multiplate analyzer. Among group 1 patients, 4.7% were aspirin non-responders and among group 2 patients, 8.6% were aspirin non-responders. Statistical differences were not found between the groups (p = 0.359). Conclusions: This study demonstrated that there was no significant difference in aspirin resistance between type 2 diabetes mellitus patients on insulin treatment and type 2 diabetes mellitus patients on OAD treatment.Öğe ENTRAPPED THROMBUS IN PATENT FORAMEN OVALE COMPLICATED BY PULMONARY EMBOLISM(Elsevier Ireland Ltd, 2011) Elbey, M. A.; Acet, H.; Cil, H.; Islamoglu, Y.; Tekbas, E.; Ariturk, Z.[Abstract Not Available]Öğe GUNSHOT INJURY OF THE HEART: AN UNUSUAL LOCALIZATION OF BULLET FRAGMENT(Elsevier Ireland Ltd, 2011) Elbey, M. A.; Yavuz, C.; Islamoglu, Y.; Cil, H.; Atilgan, Z.; Tekbas, E.[Abstract Not Available]Öğe Increased echocardiographic epicardial fat thickness is related to impaired diurnal blood pressure profiles(Oxford Univ Press, 2013) Ertas, F.; Kaya, H.; Acet, H.; Cil, H.; Akyuz, A.; Islamoglu, Y.; Tekbas, E.[Abstract Not Available]Öğe Is the pepper spray a triggering factor in myocardial infarction? A case report(Verduci Publisher, 2012) Cil, H.; Atilgan, Z. A.; Islamoglu, Y.; Tekbas, E. O.; Dostbil, Z.Fourthy years old man was admitted to Emergency Department with complains of chest pain and dispnea after exposure the pepper gas that sprayed to environment during a social event. Physical examination and electrocardiogram was revealed acute myocardial infarction.Öğe Lower serum free tri-iodothyronine levels are associated with presence and severity of coronary artery disease in the euthyroid patients(Oxford Univ Press, 2012) Ertas, F.; Kaya, H.; Cil, H.; Akil, M. A.; Atilgan, Z. A.; Islamoglu, Y.; Oylumlu, M.[Abstract Not Available]Öğe The medical approaching to a pellet injury of the heart(Verduci Publisher, 2012) Elbey, M. A.; Yavuz, C.; Cil, H.; Islamoglu, Y.A 55-year-old man with multiple pellet injuries was brought to the Emergency room. In his physical examination, there were multiple wounds in face, neck, shoulders, arms, thorax and upper abdomen. The therapeutic options include pericardial drainage, conservative treatment, and surgical removal of the pellet. But, he was successfully managed with conservative medical treatment. This case showed that the treatment of heart injuries due to shotgun pellet should be individualized.Öğe QTc prolongation and torsade de pointes ventricular tachycardia in a small dose voriconazole therapy(Verduci Publisher, 2012) Elbey, M. A.; Cil, H.; Onturk, E.; Islamoglu, Y.Torsade de pointes (TdP) is a life-threatening arrhythmia that can result from long QT syndrome. Drug-induced QT prolongation is a potentially dangerous adverse effect of some drug combinations. A 34-year-old woman with history of nephrotic syndrome and rheumatic mitral valve disease was admitted to our Hospital because of high fever. The patient continued to be febrile until antifungal treatment was switched to voriconazole. The electrocardiogram demonstrated sinus tachycardia and a prolonged QTc interval of 580 ms. Patient was resuscitated with electrical cardioversion and had an emergent temporary pacemaker placed. We recommend careful monitoring for QTc prolongation and arrhythmia in patients who are receiving voriconazole, particularly those who have significant electrolyte disturbances.Öğe SAFETY AND EFFICACY OF IBUTILIDE DURING ATRIAL FIBRILLATION ABLATION(Elsevier Ireland Ltd, 2011) Aktas, M. K.; Islamoglu, Y.; Tekbas, E.; Cil, H.; Ariturk, Z.; Elbey, M. A.; Guler, A.[Abstract Not Available]Öğe STENT FRACTURE(Elsevier Ireland Ltd, 2011) Ariturk, Z.; Tekbas, E.; Islamoglu, Y.; Soydinc, S.; Davutoglu, V.; Cil, H.; Elbey, M. A.[Abstract Not Available]Öğe Successful embolectomy in a femoral artery thrombosis caused by femoral artery catheterization in a infant(Verduci Publisher, 2012) Yavuz, C.; Cil, H.; Demirtas, S.; Yolbas, I.; Benli, E.In infants, the most common cause of femoral artery is thrombosis and iatrogenic arterial injuries usually occur after femoral artery catheterization procedures. Management of this complication includes heparin infusion, thrombolytic agents, interventional radiologic procedures, surgical thrombectomy and by-pass surgery. Signs of arterial thrombosis developed after femoral artery catheterization procedure in the right lower extremity of 9-month-old female infant with methyl malonic acidemia. Heparin infusion was started after confirming the diagnosis of femoral artery thrombosis by ultrasonography. Because of there was no response to heparin treatment, thrombolytic therapy (t-PA) was started after 24 hours. Again, because of there was no response to all medication, surgical thrombectomy was performed. Was entered right common femoral artery with 3.0 F Fogarty catheter and fresh thrombus material was removed from the proximal and distal segments of the femoral artery. Antegrade and retrograde blood flow was achieved. After the procedure clinical signs and the symptoms of the thrombosis were resolved rapidly. There were no any complications in the postoperative period. This case encouraged us for using surgical thrombectomy in the treatment of femoral artery thrombosis in infants who do not respond to medication.Öğe AN UNUSUAL PRESENTATION OF HYPERTHYROIDISM: ATRIOVENTRICULAR COMPLETE HEART BLOCK(Editura Acad Romane, 2011) Ariturk, Z.; Islamoglu, Y.; Tekbas, E.; Cil, H.; Soydinc, S.; Yazici, M.Complete heart block associated with hyperthyroidism is infrequent, and the diagnosis of hyperthyroidism is usually not considered in the absence of tachycardia. A 55-year-old woman was admitted to our emergency clinic with dizziness and syncope attack. Her electrocardiogram showed complete heart block. Hyperthyroidism had been diagnosed. and she had been treated with propylthiouracil as an anti-thyroid treatment 3 years ago, although she had not taken this drug during the last 2 months. Her thyroid Junction tests showed hyperthyroidism. Antithyroid treatment was started again. Her rhythm returned from complete atrioventricular block to normal sinus rhythm on the seventh day of hospitalization.
