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    Plasma cytokine levels in ulcerative colitis
    (H G E Update Medical Publishing S A, 2007) Goral, Vedat; Celenk, Tahir; Kaplan, Abdurahman; Sit, Dede
    Background/Aims: Some immunological factors are responsible in the pathogenesis of ulcerative colitis. There is a relationship between cytokines and ulcerative colitis. Methodology: In this study 20 ulcerative colitis patients (mean age 36.2 years old, 9 women, 11 men) and 20 healthy control groups (mean age 27.2 years old, 11 women, 9 men) were involved in the study. Results: We established that IL-2Rsp, IL-6, IL-8 and IL-10 levels were different at the patients and control groups (p < 0.005). TNF-alpha and IL-1 beta were similar at the both groups. Conclusions: According to these results, IL-2Rsp, IL-6, II-8 and IL-10 play an important role in the pathogenesis of ulcerative colitis. We consider that these cytokines are beneficial parameters in the diagnosis, treatment and prognosis of ulcerative colitis.