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    The evaluation of nephropathy risk factors in type 2 diabetes
    (Acta Medica Mediterranea, 2014) Celepkolu T.; Tanriverdi M.H.; Celik S.B.; Bucaktepe P.G.E.; Can H.; Aslan I.; Kibrisli E.
    Introduction: The prevalence of diabetes has been increasing at an alarming rate worldwide. Thus, the complications of diabetes are increasingly prevalent and each year three million people die as a result of its chronic complications. In our study, we aimed to compare nephropathic and non nephropathic patients according to socio-demographic features, biochemical parameters, and proteinuria characteristics. Methods: Data of 923 type 2 diabetic patients, who were admitted to our Department between January 2000 and December 2008, were analysed retrospectively. The records of 378 patients were included in the study and classified as normoalbuminuric, microalbuminuric and macroalbuminuric. These groups were compared in terms of demographic, clinical and laboratory findings to investigate the risk factors related to nephropathy. Results: Of the 378 patients, 224 were female (59%) and 154 were male (41%). The mean age was 58.9±9.7 years. A total of 100 patients (26.5%) with micro and macroalbuminuria were identified as nephropathic. In the nephropathic group, the levels of FBG (Fasting Blood Glucose), PBG (Postprandial Blood Glucose), HbA1c (Hemoglobin A1c=glycosylated hemoglobin), urea, and creatinine, and the duration of known diabetes were significantly increased when compared with the non-nephropathic group. Diastolic blood pressure and urea levels were significantly higher and creatinine clearance was significantly lower in the macroalbuminuric group. Conclusion: We found a significant relationship between nephropathy and HbA1c, an important indicator of blood glucose control. Therefore, it is essential to provide aggressive blood pressure management and long-term glycaemic control in order to reduce cardiovascular risk, prevent the development of diabetic nephropathy and ESRF (End Stage Renal Failure), and reduce overall mortality and morbidity. Education of diabetic patients about the risks and complications of elevated blood pressure and poor glycaemic control is a critical component of clinical practice.
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    Öğe
    Evaluation of the reaching target values in patients with hypertension and importance of tension follow-up cards
    (Acta Medica Mediterranea, 2014) Can H.; Celik S.B.; Celepkolu T.; Akbayin Z.; Guclu Y.A.; Öngel K.; Çakir L.
    Aim: To detect the efficiancy of the "tension follow-up cards", which are used to follow tension, in achieving target values in the treatment of hypertension. Material and method: The research planned as a multicenteral, noninterventional observe and follow-up. It was made in 15 different Family Health Care units in different 7 cities, in Turkey, between November 2011 and April 2012. Patients diagnosed as essential hypertension and who were already taking at least one antihypertensive medicine, who were above 18 years old, were informed about the study and accepted 529 patients were involved into the study. The patients involved were divided into two groups as "experimental group" and "control group". The patients in the experimental group were given a tension follow up card while the control group were not. Both of the groups were given appoinments for control at the end of the fourth week. For statistical analysis, chi-square test, t-test and multiple variable logistic regression analysis were used. Results: Study was performed on 529 hypertensive patients; 247 (46.7%) were in the experimental, 282 (53.3%) were in the control group. In total; 332 patients (62.8%) were women and 197 patients (37.2%) were men. Mean age for the patients was 58.15±10.68 (min:32 max:90) and mean body mass index was 30.76±5.18 (min:18.31 max:52.07). No statistical difference was found between experimental and control groups for the begining tension values, except for the first visit first systole measurement. After one month, all measurements were repeated. For all measurements in the second visit, tension values of the experimental group were statistically lower than the control group (p<0.001). Conclusion: Patients who get treatment for hypertension but don't reach target blood pressure values constitudes high risk in the society. Data obtained from the study showed that; to control hypertension effectively, patients must be under control and must participate in the follow-up actively.