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    Application of Perceived Family Support Scale to Individuals with Special Needs
    (Elsevier Science Bv, 2014) Celik, Mehmet; Ayna, Yunus Emre
    Objective: This article aims at having data on emotions which individuals with special needs feel during interactions with their families, as well as testing family social support scores for those individuals, and testing the applicability of Perceived Family Support Scale to them. Method: The Perceived Family Support Scale was applied to 127 hearing-impaired individuals who attend a vocational high-school, a secondary school or a rehabilitation center. The scale consisted of socio-demographical questions and a 20-point Perceived Family Support Scale. The participants were asked to make a selection and a sorting among those points according to the importance level of their preference by using sign language. The data were analyzed by SPSS 16 software. Findings: Out of 127 individuals participating in the study, 72 were male (56.7 of the population) and 55 were female (43.3% of the population) and their ages ranged between 10 and 20. The average score of the perceived family support was found to be 26 points for all individuals in a scale of 40. The family support perceived by the female participants was found to be higher than that of the male participants. While such factors as participants' ages, whether their parents are alive and number of siblings have inconsistent impacts on the scores of perceived family support for the participants, the study revealed that whether they live with their biological parents, having parents with high levels of education, having high income levels of the family and participants' having disabled siblings increase the participants' perceived family support scores. Result: The study aimed at gathering data on experiences and emotions which individuals with special needs have during interactions within their families, testing perceived family support they receive, testing the applicability of Perceived Family Support Scale on such individuals. It can be said that the perceived family support scores for individuals with special needs due to their hearing impairment is lower than average scores for normal individuals, which were obtained in previous studies. When we analyze the socio-demographic input and the perceived family support scores of the participating individuals with special needs due to their hearing impairment, we see that living with biological parents, parents' high levels of education, high income levels of the family and having disabled siblings increase the scores of the perceived family support. Therefore, it is thought that supporting and strengthening those individuals in terms of such characteristics may increase the level of perceived family support. (C) 2013 The Authors. Published by Elsevier Ltd.
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    Demographic, clinical and laboratory characteristics of extrapulmonary tuberculosis: Eight-year results of a multicenter retrospective study in Turkey
    (Sage Publications Ltd, 2024) Celik, Mehmet; Gurbuz, Esra; Cicek, Yeliz; Buyuktuna, Seyit Ali; Gundag, Omur; Gulderen Kuscu, Evrim; Mermutluoglu, Cigdem
    Extrapulmonary tuberculosis (EPTB) is an important public health problem due to its diverse clinical presentations, diagnostic complexities, and significant impact on patient outcomes and public health. Our study aimed to understand the sociodemographic, clinical, and laboratory characteristics as well as diagnostic and treatment modalities of adult patients with EPTB. This is a multicentric retrospective study that covers patients with EPTB cases followed up from January 2015 to December 2022 among tuberculosis (TB) dispensaries and Infectious Diseases and Clinical Microbiology clinics of 15 hospitals located in various regions of Turkey. The study included 64.6% women with a mean age of 44 years and a mortality rate of 3.5% within 1 year of diagnosis. Initial constitutional symptoms were predominantly fatigue (57%) and anorexia (53.7%). The most commonly affected sites were the lymph nodes (49.1%) and pleura (9.7%). The lumbar region was particularly involved in cases with spinal TB. Diagnostic findings included acid-fast bacilli positivity in 27.5% of cases, tuberculosis polymerase chain reaction positivity in 41%, elevated adenosine deaminase levels in 91.2% (especially in pleural and peritoneal fluids), and mycobacterial culture positivity in 40.9%. Pathology slides showed granulomatous inflammation in 97.7%. Increased C-reactive protein (CRP) levels correlated with the number of organs affected. Anti-TB treatment-related hepatotoxicity was detected in 8.9% of patients. In this study, it is important to note that the lumbar region is predominantly affected with involvement in spinal region. CRP level was consistent with the number of organ involvements and was one of the most critical results of this study.
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    The Effects of the COVID-19 Pandemic on Clinical and Laboratory Follow-up of Patients Diagnosed With Chronic Hepatitis B: A Multicenter, Prospective, Observational Study
    (Briefland, 2022) Akgul, Fethiye; Arslan, Yusuf; Celik, Mehmet; Karasahin, Omer; Celen, Mustafa Kemal
    Background: Chronic hepatitis B (CHB) patients who are under the treatment of antiviral agents should be monitored in routine control visits. However, during the COVID-19 pandemic, the visits were interrupted. Objectives: This study aimed to investigate whether these patients were affected regarding clinical, laboratory, and treatment outcomes. Methods: This prospective study consisted of CHB patients aged > 18 who were applied to 3 tertiary centers between 14 February and 30 March 2022. The patients were selected from the ones who regularly applied to outpatient clinics and under the treatment of antiviral agents before the pandemic. The demographic and laboratory values, including serologic, biochemistry, and molecular results, were compared between the 2 groups who came and did not come to control visits. Results: A total number of 220 patients were included. More than half (n = 142, 64.5%) were female. The median age was 44 years (19 - 73). A hundred and forty-two (64.5%) patients did not come to control visits during the pandemic. The most common reason was anxiety about COVID-19. The tenofovir treatment was replaced with entecavir (ETV) due to osteopenia and with alafenamide due to osteopenia and/or renal failure. The previous agents were re-started in 27 (79.5%) patients who discontinued the treatment. Conclusions: The COVID-19 pandemic negatively impacted the follow-up of CHB patients. In this regard, 15.5% of patients stopped their treatments. The patients who stopped their follow-ups and continued tenofovir disoproxil fumarate (TDF) had proteinuria and decreases in bone mineral density (BMD) and estimated glomerular filtration rate (eGFR) levels.